Restrictive cardiomyopathy

This study explores whether combining a high-protein Mediterranean diet with resistance exercise can help people with heart disease build muscle and lower their risk of future heart problems. The trial enrolls adults who have completed cardiac rehab and may have low muscle mass w…

This study tests whether a three-month smartphone-supported walking program can improve daily step counts, psychological well-being, and body composition in adults with cardiovascular disease or type 2 diabetes. Participants use the Walk15 app to set personalized step goals and t…

This study tested a coaching program called MACRO-I for adults aged 70 and older who had a heart event. The program used coaches to guide patients through starting cardiac rehab, either at a center, at home, or a mix of both. 416 participants were split into the coaching group or…

This early-phase trial tested a combination of three drugs—daratumumab, ixazomib, and dexamethasone—in 21 people with AL amyloidosis, a rare disease where abnormal protein builds up in organs. The main goal was to find the safest dose and check for side effects. Researchers also …

This study tested the safety and effectiveness of eliglustat, an oral medication, in 57 children aged 2 to 17 with Gaucher disease types 1 and 3. Some children also received the standard enzyme therapy imiglucerase. Researchers measured how the drug moves through the body, side e…

This study tested a drug called ALXN2060 (acoramidis) in 25 Japanese patients with a rare heart condition called ATTR-CM, which causes heart failure. The drug is taken as a tablet twice daily. Researchers measured how far patients could walk in 6 minutes and tracked heart-related…

This early-stage trial tested a new gene therapy called FLT201 in 10 adults with Gaucher disease type 1. The therapy uses a harmless virus to deliver a working copy of the gene that produces a missing enzyme. The main goal was to check safety and see if the treatment can boost en…

This study tested the drug patisiran in 10 adults with a rare condition called ATTR amyloidosis that causes nerve damage. Participants received an IV infusion every 21 days for 24 months. Researchers measured changes in nerve function, autonomic symptoms, and quality of life to s…

This study looked at how safe and effective Vyndaqel is for people with a rare heart condition called transthyretin amyloid cardiomyopathy. Over 1,200 patients in Japan were followed while taking the drug in regular medical practice. The main goal was to track side effects and su…

This early-phase study tested a new drug called ABX1100 in 46 people, including healthy volunteers and patients with late-onset Pompe disease. The main goal was to check safety and how the drug moves through the body. Researchers gave single or multiple doses to find the right am…

This study tested the drug mepolizumab in 16 children aged 6 to 17 with hypereosinophilic syndrome (HES), a rare condition causing too many eosinophils (a type of white blood cell). The goal was to see if mepolizumab could reduce disease flares and lower the need for steroids ove…

This study looked at medical records of 50 people with a rare heart condition called ATTR-CM to see if high-dose tafamidis (Vyndamax) slows nerve damage. Researchers compared how fast nerve problems got worse before and after starting the drug. The goal was to see if the medicati…

This study tested whether a drug called mepolizumab, given after a severe COPD flare-up that required hospital care, could prevent future hospital stays or death. It involved 238 adults with eosinophilic COPD (a type with high levels of certain white blood cells). Participants re…

This phase 3 trial tested the drug patisiran in 360 people with ATTR amyloidosis with cardiomyopathy, a condition where abnormal protein builds up in the heart, making it stiff and weak. Participants received either patisiran or a placebo intravenously. The study measured how far…

This study tested a once-daily pill called orforglipron against insulin glargine in nearly 2,750 adults with type 2 diabetes, obesity or overweight, and increased cardiovascular risk. The main goal was to see if orforglipron could reduce major heart events like heart attacks or s…

This study followed 152 adults in Greece with severe eosinophilic asthma who were starting benralizumab, a medication that helps control severe asthma. Researchers measured not only standard asthma control but also quality of life, sleep, mood, and physical activity using wearabl…

This early-phase study tested a new gene therapy called ACTUS-101 in 7 adults with late-onset Pompe disease. The main goal was to check safety and side effects. Participants received a single intravenous dose, and researchers monitored their health over time.

