Gene test may personalize diet plans for metabolic syndrome

NCT ID NCT05495074

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a genetic score could predict how well adults with metabolic syndrome respond to a calorie-cutting diet. 115 Mexican adults followed a reduced-calorie diet for a period, and researchers measured changes in waist size, blood sugar, cholesterol, and blood pressure. The goal was to see if certain gene variants linked to amino acid metabolism could forecast who benefits most from the diet.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ATP III dietary intervention (calorie reduction with specific macronutrient distribution)
What this could lead to
If successful, this could lead to personalized diet plans based on genetics, improving weight and heart health for people with metabolic syndrome.
What could go wrong
This is a small, completed study that only looked for a link between genetics and diet response. The results may not apply to other populations or lead to a usable test.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubiran.

    Mexico City, Mexico City, 14080, Mexico

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