New COPD treatment cuts hospital returns in severe cases

NCT ID NCT04075331

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether a drug called mepolizumab, given after a severe COPD flare-up that required hospital care, could prevent future hospital stays or death. It involved 238 adults with eosinophilic COPD (a type with high levels of certain white blood cells). Participants received either mepolizumab or a placebo alongside standard care. The goal was to see if the drug could reduce the risk of another hospital visit or death over about a year.

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease COPD, severe early onset Eosinophilia hypereosinophilic syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • NIHR Biomedical Research Centre, Respiratory

    Leicester, Leicestershire, LE1 9QP, United Kingdom