This study tested two ways of managing breathing during heart bypass surgery to see which better prevents lung complications. Over 1,500 adults having planned heart surgery were randomly assigned to either no breathing support or gentle, low-volume breaths while on the heart-lung…

This study looked at how well benralizumab (Fasenra) works for people with severe eosinophilic asthma in real-world clinics across the Gulf, Latin America, and India. Researchers tracked 291 patients to see if their asthma control improved over time using a standard questionnaire…

This study tested whether a single dose of dantrolene, a muscle relaxant, could reduce the risk of dangerous heart rhythms in 68 people with structural heart disease who were scheduled for a procedure to treat ventricular tachycardia. Participants received either dantrolene or a …

This study looked at whether using a HEPA air purifier at home can improve lung health in adults with a type of COPD called eosinophilic COPD. 178 people took part, with half getting real purifiers and half getting fake ones. The main goal was to see if the purifiers helped with …

This study tested the long-term safety of a combination therapy (ATB200 and AT2221) in 119 adults with late-onset Pompe disease who had completed a prior study. Participants received the drugs for an extended period, and researchers tracked side effects, walking distance, and lun…

This pilot study tested a combined bone marrow and kidney transplant from a partially matched family donor in 10 people with both a blood disorder and chronic kidney disease. The goal was to treat both conditions at once and possibly reduce the need for lifelong anti-rejection dr…

This study tested an experimental drug called NNC6019-0001 in 105 people with transthyretin amyloid cardiomyopathy, a condition where abnormal proteins build up in the heart, causing heart failure. Participants received either the drug or a placebo by infusion every 4 weeks for a…

This study tested whether intensive dental cleaning and oral hygiene advice can improve gum health and also affect markers of heart disease and type 2 diabetes. About 200 adults with gum disease and either heart disease or diabetes (or prediabetes) took part. Researchers measured…

This small completed study looked at a blood filtering procedure called double-filtration plasmapheresis (DFPP) in 5 kidney dialysis patients with very high levels of lipoprotein(a), a fatty substance linked to heart disease and blood clots. The goal was to see if DFPP could lowe…

This early-stage trial tests NTLA-2001, a CRISPR-based gene editing therapy, in 72 adults with hereditary ATTR amyloidosis—a condition where abnormal protein builds up in nerves or the heart. The treatment aims to turn off the faulty gene to reduce protein levels. The study focus…

This study followed 106 adults with severe eosinophilic asthma in Poland who received mepolizumab injections every 4 weeks for at least a year. Researchers tracked asthma attacks and the need for oral steroids before and during treatment. The goal was to see if the drug helps con…

This study tested whether a drug called alirocumab, which lowers cholesterol, can reduce heart disease risk in people with HIV. The trial involved 118 adults aged 40 and older with well-controlled HIV and high heart disease risk. Participants received either alirocumab or a place…

This study looked at whether dupilumab, a drug that blocks certain immune signals, can reduce signs of autoimmunity in the airways of people with severe asthma. 30 patients were followed for 4 months. The goal was to see if this approach could help those who don't get better with…

This completed trial looked at whether taking two cholesterol-lowering drugs (rosuvastatin and ezetimibe) is more effective and safer than taking just one (rosuvastatin) for people with heart disease. 66 adults with high cholesterol were randomly assigned to one of the two treatm…

This study tested the drug dasatinib in 68 adults with several types of blood and bone marrow disorders, including certain leukemias, myelofibrosis, and mastocytosis. The goal was to see if dasatinib could help control the disease and to check its safety. Participants took dasati…

This study tested whether using cardiac MRI to guide ablation (a procedure that destroys small areas of heart tissue) can improve outcomes for people with ventricular tachycardia, a dangerous fast heart rhythm. 104 adults with structural heart disease were randomly assigned to on…

This study tested whether adding daratumumab to standard chemotherapy (CyBorD) helps people newly diagnosed with AL amyloidosis, a rare disease where abnormal proteins build up in organs. About 416 adults took part. The goal was to see if the combination leads to better blood res…

This study looked at how well the drug tafamidis 61mg works for Korean patients with a rare heart condition called transthyretin amyloid cardiomyopathy (ATTR-CM). Researchers tracked 13 patients who were already prescribed the drug in real-world clinics. They measured changes in …

This study looked at the safety of a drug called Tafamidis (brand name VyndaMx) in 6 people in India with a rare heart condition called transthyretin amyloid cardiomyopathy (ATTR-CM). In ATTR-CM, faulty proteins build up in the heart and make it harder to pump blood. Researchers …

This study looked at whether giving ulinastatin during heart surgery can lower the chance of lung complications like infections or breathing failure. Researchers analyzed data from over 4,500 patients and also used computer models to understand how the drug works. The results sug…

This study tested whether a new combination of two drugs (ATB200 and AT2221) is safe for adults with Pompe disease, a rare genetic disorder that causes muscle weakness. 29 participants received the drugs through an IV and by mouth. The main goal was to check for side effects and …

