Can a heart drug fix vessel damage in metabolic syndrome?

NCT ID NCT05711719

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether the drug vericiguat can improve the function of small blood vessels in the heart for people with metabolic syndrome (a cluster of conditions like high blood pressure and belly fat). 45 adults took either vericiguat or a placebo for 6 weeks. Researchers used MRI scans to measure changes in blood vessel size during exercise. The goal was to see if the drug could help restore normal vessel function.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for METABOLIC SYNDROME are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

abdominal obesity-metabolic syndrome coronary microvascular disorder metabolic syndrome X

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Johns Hopkins Hospital

    Baltimore, Maryland, 21287, United States