Could stem cells help heal lungs in severe respiratory failure?

NCT ID NCT03818854

First seen Jan 05, 2026 · Last updated May 23, 2026 · Updated 20 times

Summary

This study tested whether a single infusion of donor stem cells could help people with acute respiratory distress syndrome (ARDS), a life-threatening lung condition. About 120 adults on breathing machines received either stem cells or a placebo. The goal was to see if the treatment improved oxygen levels and lung function safely.

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Contacts and locations

Locations

  • Harborview Medical Center

    Seattle, Washington, 98112, United States

  • Memorial Hermann Hospital - Texas Medical Center

    Houston, Texas, 77030, United States

  • Oregon Health & Science University

    Portland, Oregon, 97239, United States

  • University of California Davis Medical Center

    Sacramento, California, 95817, United States

  • University of California San Francisco

    San Francisco, California, 94143, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

  • Zuckerberg San Francisco General Hospital and Trauma Center

    San Francisco, California, 94110, United States

Conditions

Explore the condition pages connected to this study.