This phase 3 trial tested a new treatment for adults with late-onset Pompe disease, a rare genetic disorder that weakens muscles and breathing. Participants received either the experimental combo (cipaglucosidase alfa plus miglustat) or the current standard therapy (alglucosidase…

This study tested an experimental nasal spray called AD17002 in 40 adults with poorly controlled moderate-to-severe eosinophilic asthma. Participants self-administered the spray twice a week for six weeks. The goal was to see if it could improve lung function and reduce the need …

This phase II trial tested the drug isatuximab in 43 patients with AL amyloidosis that had come back or stopped responding to treatment. Isatuximab is a monoclonal antibody that may help stop abnormal protein buildup. The study measured how well the drug reduced disease markers a…

This phase 2 study tested a drug called belantamab mafodotin in 35 people with AL amyloidosis, a rare disease where abnormal proteins build up in organs. Participants had already tried other treatments without success. The goal was to see if the drug could reduce or eliminate tho…

This completed Phase 3 study tested whether a radioactive tracer called [18F]Florbetaben, used in PET scans, can accurately diagnose cardiac AL amyloidosis—a condition where abnormal proteins build up in the heart. 244 adults with suspected cardiac amyloidosis received a single P…

This study looked at 15 patients with a rare heart condition called wild-type transthyretin amyloid cardiomyopathy (ATTRwt) who also had signs of aortic stenosis. Researchers used dobutamine stress echocardiography—a test that uses a drug to make the heart pump harder while imagi…

This study looked at whether a special eye scan (SS-OCTA) can detect signs of cardiovascular disease. Researchers compared retinal blood vessel changes to results from a standard carotid ultrasound in 42 adults. The goal was to see if the eye scan could predict the presence or se…

This study tested whether an AI-powered smart stethoscope can accurately detect structural heart disease in over 6,600 students aged 10-18 in China. Trained staff used the device to listen to heart sounds, and the AI flagged potential issues. Students with positive results, plus …

This study tested a Turkish version of the Johns Hopkins In-Room Independence Scale, which measures a patient's ability to move, use the toilet, and think clearly while in their hospital room. Researchers worked with 100 adults who had conditions like stroke, Parkinson's, or ampu…

This pilot study tested whether a radioactive tracer called F-18 florbetapir (Amyvid) can detect amyloid protein buildup in the heart using a PET scan. Researchers enrolled 23 people with known cardiac amyloidosis and a control group without the condition. The goal was to see if …

This study tested a new contrast agent called NH002 in 36 adults with heart disease. The agent is used during heart ultrasound to make the heart's chambers and borders clearer. The main goal was to check safety by monitoring vital signs, heart activity, and allergic reactions aft…

This study screened 646 elderly Black and Hispanic patients with heart failure to find out how many have cardiac amyloidosis, a condition where abnormal proteins build up in the heart. Researchers used a special heart scan and blood tests to detect the disease. The goal was to le…

This phase 2 trial tested a radioactive tracer called 124I-AT-01 to see how well it can measure amyloid buildup in organs like the heart, kidneys, liver, and spleen using PET/CT scans. 33 adults with systemic amyloidosis received the tracer twice, six weeks apart. The goal was to…

This study looked at how often older adults with heart disease risk factors should exercise to improve fitness and blood pressure. Twenty-two participants did combined training either twice or three times a week for 12 weeks. The goal was to see which frequency worked better for …

This early-phase study tested whether losartan, a common blood pressure medication, could prevent early heart damage caused by radiation therapy in breast cancer patients. Five women with left-sided breast cancer who were scheduled for radiation took losartan. Researchers used he…

This study tested an 8-week digital lifestyle program called MYCardio-PEER for low-income adults at risk of heart disease. Participants received weekly videos and infographics on healthy eating and exercise, plus group chats with peer leaders. The goal was to see if the program i…

This study looked at whether a home-based physical activity program and computer-based cognitive training could help prevent memory loss in older women with heart disease. 253 women aged 65 and older participated. The goal was to see if these lifestyle changes could improve memor…

This completed study tested whether sending behavioral nudges through Denmark's official electronic letter system could increase flu vaccination among adults aged 18-64 with chronic diseases. Over 300,000 participants were randomly assigned to receive different types of letters o…

This study looked at two methods to reduce pain after heart surgery through a cut in the chest bone. 120 adults received either a nerve block near the breastbone, pain medicine injected into the wound, or standard painkillers. Researchers measured pain levels using a saliva test …

