Olive compound could spark brown fat to fight obesity

NCT ID NCT06484543

Ongoing Disease control Sponsor: Institute for Human Development and Potential (IHDP), Singapore Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether maslinic acid, a natural compound found in olive skins, can improve metabolic health by activating brown fat—a type of fat that burns calories. Fifty adults with pre-metabolic syndrome or mild obesity will take maslinic acid or a placebo for 12 weeks. Researchers will measure changes in blood sugar, body fat, energy use, and other markers of metabolic health.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Maslinic acid (a natural compound found in olive skins and other plants)
What this could lead to: If it works, this could point toward a simple, natural supplement to help manage obesity and related metabolic problems like insulin resistance.
What could go wrong: This is an early-stage trial with only 50 participants, all of Chinese ethnicity, so results may not apply to everyone. The compound is a nutraceutical, not a drug, so effects may be modest.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BROWN ADIPOSE TISSUE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

abdominal obesity-metabolic syndrome diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BROWN ADIPOSE TISSUE DIABETES

Contacts and locations

Locations

Singapore Institute of Clinical Sciences

Singapore, Singapore

More trials for these conditions

Other studies related to the condition(s) this trial covers.