LOW BACK PAIN

This study looks at whether phone calls or text messages can help people with long-term low back pain use a mobile health app more regularly. About 258 participants will use an app that teaches pain education and hypnosis. Some will get extra calls or texts, while others only get…

This study tests whether better teamwork between doctors, physiotherapists, and workplace health services can help people with low back pain avoid long-term disability. About 500 adults with subacute or recurrent low back pain who are still working will receive either standard ca…

This study looks at whether a brief medical history and physical exam can accurately identify when low back pain comes from the sacroiliac joint. Researchers will compare these findings with the final diagnosis in 140 patients. The goal is to reduce the need for advanced imaging …

This study tests a wearable device called Japet.W+ that supports the lower back. Researchers want to see if wearing it during daily activities reduces pain and helps people move better. About 102 adults with chronic low back pain will either use the device plus standard care or s…

This study is testing a new way to use an already-approved spinal cord stimulator to treat chronic, hard-to-manage back and leg pain. The device sends mild electrical pulses to the spine, and the new setting (called TVP-SCS) varies the timing of those pulses. Researchers will enr…

This study tests whether low-load exercise combined with blood flow restriction cuffs can reduce pain, improve hamstring strength, and lessen disability in people with chronic low back pain. About 44 adults aged 18–45 with pain lasting over 12 weeks will participate. The goal is …

This study looks at whether watching someone else's positive or negative experience with spinal manipulation can change pain relief and inflammation in people with chronic low back pain. About 73 adults will be randomly assigned to see a positive, neutral, or negative example bef…

This study tests whether a special balance training machine can help people with long-term low back pain feel better and move easier. About 44 adults with chronic low back pain will either use the balance platform or do simple home exercises. Researchers will check pain, balance,…

This study looks at whether adding Osteopathic Manipulative Therapy (OMT) — a hands-on technique using stretching and gentle pressure — to usual VA care can improve outcomes for veterans and service members with chronic low back pain. About 48 participants will be randomly assign…

This study tests two stretching techniques—post-isometric relaxation and active isolated stretching—in 40 adults with piriformis syndrome, a condition that causes buttock and hip pain. Over two weeks, participants will receive six sessions of one stretch type plus standard physio…

This study looks at whether Baduanjin, a slow and gentle traditional Chinese exercise, can reduce chronic low back pain and improve daily function in office workers who sit for long hours. Thirty participants will either practice Baduanjin for eight weeks or receive no special tr…

This study looks at whether low-load blood flow restriction training (LL-BFR) can help young rowers with mild or recurring low back pain. Researchers want to see if this gentler method is as good as heavy lifting for building strength and preventing re-injury. About 120 rowers ag…

This study tests whether a synthetic THC drug (dronabinol) can safely reduce chronic low back pain. About 75 adults with pain lasting at least 3 months will take either the drug or a placebo daily for 8 weeks. The goal is to see if the drug is safe enough for larger trials.

This study tests whether catgut embedding—placing small threads under the skin—can reduce pain and improve daily activities in adults with chronic low back pain from lumbar spondylosis. About 66 participants will receive either catgut embedding or electro-acupuncture over 4 weeks…

This study tests whether a special type of talk-and-movement therapy (Cognitive Functional Therapy) delivered via video calls works better than online Pilates classes for older adults with chronic low back pain. About 200 people aged 60+ with pain lasting over 12 weeks will parti…

This study tests whether combining core stabilization exercises with myofascial induction therapy (a hands-on muscle release technique) can reduce low back pain, improve core endurance, and enhance quality of life in women who gave birth within the last six months. Forty particip…

This study tests three home-based programs for people with long-term muscle or joint pain (like back pain or arthritis) who also sleep poorly. Participants will be randomly assigned to 12 months of exercise, cognitive behavioural therapy for insomnia (CBT-I), or both. The goal is…

This study tests a wearable belt that senses muscle activity and gives real-time feedback through a phone app to help people with chronic low back pain perform core exercises correctly. Forty adults with non-specific low back pain will be randomly assigned to use the belt plus st…

This study tests whether using a telerehabilitation app (TRAK) for home exercises works better than a standard exercise booklet and diary for people with low back pain. Thirty adults with subacute or chronic low back pain will follow an 8-week program, and researchers will measur…

This study compares two treatments for chronic low back pain: diathermy (a deep heating therapy) and dry needling (inserting thin needles into tight muscles). Sixty adults with pain lasting over 6 weeks will receive two sessions of one treatment. Researchers will check pain, disa…

This study tests whether watching a short educational video about how TENS works can enhance its pain-relieving effect in people with acute low back pain. Forty adults will receive standard TENS and exercise therapy, with half also viewing the video. The main goal is to see if a …

