Olive compound could spark brown fat to fight obesity

NCT ID NCT06484543

First seen Apr 11, 2026 · Last updated Jun 22, 2026 · Updated 13 times

Summary

This study tests whether maslinic acid, a natural compound found in olive skins, can improve metabolic health by activating brown fat—a type of fat that burns calories. Fifty adults with pre-metabolic syndrome or mild obesity will take maslinic acid or a placebo for 12 weeks. Researchers will measure changes in blood sugar, body fat, energy use, and other markers of metabolic health.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Singapore Institute of Clinical Sciences

    Singapore, Singapore

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Maslinic acid (a natural compound found in olive skins and other plants)

What this could lead to

If it works, this could point toward a simple, natural supplement to help manage obesity and related metabolic problems like insulin resistance.

What could go wrong

This is an early-stage trial with only 50 participants, all of Chinese ethnicity, so results may not apply to everyone. The compound is a nutraceutical, not a drug, so effects may be modest.

Conditions

The condition(s) this trial relates to.

abdominal obesity-metabolic syndrome diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.