One size Doesn't fit all: could pain 'Phenotypes' unlock better carpal tunnel care?

NCT ID NCT07754708

Not yet recruiting Disease control Sponsor: Kutahya Health Sciences University Source: ClinicalTrials.gov ↗

First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time

Summary

This study asks whether classifying people with carpal tunnel syndrome into different pain 'phenotypes' can predict how well they respond to standard rehabilitation. Researchers will enroll 50 adults diagnosed with carpal tunnel syndrome who fit the neuropathic pain profile. Participants will receive a standard program of education, splinting, and exercise, and their pain, symptoms, and hand function will be tracked to see if certain phenotypes improve more than others.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Standard rehabilitation protocol (patient education, splinting, and structured exercise)
What this could lead to: If successful, this could help doctors tailor carpal tunnel treatment based on a patient's specific pain profile, improving outcomes and reducing unnecessary procedures.
What could go wrong: This is a small, early-stage study, and the results may not apply to everyone with carpal tunnel syndrome. The benefit of phenotyping is not yet proven.

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Conditions

The condition(s) this trial relates to.

carpal tunnel syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARPAL TUNNEL SYNDROME

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