This study looks at whether adding a short course of dexamethasone (a steroid) to standard ibuprofen treatment can improve pain and disability in people with acute radicular low back pain (pain that shoots from the back down the leg). About 132 adults visiting the emergency depar…

This study is testing a program called GLA:D Back, which combines education and group exercise over 10 weeks for people with persistent low back pain. The goal is to see if Canadian clinicians can adopt the program and if patients benefit. Researchers plan to enroll 2,200 partici…

This study looks at whether adding biofeedback to standard back exercises can reduce pain and improve balance, movement, and quality of life in people with chronic low back pain. About 110 adults aged 30 to 65 with ongoing pain will be split into two groups: one doing stabilizati…

This study compares a supervised mobile health app with personalized coaching to standard exercise therapy for people with chronic low back pain. About 146 adults aged 18 to 65 who have had pain for at least 12 weeks will take part. The goal is to see which approach better reduce…

This early-stage trial tests whether sodium aescinate, a compound from horse chestnut seeds, can safely reduce pain and disability in adults with chronic low back pain. Forty participants will take either the drug or a placebo twice daily for six weeks. Researchers will measure p…

This study is testing whether a device called TENS, which sends mild electrical pulses through the skin, can safely reduce chronic low back pain. Forty adults with mild pain will use the device for 20-30 minutes, five times a week for four weeks. Researchers will track pain level…

This study compares Pilates to conventional therapy for young adults aged 18-25 with non-specific low back pain. Over six weeks, 50 participants will do supervised exercises three times a week. Researchers will measure changes in posture, core strength, and flexibility to see whi…

This study tests whether a nerve block called an erector spinae plane block (ESPB) can reduce pain in adults with acute low back pain in the emergency department. 62 participants will receive either the ESPB or a sham injection. Researchers will measure pain scores for up to 2 ho…

This study follows 200 people with chronic low back pain who are scheduled for a procedure called basivertebral nerve ablation. The goal is to see how much pain and function improve over two years and to figure out which patients benefit the most. Participants will answer weekly …

This study compares two kinesio taping techniques for people with chronic low back pain. One method targets the fascia (connective tissue) in the lower back, while the other uses traditional muscle taping. Sixty adults will receive taping twice a week for two weeks. Researchers w…

This study tests whether massage therapy can reduce low back pain in healthcare workers aged 30-65. Sixty participants will receive either guideline-based or Swedish massage. The goal is to see if massage can relieve pain and improve daily function.

This study tests whether listening to music through a special app (Music Care®) can calm anxiety as well as a gas mixture (EMONO) during a CT-guided injection for low back pain. The gas can cause nausea and dizziness, and the music app has no side effects. Researchers will compar…

This study tests a full-body suit called EXOPULSE Mollii that sends mild electrical pulses to many muscles at once. It aims to reduce pain and disability in 30 adults with chronic low back pain. Participants will try both the active suit and a sham (inactive) version to see if it…

This study tests a new way to manage low back pain in primary care. It includes training for doctors, reminders, patient education, and care plans tailored to each person. About 500 patients and over 100 general practitioners in Switzerland will take part. The goal is to see if t…

This study looks at whether adding a foam pad to a standard lumbar belt makes it more comfortable and improves back support. Fifteen healthy volunteers will wear the belt with and without the pad and rate their comfort. The goal is to see if a simple change can help people with l…

This study looks at whether wearing a lumbar brace for 4 weeks after an ER visit for low back pain can lower pain, improve spine function, and reduce the need for painkillers. About 152 adults aged 18-65 in Edmonton will be enrolled. The goal is to find a safer, non-drug option f…

This study tests whether mindfulness meditation can change how the brain processes pain in people with chronic low back pain who use opioids. Researchers will measure brain activity and pain ratings in 150 adults after 8 meditation sessions. The goal is to understand the brain me…

This study looks at whether Pilates exercises can reduce low back pain in women who recently gave birth. About 48 women aged 20-30 with ongoing back pain will take part. Researchers will measure pain levels and how well the body handles pressure to see if Pilates helps.

This study compares two exercise programs—moderate-load eccentric core exercises and Pilates—in 44 adults with non-specific low back pain lasting over 3 months. Participants will do supervised sessions for 8 weeks, and researchers will measure pain, spine flexibility, core endura…

This study places a physical therapist directly in the emergency department to treat low back pain right away, instead of sending patients to an outside clinic. Researchers want to see if this approach is practical and can be done at multiple hospitals. The trial will enroll 140 …

This study tests whether adding diaphragm relaxation exercises to standard spinal stabilization exercises can reduce pain and disability in people with chronic low back pain. Researchers will measure pain, quality of life, and muscle endurance in 42 adults over eight weeks. The g…

