METABOLIC SYNDROME

This study tests a new tool called the Snouda Metabolic Score (SMS) that helps doctors identify the specific metabolic problems driving Type 2 Diabetes in each patient. 150 adults will follow a personalized 24-week lifestyle and nutrition plan based on their SMS results. The goal…

This study tests whether adding exercise-focused lifestyle coaching to a personalized diet plan improves health in 435 overweight or obese adults with metabolic syndrome. Participants will either follow a diet plan alone or a diet plan plus an intelligent lifestyle program that t…

This study looks at whether extra education from a pharmacist can help people aged 18-60 who are starting a new antipsychotic medication for conditions like schizophrenia or bipolar disorder. The goal is to see if this support reduces weight gain and other metabolic side effects.…

This study tests whether a 12-week program of supervised exercise, Mediterranean diet education, and stress management workshops can improve health in 120 overweight or obese adults. Participants will wear a smart bracelet to track activity and sleep. Researchers will measure cha…

This study tests whether a non-invasive brain stimulation technique called rTMS can reduce liver fat in people with alcohol-related fatty liver disease (MetALD). 105 participants will receive either personalized rTMS, standard rTMS, or a sham (placebo) treatment over 20 sessions.…

This study tests whether taking fenugreek seed powder daily for 12 weeks can improve key signs of metabolic syndrome, such as waist size, blood pressure, cholesterol, and blood sugar. Researchers will compare fenugreek to a placebo in 28 adults aged 30 to 60 who have metabolic sy…

This study will enroll 5000 adults to see if a one-minute, single-lead ECG, analyzed by machine learning, can detect heart conditions like high blood pressure, heart failure, and diabetes. Participants will have their ECG recorded twice and compared with full medical exams. The g…

This study tests a community-based program to help Black and Hispanic teens aged 15-20 cope with chronic stress and prevent depression. Participants will join peer groups to learn skills and will be tracked for 2 years. The goal is to reduce depressive symptoms and improve physic…

This study tests whether light physical activity after meals can improve blood sugar levels in adults with metabolic syndrome and prediabetes. Twenty-five participants will try three routines in random order: sitting, a 15-minute walk, or brief resistance exercises like squats ev…

This study looks at how eating a high-fat or high-carb breakfast changes fat levels in the blood over 8 hours. Researchers will compare results among people with conditions like diabetes, fatty liver, or kidney disease, as well as healthy volunteers. Participants will have two ov…

This study follows 40 adults who recently had laparoscopic sleeve gastrectomy for obesity. Over 6 months, researchers will measure changes in blood sugar, cholesterol, gut barrier markers, and digestive symptoms. The goal is to understand how the surgery affects gut health and me…

This study looks at whether brown adipose tissue (brown fat), which burns energy as heat, can predict how well people with obesity respond to the weight loss drug semaglutide (Wegovy). Eighty adults starting semaglutide will have PET/CT scans before and after 24 weeks of treatmen…

This early-phase study looks at whether metabolic syndrome reduces brain blood flow more in women than in men. Researchers will use MRI scans and a drug called indomethacin to test this in 72 healthy adults and those with metabolic syndrome. The goal is to understand sex differen…

This 5-year study will follow 2,800 overweight or obese Chinese adults aged 18-60 to see how their health changes over time. Participants will use a smartphone app to track their data and get lifestyle support. The goal is to understand who develops diabetes or complications, and…

This observational study in Mexico will follow 30 adults already taking tirzepatide for conditions like diabetes or obesity. Researchers will use MRI scans of the knees, CT scans of the heart, and body composition tests to see how the drug affects cartilage, heart fat, and overal…

This observational study will test whether a 1-3 minute AI-powered facial scan can accurately measure vital signs like heart rate and blood pressure, as well as estimate blood sugar, cholesterol, and mental health status. Researchers will compare the scan results with standard me…

This study will compare how vegan, omnivorous, and carnivore diets affect the way LDL cholesterol particles clump together in the blood, which can lead to artery plaque. Researchers will measure blood lipids and other health markers in 90 adults aged 25-60 who have followed their…

This study will compare a carnivore diet (only animal foods) with a Mediterranean diet (fruits, veggies, grains, legumes) in 30 adults aged 30-60 with high LDL cholesterol. Over 3 weeks, researchers will measure how each diet affects cholesterol clumping, blood fats, and blood ve…

This study looks at how mental state, emotional eating, and sleep quality together influence the risk of metabolic syndrome (a cluster of conditions like high blood pressure and blood sugar) in people with schizophrenia or bipolar disorder. Researchers will measure these factors …

This study looks at how artificial sweeteners (saccharin, sucralose) and a natural one (erythritol) affect blood sugar control, blood clotting, and heart disease risk in 80 adults with prediabetes. Participants will be randomly assigned to take one sweetener or water for two week…

This study looks at a condition called 'metabolically obese normal weight' (MONW), where people have a healthy BMI but too much body fat, raising their risk for heart problems and diabetes. Researchers will study 176 young women with normal weight, measuring body fat, blood marke…

This study will follow 500 Beijing residents aged 60 and older to see how urinary function (like bladder and kidney health) relates to the development of multiple chronic conditions such as diabetes, heart disease, and Alzheimer's. Participants will have regular health checks, bl…

This study will screen up to 10,000 adults aged 18-75 who are overweight or have metabolic issues like high blood sugar or cholesterol. Researchers will use questionnaires, blood tests, and liver ultrasounds to find out how common fatty liver disease is and what factors increase …

This study will examine how metabolic syndrome—a cluster of conditions like high blood pressure, high blood sugar, and excess belly fat—relates to gastroesophageal reflux disease (GERD). Researchers will enroll 50 adults with metabolic syndrome and use an endoscopy to check for s…

This study will follow 175 children and young adults who had a bone marrow transplant before age 18. Researchers will test their thinking, memory, and attention skills, and check for links to physical health issues like metabolism and fitness. The goal is to find early warning si…