PCOS showdown: metformin, inositol, or diet – which wins?

NCT ID NCT07380841

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 192 women with PCOS to see which treatment works best for improving insulin resistance and other symptoms. Participants were randomly assigned to take metformin, inositol, follow a calorie-restricted diet, or combine all three for 12 weeks. The goal was to find the most effective approach for managing PCOS and its related metabolic issues.

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Conditions

The condition(s) this trial relates to.

abdominal obesity-metabolic syndrome Insulin Resistance metabolic syndrome X polycystic ovary syndrome Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Pakistan Institute of Health Sciences / Islamabad Medical and Dental College (IMDC)

    Islamabad, Islamabad, 44000, Pakistan