Brain injury and ARDS: which breathing maneuver is safer?

NCT ID NCT02574169

Terminated Knowledge-focused Sponsor: University Hospital, Toulouse Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared two breathing techniques (CPAP and eSigh) in 18 patients with brain injury and acute respiratory distress syndrome (ARDS). The goal was to see which method better maintains oxygen levels in the brain without causing harm. The trial was terminated early, so findings are limited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: alveolar recruitment maneuvers (CPAP and eSigh)
What this could lead to: If successful, this could help doctors choose safer breathing methods for patients with both brain injury and lung failure.
What could go wrong: The study was terminated early with only 18 participants, so results are very limited and may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ACUTE RESPIRATORY DISTRESS SYNDROME are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

acute respiratory distress syndrome adult acute respiratory distress syndrome brain injury hemorrhagic stroke ischemic stroke subarachnoid hemorrhage traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) CEREBRAL INJURIES

Contacts and locations

Locations

UH Caen

Caen, 140033, France
UH Clermont-Ferrand

Clermont-Ferrand, 63003, France
UH Montpellier

Montpellier, 34295, France
UH Nantes

Nantes, 44093, France
UH Toulouse

Toulouse, Midi Pyrénées, 31059, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.