This study tests whether a combination of exercise, posture education, and standing advice can reduce low back pain in office workers who sit at computers for long hours. Sixty participants will be split into three groups to see which approach works best. The goal is to find a pr…

This study tests a technique called ischemic preconditioning, where blood flow to one thigh is briefly and repeatedly restricted using a device. Over two weeks, 24 adults with knee osteoarthritis and low back pain will receive either the full treatment or a sham (low pressure) ve…

This study explores whether practicing QiGong—a gentle mind-body exercise—can help people with chronic low back pain by altering brain regions linked to body awareness. Sixty adults with ongoing back pain will either follow a 12-week QiGong program or do low-impact core exercises…

This study tests a multidisciplinary rehab program (Revita) for people with long-term low back pain or spine problems. The program combines physical therapy with psychological, social, or educational support over up to 36 sessions. Researchers will measure changes in disability, …

This study tests whether having a daily check-in with a physician, in addition to standard physical therapy, helps people with low back pain more than therapy alone. 74 adults aged 18-65 with subacute or chronic mechanical low back pain will be split into two groups. Both groups …

This observational study looks at how the percentage of arm loss in people with a single upper-limb amputation relates to balance, neck and back pain, daily activities, and reaction time. Participants aged 18 to 65 who use a myoelectric or bionic prosthesis will undergo non-invas…

This study uses small body-worn sensors to measure how smoothly people with chronic low back pain move their spine during bending and twisting. Researchers want to see if movement fluidity improves after a 10-day rehab program and if it relates to how much disability people repor…

This study looks at how lumbar surgery changes the way people with chronic low back pain walk. Researchers will measure walking complexity (how adaptable your stride is) before and 3 to 6 months after surgery in 32 patients. The goal is to see if pain relief from surgery outweigh…

This study looks at 179 adults with migraine who also have neck or lower back pain. Researchers want to understand if these pains share common causes, like changes in how the brain processes pain. Participants will answer questionnaires and undergo pain assessments. The goal is t…

This study is testing whether artificial intelligence can predict if someone will develop one of five common diseases: diabetes, heart disease, breast cancer, back pain, or arthritis. Researchers will collect health data from 1,000 adults aged 30 to 60, including medical records,…

This study looks at different types of low back pain in people with ankylosing spondylitis, a type of arthritis that mainly affects the spine. Researchers want to see how these pain types relate to daily function and quality of life. The study will involve 200 adults with ankylos…

This observational study aims to understand differences between people with and without low back or neck pain by comparing their health history and movement. Over 10,000 participants will wear motion sensors and complete questionnaires in a single session, with follow-ups over 5 …

This study uses ultrasound imaging and machine learning to better understand low back pain by looking at the thoracolumbar fascia, a layer of tissue in the back. Researchers will compare images from people with acute pain, chronic pain, and no pain. Some participants with chronic…

This study follows 192 women who have been pregnant before to learn why some develop pelvic or lower back pain during pregnancy and after childbirth. Researchers will measure body awareness, stress, anxiety, and inflammation to see how these factors relate to pain and balance. Th…

This study is creating and testing an Italian version of a questionnaire that measures how much chronic low back pain limits daily activities. Researchers will ask 115 adults with back pain for at least 3 months to fill out the new questionnaire along with other standard forms. T…

This study is testing whether a quick cold spray on specific ear points can change how the brain processes chronic low back pain. Sixty adults with back pain for at least 6 months will get either real or fake (sham) ear stimulation. Researchers will use brain scans (fNIRS and MRI…

This study tests a program called STEPPT, designed to help doctors refer more Hispanic patients with back or neck pain to physical therapy and help patients actually attend those appointments. The program includes training for clinic staff, culturally tailored educational materia…

This study aims to find what factors—like physical, mental, or social issues—predict whether a person with chronic low back pain will benefit from a rehab program. Researchers will follow 333 adults with pain lasting at least three months. The goal is to personalize treatments an…

This study looks at how the thoughts and beliefs of people with chronic low back pain and their physical therapists affect how well physical therapy works. Participants will receive standard care including spinal manipulation, exercise, and education. The goal is to understand th…

This study follows 211 pregnant women to find out why some develop lasting back or pelvic pain during pregnancy and after childbirth. Researchers will measure body awareness, fear of movement, stress, and inflammation through questionnaires, balance tests, and blood samples. The …

This study compares phone-based physiotherapy follow-ups to in-person visits after lumbar spine surgery. Researchers want to see if phone calls can provide the same quality of care while saving healthcare resources and reducing patient travel. 200 patients who had spine surgery a…

This study aims to find out how many medical students at the University of the West Indies, Mona, have neck or low back pain, and whether a standardized exercise program can help. About 1,000 students will take part, with some doing the exercises and others not. The researchers w…