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Can gentle bone mobilization beat standard wrist stretches for carpal tunnel?

NCT ID NCT07724717

Symptom relief Sponsor: Riphah International University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This trial tests whether moving specific wrist bones (scaphoid, lunate, triquetrum) one by one relieves carpal tunnel symptoms better than moving the whole wrist. Adults aged 30–60 with at least two months of mild-to-moderate carpal tunnel syndrome are randomly assigned to one of the two manual therapy techniques. Researchers measure pain, wrist motion, and symptom severity over four weeks to see which approach offers more relief.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
manual therapy (whole wrist mobilization or specific carpal bone mobilization)
What this could lead to
If one approach works better, it could point toward a more effective physical therapy technique for carpal tunnel syndrome.
What could go wrong
This is a small, early-stage trial with only 44 participants, so results may not apply to everyone. Manual therapy carries a low risk of temporary discomfort.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

44 people

The number who actually took part.

Started

Dec 2025

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participants aged 30 to 60 years old * Both male and female participants * CTS for at least 2 months * Pain levels on the Numeric Pain Rating Scale (NPRS) between 3 and 7 * Limited range of motion and wrist pain * Patient with positive PHALEN and TINEL test Exclusion Criteria: * Prior traumatic injury of wrist * History of wrist surgery * Diagnoses of polyneuropathy, cervical radiculopathy, myelopathy, inflammatory arthritis, diabetes, thyroid disease * Presence of abnormal sensation in the wrist region * Hemorrhagic tendency and/or current anticoagulation treatment * History of whiplash injury

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Conditions

The condition(s) this trial relates to.

carpal tunnel syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Carpal tunnel syndrome

Contacts and locations

Locations

  • Riphah Rehabilitation Clinic

    Lahore, Punjab Province, Pakistan

  • Umaid Qaseem Hospital and Chest Clinic

    Lahore, Punjab Province, Pakistan

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