This completed trial tested an 8-week program called Healing Hearts Together (HHT) for couples where one partner has heart disease. 474 couples attended weekly group sessions focused on communication, emotional support, and heart health. The goal was to see if the program improve…

This study tested the drug dapagliflozin (a diabetes medicine) in 50 adults with heart failure due to amyloid cardiomyopathy, a rare condition where abnormal proteins stiffen the heart. Researchers measured changes in quality of life, walking distance, and heart stress markers ov…

This study tested whether a 20-minute session of nurse-led spiritual care, including prayer and relaxation techniques, could help heart surgery patients feel less anxious and have more stable blood pressure and heart rate before their operation. 248 adults in Indonesia took part.…

This study tested whether a 3-month yoga program could improve physical and mental health in adults over 65 who had recently finished cardiac rehab. Participants attended yoga twice a week. Researchers measured balance, muscle strength, anxiety, and mood. The goal was to see if y…

This study tested whether adding a tramadol injection to a continuous local anesthetic (levobupivacaine) delivered through a wound catheter can reduce the need for morphine after heart surgery via sternotomy. 160 adults undergoing various heart surgeries were enrolled. The goal w…

This study looked at how common muscle and posture problems are in physiotherapy students and whether a special physiotherapy program could help. 44 students with back pain and muscle tightness received treatments like trigger point release, stretching, and joint mobilization. Th…

This study tested a breathing exercise called the active cycle breathing technique in 120 adults who had just had heart surgery. The exercise combines controlled breathing, deep breaths, and huffing or coughing to help clear the lungs and improve breathing. Researchers measured w…

This study looked at whether letting patients control their own sedation during arm surgery under regional anesthesia leads to higher satisfaction compared to having an anesthesiologist control it. 70 adults having upper limb orthopedic surgery were randomly assigned to either pa…

This study tested a 9-week internet-based cognitive behavioral therapy (CBT) program designed to reduce stress, anxiety, and depression in people with stable heart disease. 215 adults with heart disease and elevated stress or mood symptoms took part. The program was personalized …

This study tested whether high-dose inspiratory muscle training (IMT) using a handheld device is safe and feasible for people with late-onset Pompe disease. 34 adults with stable Pompe disease did remote breathing exercises. Researchers measured changes in respiratory strength an…

This study tested whether adding virtual reality (VR) driving simulations to standard cardiac rehabilitation helps heart surgery patients feel less anxious and depressed. Sixty adults recovering from heart surgery took part. The results suggest VR can improve emotional well-being…

This study explored how family members share health information about genetic diseases like sickle cell, diabetes, and cancer. Over 1,000 adults completed surveys or interviews about their family health history and support. The goal was to understand social and relational factors…

This study uses advanced heart imaging to understand how blood flows inside the heart in people with cardiac amyloidosis, a condition where abnormal proteins build up in heart tissue. Researchers will compare these images with those from healthy volunteers to find unique patterns…

This study translated the Generic Functional Index, a questionnaire that measures how well people can do daily activities, into Turkish. Researchers tested it with 200 adults who have muscle or joint problems to see if it is accurate and reliable. The goal is to give Turkish-spea…

This study tested a decision algorithm to help doctors diagnose the cause of eosinophilia (high levels of a type of white blood cell). The algorithm guides which tests to do and in what order. Researchers enrolled 53 patients and measured how many followed the algorithm correctly…

This study looks at how inherited heart rhythm problems (like Long QT Syndrome) and heart muscle diseases (like Hypertrophic Cardiomyopathy) affect the quality of life and physical activity of children aged 6 to 18. Researchers will compare 107 children with these conditions to 1…

This pilot study tested whether giving inhaled nitric oxide gas during laparoscopic surgery could protect blood vessels and organs in 40 adults with heart disease. Half received the gas through their breathing tube during surgery, and half received standard care. Researchers meas…

This completed study observed 528 adults who had heart surgery and were admitted to the intensive care unit (ICU). Researchers tracked deaths, serious complications like stroke or infection, and patient details to identify risk factors. The goal is to use this information to impr…

This study tested whether a special MRI scan of the wrist can detect amyloid deposits in people with systemic amyloidosis, a condition where abnormal proteins build up in organs. Researchers enrolled 128 adults, including patients with cardiac amyloidosis and healthy volunteers. …

This study checked how often nerve damage (neuropathy) occurs in people with a rare heart condition called wild-type TTR cardiac amyloidosis. Researchers examined 65 patients using interviews, physical exams, and nerve tests (electromyograms). The goal was to find out if nerve pr…

This study looked at 150 Caribbean Hispanic adults with heart disease or stroke risk who take the blood thinner clopidogrel. Researchers wanted to see if certain gene variants affect how well the drug works. The goal is to understand why some people get less benefit and to pave t…

This study checked how well over 5,000 heart patients follow their prescribed medicine routine. Researchers asked patients about their medication habits and any side effects. The goal was to understand how many patients do not take their medicines as directed.

