ACUTE RESPIRATORY DISTRESS SYNDROME
Clinical trials for ACUTE RESPIRATORY DISTRESS SYNDROME explained in plain language.
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Face-Down position could save lives in critical breathing crisis
Disease control CompletedThis study tested whether placing patients with severe acute respiratory distress syndrome (ARDS) in a face-down position for at least 16 hours daily could help them survive. Researchers compared 474 critically ill patients who were either placed face-down or kept on their backs.…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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New breathing machine method tested to shield the heart during lung crisis
Disease control CompletedThis study tested two different ways to set a breathing machine for patients with severe lung failure (ARDS). The goal was to see which method better protects the patient's heart from strain. It involved 40 adults who were recently put on a breathing machine. Researchers compared…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME
Phase: NA • Sponsor: Beijing Chao Yang Hospital • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Breathing machine study aims to prevent heart damage in critically ill patients
Disease control CompletedThis study compared two different ways to set a breathing machine for patients with severe lung failure (ARDS). The goal was to see which method is better at protecting the right side of the heart from damage, a common and dangerous complication. Researchers randomly assigned 60 …
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME
Phase: NA • Sponsor: XiaoJing Zou,MD • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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Experimental stem cells tested as lifeline for COVID lung failure
Disease control CompletedThis study tested whether stem cells from donors could help patients with severe COVID-19 lung failure. Twenty hospitalized patients were randomly assigned to receive either the stem cell treatment or a placebo, along with standard hospital care. Researchers measured whether the …
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME
Phase: PHASE2 • Sponsor: Cristina Avendaño Solá • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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Simple flip could keep COVID patients off ventilators
Disease control CompletedThis study tested whether having conscious COVID-19 patients lie on their stomachs (prone position) while receiving high-flow oxygen through the nose could improve their breathing. The goal was to see if this simple, non-invasive method could help patients avoid needing to be put…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME
Phase: NA • Sponsor: University Hospital, Tours • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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Zap to the neck aims to stop brain Injury's deadly lung complication
Disease control CompletedThis small pilot study tested whether a non-invasive device that stimulates a nerve in the neck could help prevent severe lung injury in people recently hospitalized for a mild-to-moderate traumatic brain injury. The device was used alongside standard hospital care and compared t…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME
Phase: NA • Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) • Aim: Disease control
Last updated Mar 27, 2026 12:37 UTC
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Gentler breathing support tested to save more COVID-19 patients
Disease control CompletedThis study tested a gentler way to use breathing machines for hospitalized COVID-19 patients with severe lung failure. Researchers compared the standard method to an 'ultraprotective' method that uses smaller, gentler breaths. The goal was to see if this gentler approach could he…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Disease control
Last updated Mar 24, 2026 12:01 UTC
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Blood test could flag COVID patients needing ventilators
Diagnosis CompletedThis study looked back at data from 500 U.S. adults hospitalized with COVID-19. Researchers tested whether a specific blood marker (suPAR) measured early in a hospital stay could predict which patients would develop severe breathing failure needing a ventilator within 30 days. Th…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME
Sponsor: ViroGates A/S • Aim: Diagnosis
Last updated Mar 13, 2026 15:06 UTC
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New dressing could shield Life-Support patients from deadly infections
Prevention CompletedThis study tested whether using a special antiseptic dressing on the tubes of ECMO life support could prevent serious infections. It involved 270 critically ill adults with heart or lung failure who were on ECMO. Patients were randomly assigned to receive either the antiseptic dr…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Prevention
Last updated Apr 01, 2026 14:41 UTC
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Doctors test new way to gauge lung function in critically ill
Knowledge-focused CompletedThis study aimed to test a new method for measuring airway closure during normal breathing in patients with severe Acute Respiratory Distress Syndrome (ARDS) who were on ventilators in the intensive care unit. Researchers enrolled 25 critically ill patients to assess how their lu…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Apr 02, 2026 01:11 UTC
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Does lying flat change the numbers? a small study tests a critical ARDS measurement
Knowledge-focused CompletedThis study aimed to understand if a patient's position in bed changes a key measurement used to set ventilator support for people with severe lung failure (ARDS). Researchers measured pressure in the esophagus in 11 critically ill patients while they were lying flat and while the…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Apr 02, 2026 01:11 UTC
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Scientists use special imaging to see inside lungs of critically ill patients
Knowledge-focused CompletedThis study aimed to better understand how and why a treatment called prone ventilation helps patients with severe lung failure (ARDS). Researchers used a special, non-invasive imaging technique at the bedside to see how air and blood flow in the lungs changed when patients were p…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME
Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Doctors probe hidden link between breathing machines and heart failure
Knowledge-focused CompletedThis study aimed to understand how the pressure from a breathing machine (ventilator) affects heart function in patients with Acute Respiratory Distress Syndrome (ARDS). Researchers monitored 50 adults and children with ARDS to see if specific pressure levels were linked to heart…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Scientists track COVID's hidden damage in ICU patients
Knowledge-focused CompletedThis study aimed to understand how COVID-19 causes organ damage in seriously ill patients. Researchers followed 380 intensive care patients with suspected or confirmed COVID-19, collecting daily blood and urine samples. They tracked these biomarkers alongside organ function to le…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME
Sponsor: Uppsala University • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:10 UTC
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Turning patients over: a deep dive into how it helps lungs breathe
Knowledge-focused CompletedThis study aimed to better understand why placing patients with severe Acute Respiratory Distress Syndrome (ARDS) in a face-down (prone) position helps them breathe. Researchers measured pressures inside the chest and lungs of 32 critically ill patients while they were on their b…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Scientists probe lungs of critically ill flu patients
Knowledge-focused CompletedThis study aimed to better understand why some people get very sick from H1N1 flu. Researchers analyzed fluid from the lungs of 30 patients who were so ill they needed a ventilator in the intensive care unit. By studying the virus and the body's immune response in the lungs, they…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:02 UTC
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Gentle chest squeeze tested to help critical breathing
Knowledge-focused CompletedThis study tested a new idea to help patients with severe Acute Respiratory Distress Syndrome (ARDS), a dangerous lung condition. Researchers applied gentle, continuous pressure to the front of the chest to see if it could improve how oxygen moves in the lungs and help the heart …
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:16 UTC