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Can diet and exercise boost a psoriasis drug's power? new study investigates.

NCT ID NCT03440736

Completed Disease control Sponsor: Novartis Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Apr 23, 2026 · Last updated May 15, 2026 · Updated 3 times

Summary

This study looked at 781 adults with moderate to severe plaque psoriasis and metabolic syndrome (a cluster of conditions like high blood pressure and obesity). Participants either received the drug Secukinumab alone or combined with a lifestyle intervention (diet and exercise advice). The goal was to see if the combination improved skin symptoms and heart-related health more than the drug alone. The study lasted 28 weeks, with a 28-week extension.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Novartis Investigative Site

    Langenau, Baden-Wurttemberg, 89129, Germany

  • Novartis Investigative Site

    Munich, Bavaria, 80469, Germany

  • Novartis Investigative Site

    Munich, Bavaria, 81377, Germany

  • Novartis Investigative Site

    Darmstadt, Hesse, 64283, Germany

  • Novartis Investigative Site

    Frankfurt am Main, Hesse, 60590, Germany

  • Novartis Investigative Site

    Bramsche, Lower Saxony, 49565, Germany

  • Novartis Investigative Site

    Göttingen, Lower Saxony, 37075, Germany

  • Novartis Investigative Site

    Lingen Ems, Lower Saxony, 49809, Germany

  • Novartis Investigative Site

    Cologne, North Rhine-Westphalia, 50937, Germany

  • Novartis Investigative Site

    Detmold, North Rhine-Westphalia, 32756, Germany

  • Novartis Investigative Site

    Düsseldorf, North Rhine-Westphalia, 40225, Germany

  • Novartis Investigative Site

    Dresden, Saxony, 01307, Germany

  • Novartis Investigative Site

    Leipzig, Saxony, 04103, Germany

  • Novartis Investigative Site

    Leipzig, Saxony, 04207, Germany

  • Novartis Investigative Site

    Halle, Saxony-Anhalt, 06108, Germany

  • Novartis Investigative Site

    Andernach, 56626, Germany

  • Novartis Investigative Site

    Augsburg, 86179, Germany

  • Novartis Investigative Site

    Bad Soden, 65812, Germany

  • Novartis Investigative Site

    Berlin, 10117, Germany

  • Novartis Investigative Site

    Berlin, 10783, Germany

  • Novartis Investigative Site

    Berlin, 10789, Germany

  • Novartis Investigative Site

    Berlin, 13055, Germany

  • Novartis Investigative Site

    Berlin, 13088, Germany

  • Novartis Investigative Site

    Berlin, 13125, Germany

  • Novartis Investigative Site

    Berlin, 13187, Germany

  • Novartis Investigative Site

    Berlin, 13353, Germany

  • Novartis Investigative Site

    Berlin, 13507, Germany

  • Novartis Investigative Site

    Berlin, 13597, Germany

  • Novartis Investigative Site

    Bielefeld, 33647, Germany

  • Novartis Investigative Site

    Bochum, 44791, Germany

  • Novartis Investigative Site

    Bochum, 44793, Germany

  • Novartis Investigative Site

    Bonn, 53105, Germany

  • Novartis Investigative Site

    Braunschweig, 38100, Germany

  • Novartis Investigative Site

    Darmstadt, 64283, Germany

  • Novartis Investigative Site

    Dresden, 01097, Germany

  • Novartis Investigative Site

    Düsseldorf, 40212, Germany

  • Novartis Investigative Site

    Erlangen, 91054, Germany

  • Novartis Investigative Site

    Falkensee, 14612, Germany

  • Novartis Investigative Site

    Freiburg im Breisgau, 79098, Germany

  • Novartis Investigative Site

    Friedrichshafen, 88045, Germany

  • Novartis Investigative Site

    Gera, 07548, Germany

  • Novartis Investigative Site

    Greifswald, 17475, Germany

  • Novartis Investigative Site

    Hagen, 58095, Germany

  • Novartis Investigative Site

    Hamburg, 22303, Germany

  • Novartis Investigative Site

    Hamburg, 22391, Germany

  • Novartis Investigative Site

    Hanau, 63450, Germany

  • Novartis Investigative Site

    Hanover, 30625, Germany

  • Novartis Investigative Site

    Ibbenbueren, 49477, Germany

  • Novartis Investigative Site

    Kiel, 24105, Germany

  • Novartis Investigative Site

    Löhne, 32584, Germany

  • Novartis Investigative Site

    Lüdenscheid, 58515, Germany

  • Novartis Investigative Site

    Magdeburg, 39104, Germany

  • Novartis Investigative Site

    Magdeburg, 39120, Germany

  • Novartis Investigative Site

    Mainz, 55131, Germany

  • Novartis Investigative Site

    Memmingen, 87700, Germany

  • Novartis Investigative Site

    Mönchengladbach, 41061, Germany

  • Novartis Investigative Site

    München, 80377, Germany

  • Novartis Investigative Site

    Münster, 48149, Germany

  • Novartis Investigative Site

    Oberhausen, 46147, Germany

  • Novartis Investigative Site

    Oldenburg, 26133, Germany

  • Novartis Investigative Site

    Osnabrück, 49074, Germany

  • Novartis Investigative Site

    Plauen, 08529, Germany

  • Novartis Investigative Site

    Pommelsbrunn, 91224, Germany

  • Novartis Investigative Site

    Potsdam, 14467, Germany

  • Novartis Investigative Site

    Quedlinburg, 06484, Germany

  • Novartis Investigative Site

    Remscheid, 42897, Germany

  • Novartis Investigative Site

    Seligenstadt, 63500, Germany

  • Novartis Investigative Site

    Selters, 56242, Germany

  • Novartis Investigative Site

    Simmern, 55469, Germany

  • Novartis Investigative Site

    Soest, 59494, Germany

  • Novartis Investigative Site

    Stuttgart, 70178, Germany

  • Novartis Investigative Site

    Ulm, 89081, Germany

  • Novartis Investigative Site

    Vechta, 49377, Germany

  • Novartis Investigative Site

    Wuppertal, 42109, Germany

  • Novartis Investigative Site

    Wuppertal, 42349, Germany

Conditions

Explore the condition pages connected to this study.

METABOLIC SYNDROME PSORIASIS