This study collected information from over 15,000 people hospitalized with cardiomyopathy, a heart muscle disease. Researchers looked at how much these hospital stays cost and what the money was spent on. The goal was to understand the real-world financial impact and help manage …

This completed study involved 250 adults with AL amyloidosis, a rare disease where abnormal proteins damage organs. Researchers analyzed patient samples and data to find biological markers that predict how well someone will respond to initial treatments. The goal is to help docto…

This study looked at different types of immune cells (eosinophils) in the blood of people with asthma, chronic sinusitis with nasal polyps, or both, compared to healthy volunteers. The goal was to find patterns that could help doctors choose the best targeted therapy for each pat…

This study aimed to make heart rate monitors more accurate for people with heart conditions. Researchers collected data from 138 participants, including cardiac patients and athletes, using Fitbit and Polar devices over 13 weeks. The goal was to remove false readings and develop …

This study looked at whether being physically active over a lifetime is linked to developing a rare heart disease called wild-type transthyretin amyloid cardiomyopathy. Researchers compared the exercise histories of 180 people over age 60, including those with the disease, those …

This study tested a program where doctors refer inactive people with chronic diseases (like diabetes, heart disease, or obesity) to an exercise professional for personalized counseling. The goal was to see if this referral scheme helps people become more active compared to just g…

This study looked at 22 people with severe aortic stenosis who were scheduled for valve replacement. Before surgery, they had an ultrasound of the heart, and during surgery a tiny sample of heart muscle was taken to check for scarring (fibrosis). The goal was to see if ultrasound…

This study looked at 30 people newly diagnosed with cardiac AL amyloidosis, a rare disease where abnormal proteins damage the heart. Researchers used advanced MRI, echocardiogram, and PET scans to see if these images could predict survival and show how well chemotherapy works. Th…

This study checked whether the Turkish version of the Cardiac Depression Scale (CDS) works well for people with heart disease. Researchers tested 360 Turkish adults with various heart conditions to see if the scale accurately measures depression. The goal is to give doctors a rel…

This completed study looked at 400 people with both heart disease and a mental health condition (like depression or anxiety). Researchers used questionnaires, blood tests, and imaging to find shared risk factors and biological markers. The goal was to better understand how these …

This study tested whether a special PET imaging probe called [68Ga]CBP8 can measure scarring (fibrosis) in the hearts of people with cardiac amyloidosis, a rare condition where abnormal proteins build up in the heart. Researchers compared 18 participants with cardiac amyloidosis …

This study looked at whether wearing an activity monitor (like a Fitbit) after heart surgery helps patients get moving sooner and return to their normal activity levels faster. Researchers tracked motivation, length of hospital stay, and readmission rates in 12 adults who had car…

This study looked at how the asthma drug mepolizumab affects gene activity in adults with severe eosinophilic asthma. Researchers took blood samples from 20 participants before and after 12 weeks of treatment to see which genes changed. The goal was to understand how the drug wor…

This study looked at 86 people with severe aortic valve stenosis who had valve replacement surgery. Researchers used special MRI scans to measure scarring in the heart muscle before and one year after surgery. The goal was to see if the scarring improves and whether MRI could hel…

This study followed 37 people with a genetic risk for hereditary ATTR amyloidosis over five years. Researchers measured levels of misfolded proteins in the blood to see if they could detect the earliest signs of the disease. The goal is to develop a way to catch the condition bef…

This study tested whether specially trained physiotherapists can safely diagnose and treat non-urgent muscle and joint pain in the emergency room, compared to standard care from doctors. 102 patients with back, neck, or shoulder pain were randomly assigned to either a physiothera…

This study tested whether special communication training for pharmacists and general practitioners helps them involve older patients in decisions to stop or lower medications for heart disease and diabetes. Researchers enrolled 310 patients aged 75 and older who were taking certa…

This study aimed to create and test a new questionnaire called CARD-SARC that measures how cardiac sarcoidosis affects patients' daily lives and well-being. Researchers worked with 130 adults diagnosed with cardiac sarcoidosis at two NHS specialist centres. The goal was to develo…

