MRI-Guided heart procedure aims to stop dangerous rhythms

NCT ID NCT04694079

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether using cardiac MRI to guide ablation (a procedure that destroys small areas of heart tissue) can improve outcomes for people with ventricular tachycardia, a dangerous fast heart rhythm. 104 adults with structural heart disease were randomly assigned to one of three ablation approaches: MRI-guided, MRI-aided, or standard electroanatomical mapping. The goal was to see if MRI guidance reduces the return of abnormal rhythms and makes the procedure safer and more efficient.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cardiac magnetic resonance (CMR)-guided ablation procedure

What this could lead to

If successful, this approach could make heart ablation more precise and effective, reducing the chance of dangerous heart rhythms returning.

What could go wrong

This is a completed Phase 4 study with 104 participants, but results may not apply to all patients. The benefit of MRI guidance over standard methods is still uncertain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

endomyocardial fibrosis heart disorder ventricular tachycardia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AOUPisana

    Pisa, PI, 56100, Italy

  • Azienda Ospedaliero Universitaria Senese - U.O.C. Cardiologia, Siena

    Siena, SI, Italy

  • Azienda USL Toscana Nord Ovest - U.O.C. Cardiologia, Ospedale Versilia

    Camaiore, LU, Italy

  • Azienda USL Toscana Nord Ovest- U.O.C. Cardiologia, Ospedali Riuniti - Livorno

    Livorno, LI, 57126, Italy

  • Azienda USL Toscana Sud Est

    Arezzo, AR, Italy

  • Azienda USL Toscana Sud Est- U.O.C. Cardiologia, Ospedale Misericordia - Grosseto

    Grosseto, GR, Italy

  • FTGM

    Pisa, PI, 56100, Italy