Heart screening study reveals hidden amyloidosis in minorities

NCT ID NCT03812172

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study screened 646 elderly Black and Hispanic patients with heart failure to find out how many have cardiac amyloidosis, a condition where abnormal proteins build up in the heart. Researchers used a special heart scan and blood tests to detect the disease. The goal was to learn how common it is in these groups and explore links to genetics and sex.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Technetium-99m-Pyrophosphate or Technetium-99m-HydroxyMethyleneDiphosphonate (radioactive tracer for imaging)
What this could lead to
If successful, this could show that screening high-risk minority groups with heart imaging helps detect cardiac amyloidosis earlier, leading to better management.
What could go wrong
This is a completed screening study, not a treatment trial. It only measures how common the condition is, so it won't directly improve health outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Amyloid Neuropathies, Familial heart failure wild type ATTR amyloidosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Boston Medical Center/Boston University Medical Center

    Boston, Massachusetts, 02118, United States

  • Columbia University Irving Medical Center

    New York, New York, 10032, United States

  • Harlem Hospital

    New York, New York, 10037, United States

  • Yale University/Yale New Haven Medical Center

    New Haven, Connecticut, 06519, United States

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