This study tested whether a theory-based motivational letter mailed six months in advance could increase attendance at a one-year post-cardiac rehabilitation check-up. Researchers compared 102 adults who received the letter to those who got usual care. The goal was to see if a si…

This study measured levels of brain chemicals related to oxidative stress and inflammation in people with type 1 Gaucher disease and healthy volunteers. Researchers gave 33 participants with Gaucher disease the antioxidant N-acetylcysteine (NAC) for about 90 days to see if it cha…

This study looked at how Chinese Americans talk about advance care planning—decisions about end-of-life care—with their families. Researchers interviewed religious leaders, patients with chronic diseases, and family caregivers in Chicago to understand their needs and readiness. T…

This completed study looked at 110 people with cardiac amyloidosis, a condition where protein deposits build up in the heart. Researchers implanted a small device under the skin to continuously monitor heart rhythms for up to several years. The goal was to learn more about when a…

This study looked for new biological markers to help diagnose hypereosinophilic syndrome (HES), a rare condition where too many eosinophils (a type of white blood cell) cause damage. Researchers compared blood samples from 41 people with HES, those with other causes of high eosin…

This study looked at how well a daily low-dose aspirin works in people who have both immune thrombocytopenia (low platelets) and heart disease. Only 4 adults took part. Researchers measured platelet function after aspirin to see if the standard dose is enough to prevent blood clo…

This study tested whether a systematic phone call from a medical student, supervised by a general practitioner, could reduce hospitalizations in patients with chronic heart or mental health conditions during the COVID-19 lockdown in France. Over 22,000 patients aged 70 and older …

This study looked at 320 adults who had heart surgery to see how well two different risk scores (EuroSCORE-II and POSPOM) predict the chance of dying in the hospital. Researchers calculated each patient's scores before surgery and compared them to what actually happened. The goal…

This study looked at whether orienteering (a navigation-based walk) is as good as regular walking for heart rehab. 40 people with stable heart disease took part. Researchers measured heart rate and enjoyment during both activities. The goal was to see if orienteering could be a f…

This study looked at whether a 6-minute stepper test (ST6) can accurately measure exercise tolerance in people with heart conditions undergoing rehabilitation. Researchers compared the stepper test results with the standard 6-minute walk test and a cardiac stress test in 60 patie…

This study looked at how mepolizumab, a biologic drug, changes inflammation in people with severe eosinophilic asthma. Researchers measured immune and metabolic markers in the nose, lungs, and blood of 15 adults. The goal was to better understand the drug's full impact beyond jus…

This small pilot study looked at whether simple breath and urine tests can measure how well muscles produce energy in children with metabolic myopathies (rare muscle disorders). Three participants completed a 12-week at-home physiotherapy program. The goal was to see if these non…

This completed study compared how well people with complex regional pain syndrome (CRPS), people with other muscle or bone pain, and healthy individuals can imagine movements. Researchers used a questionnaire called the MIQ-RS to measure motor imagery skills. The goal was to see …

This study looked at how many girls and young women aged 11 to 20 with chronic diseases (like diabetes or immune conditions) got the HPV vaccine, compared to those without chronic illness. Researchers reviewed records of 223 participants from a hospital in France. The goal was to…

This study tested an indoor air pollution intervention called AIRWISE in 20 adults aged 55 and older with heart disease. Participants received personal air cleaners, a color-changing air quality monitor, and educational materials. The goal was to see if they would use these tools…

This study looked at whether menopause makes the heart stiffer and reduces exercise ability in female endurance athletes. Researchers compared postmenopausal female athletes to premenopausal females and older male athletes using heart scans and exercise tests. The goal is to unde…

This completed study tested whether healthcare claims data can predict the results of a major heart trial (SURPASS-CVOT) comparing two diabetes drugs, tirzepatide and dulaglutide. Researchers analyzed records from over 44,000 people with type 2 diabetes and heart disease to see i…

This study surveyed 116 adults with chronic pain at a rehabilitation clinic to understand how their pain beliefs, spiritual well-being, and attitudes toward complementary and alternative medicine are related. Participants filled out several questionnaires about their pain, mood, …

This study tested new MRI methods to detect bleeding inside the heart muscle after a heart attack. Researchers studied 14 patients to see if these scans could better identify damage that raises the risk of heart failure. The goal was to improve imaging, not to test a treatment.

This study looked at two ways to assign care coordinators to older adults (65+) with heart disease or risk factors. One method used patients' own reports of difficulty coordinating care, while the other used usual triggers like hospital discharge. The goal was to see which approa…