A carpal tunnel clue to a silent heart threat?

NCT ID NCT06458374

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This study investigates whether people who had carpal tunnel surgery might have a higher chance of having ATTR amyloidosis, a condition where abnormal proteins build up in tissues, potentially affecting the heart. Researchers will biopsy tissue from about 180 patients who had carpal tunnel surgery to check for these proteins. Those with a positive biopsy will be monitored for 10 years with heart imaging to see if they develop cardiac amyloidosis, aiming to understand how often this occurs and how it progresses.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If this link is confirmed, it could lead to earlier detection of a serious heart condition through a simple carpal tunnel biopsy.
What could go wrong
This is an observational study, not a treatment trial. It may not prove cause and effect, and findings might not apply to broader populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ålesund Hospital

    RECRUITING

    Ålesund, Møre og Romsdal, 6026, Norway

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