Could ditching Beta-Blockers boost heart Patients' exercise?

NCT ID NCT05019027

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether older adults with a heart condition called cardiac amyloidosis feel better and can exercise more when they stop taking beta-blockers. Twenty participants will each go through two periods: one on their beta-blocker and one off it. Researchers will measure exercise capacity and quality of life to see if stopping the drug makes a difference.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

beta blocker

What this could lead to

If successful, this could show that stopping beta-blockers helps some patients with cardiac amyloidosis feel better and exercise more.

What could go wrong

This is a very small, early-phase study with only 20 participants. Results may not apply to everyone, and stopping beta-blockers carries risks like heart rate changes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Amyloid Neuropathies, Familial amyloidosis heart disorder heart failure wild type ATTR amyloidosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Weill Cornell Medicine

    New York, New York, 10065, United States