ACUTE RESPIRATORY DISTRESS SYNDROME
Clinical trials for ACUTE RESPIRATORY DISTRESS SYNDROME explained in plain language.
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Heart drug fails to prove benefit for lung failure patients in early-stop trial
Disease control TerminatedThis study tested whether giving the heart medication metoprolol through a vein could help people with severe lung failure (ARDS) in the ICU. The goal was to see if it helped them breathe without a machine for more days. However, the trial was stopped early and only 14 people too…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME
Phase: PHASE3 • Sponsor: Consorcio Centro de Investigación Biomédica en Red (CIBER) • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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Carbon monoxide as medicine? tiny trial tests inhaled gas for lung failure
Disease control TerminatedThis early-phase trial tested whether inhaling low doses of carbon monoxide could be safe for people with severe lung injury caused by sepsis. Only 5 participants were enrolled before the study was stopped early. The goal was to see if a personalized dosing formula could safely a…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME
Phase: PHASE1 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Could a simple gas stop COVID-19 from getting worse?
Disease control TerminatedThis study tested whether breathing in nitric oxide gas could keep mild-to-moderate COVID-19 from becoming severe. Researchers enrolled 62 hospitalized adults who were breathing on their own. The goal was to see if the gas reduced the need for a breathing tube. The trial was stop…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Personalized ventilation for ARDS: early trial halted, results uncertain
Disease control TerminatedThis study tested whether setting a ventilator based on each patient's lung volume could improve outcomes for people with moderate-to-severe acute respiratory distress syndrome (ARDS). The approach used a bedside measurement to tailor the pressure applied during breathing. Howeve…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME
Phase: PHASE3 • Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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New ventilation technique tested in ICU patients with severe lung failure
Knowledge-focused TerminatedThis trial tested a new way of using a breathing machine (flow-controlled ventilation) against the standard method (pressure-controlled ventilation) in 15 ICU patients with moderate to severe acute respiratory distress syndrome (ARDS). The goal was to see if the new method uses l…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME
Phase: NA • Sponsor: Erasmus Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Brain injury and ARDS: which breathing maneuver is safer?
Knowledge-focused TerminatedThis study compared two breathing techniques (CPAP and eSigh) in 18 patients with brain injury and acute respiratory distress syndrome (ARDS). The goal was to see which method better maintains oxygen levels in the brain without causing harm. The trial was terminated early, so fin…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME
Phase: NA • Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Scientists investigate why ventilators may worsen lung infections
Knowledge-focused TerminatedThis study looked at how mechanical ventilation (breathing machines) affects the energy centers (mitochondria) of immune cells in patients with severe lung infections and acute respiratory distress syndrome (ARDS). Researchers aimed to understand why some patients get worse despi…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Scientists probe immune cells in pneumonia to unlock ARDS secrets
Knowledge-focused TerminatedThis study looked at how certain immune cells, called non-conventional T cells, behave in patients with severe pneumonia and acute respiratory distress syndrome (ARDS). Researchers collected blood and airway samples from 258 intensive care unit patients to track these cells over …
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME
Sponsor: University Hospital, Tours • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC