Could an antioxidant help gaucher disease? new study investigates

NCT ID NCT02583672

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study measured levels of brain chemicals related to oxidative stress and inflammation in people with type 1 Gaucher disease and healthy volunteers. Researchers gave 33 participants with Gaucher disease the antioxidant N-acetylcysteine (NAC) for about 90 days to see if it changed these chemical levels. The goal was to understand the role of oxidative stress in the disease, not to test a cure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

N-acetylcysteine (NAC)

What this could lead to

If successful, this could point toward using antioxidants like NAC to reduce inflammation and oxidative stress in Gaucher disease.

What could go wrong

This is a small, early-phase study with only 33 participants, focused on measuring chemical changes rather than clinical improvement. Results may not lead to a new treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Gaucher disease Gaucher disease type I

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • New York University

    New York, New York, 10016, United States

  • University of Minnesota

    Minneapolis, Minnesota, 55455, United States