Zapping the brain to heal the liver: new trial tests TMS for fatty liver

NCT ID NCT07399600

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a non-invasive brain stimulation technique called rTMS can reduce liver fat in people with alcohol-related fatty liver disease (MetALD). 105 participants will receive either personalized rTMS, standard rTMS, or a sham (placebo) treatment over 20 sessions. The goal is to see if targeting a deep brain reward center can improve liver health.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

repetitive transcranial magnetic stimulation (rTMS)

What this could lead to

If it works, this could offer a non-invasive, drug-free way to reduce liver fat and improve metabolic health in people with alcohol-related fatty liver disease.

What could go wrong

This is an early-stage trial with only 105 participants, so results may not apply to everyone. The treatment is experimental, and its long-term benefits or risks are not yet known.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

abdominal obesity-metabolic syndrome alcoholic liver disease fatty liver disease metabolic dysfunction and alcohol associated liver disease metabolic syndrome X

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Affiliated Hospital of Hangzhou Normal University

    Hangzhou, Zhejiang, 310015, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••