Heart amyloid spotted by new PET tracer in pilot study
NCT ID NCT01683825
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study tested whether a radioactive tracer called F-18 florbetapir (Amyvid) can detect amyloid protein buildup in the heart using a PET scan. Researchers enrolled 23 people with known cardiac amyloidosis and a control group without the condition. The goal was to see if this non-invasive imaging method could accurately measure amyloid deposits, potentially offering a safer alternative to heart biopsies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
F-18 florbetapir (Amyvid)
What this could lead to
If successful, this imaging method could provide a non-invasive way to diagnose and monitor cardiac amyloidosis, reducing the need for biopsies.
What could go wrong
This is a small pilot study with only 23 participants, so results may not apply broadly. The imaging technique may not be sensitive or specific enough for routine use.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States