Study aims to unlock secrets of lung failure in kids
NCT ID NCT04113434
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 513 children with a severe lung condition called ARDS to find different subtypes of the disease. Researchers collected blood samples to measure proteins and gene activity. The goal was to better understand the disease and help design more targeted treatments in the future.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Akron Children's Hospital
Akron, Ohio, 44308, United States
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Arkansas Children's Hospital
Little Rock, Arkansas, 72202, United States
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Children's Healthcare of Atlanta - Emory
Atlanta, Georgia, 30322, United States
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Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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Children's Hospital of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Children's Mercy Hospital
Kansas City, Missouri, 64108, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States
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Columbia University Medical Center
New York, New York, 10032, United States
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Cooperman Barnabas Medical Center
Livingston, New Jersey, 07039, United States
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Nationwide Children's Hospital
Columbus, Ohio, 43205, United States
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Penn State Hershey Children's Hospital
Hershey, Pennsylvania, 17033, United States
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Riley Children's at Indiana University Health
Indianapolis, Indiana, 46202, United States
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Texas Children's Hospital / Baylor College of Medicine
Houston, Texas, 77030, United States
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Variety Children's Hospital D/B/A Nicklaus Children's Hospital
Miami, Florida, 33155, United States
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Washington University
St Louis, Missouri, 63110, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a Lung-Opening maneuver change a key injury marker in ARDS?
- Could simply sitting up ease breathing in severe lung failure?
- Could lung fluid proteins reveal a new way to track severe lung injury?
- Could a spirometer test guide breathing support in respiratory failure?
- Which ventilator setting saves more lungs? a Head-to-Head test
- Can a single antibody turn down the immune storm in ARDS?