Home breathing training shows promise for pompe patients
NCT ID NCT05431127
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether high-dose inspiratory muscle training (IMT) using a handheld device is safe and feasible for people with late-onset Pompe disease. 34 adults with stable Pompe disease did remote breathing exercises. Researchers measured changes in respiratory strength and patient-reported outcomes. The goal was to see if this home-based training could improve breathing and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Inspiratory muscle training using a Pr02 mobile device
What this could lead to
If successful, this could offer a safe, home-based breathing exercise program to help people with late-onset Pompe disease strengthen their respiratory muscles and improve daily life.
What could go wrong
This was a small, early feasibility study with only 34 participants and no control group. Results may not apply to everyone, and the training might not lead to meaningful long-term improvements.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Duke University Medical Center
Durham, North Carolina, 27705, United States