Lens disorder

This study tested a gel called Healon EndoCoat, which is used during cataract surgery to protect the eye and keep it stable. Researchers compared a new version of the gel to the current version in 165 people having cataract surgery in both eyes. The goal was to see if the new gel…

This study tested a new lens called 621 in 105 adults having cataract surgery. The lens was implanted during standard surgery to replace the cloudy natural lens. Researchers checked how well patients could see 6 months after surgery and monitored for any safety issues. The goal w…

This study looked at how well enVista Aspire intraocular lenses work in real-world cataract surgery. 335 adults received the lenses during routine cataract removal. Researchers measured vision sharpness and how satisfied patients and surgeons were with the results.

This study tested a new way to seal the small cuts made in the eye during cataract surgery. The technique, called posterior flap hydration, uses a special cannula to add fluid to the back of the wound. Researchers checked how tight the seal was right after surgery and looked at t…

This study tested two gel-like devices, Eyefill SC and Eyefill MB, used during cataract surgery to protect the eye. Researchers followed 148 adults who had cataract surgery with these devices to see if they were safe and worked as intended. The main focus was on changes in the ey…

This study tested a new type of artificial lens (PODEYE TORIC) for people having cataract surgery who also have astigmatism, a condition where the eye is shaped like a football instead of a basketball. 261 adults received either the new lens or a standard lens to see if it safely…

This study looked at the long-term safety and performance of AcrySof PanOptix trifocal lenses in 211 people who had them implanted in both eyes 3 to 5 years earlier. Researchers checked vision and recorded any eye problems or device issues. The goal was to make sure these lenses …

This study tested a toric intraocular lens implant in 40 children aged 6 to 17 with cataracts and astigmatism (a condition where the eye is shaped like a football). The goal was to see if this special lens could improve vision better than standard surgery. All children had catara…

This study tested a new modular lens called the AVL200, implanted during cataract surgery to also correct presbyopia (age-related blurry near vision). Nine people received the lens and were followed for one year. Researchers measured how well they could see at different distances…

This study tested OpHLINE, a clear gel used during cataract surgery to keep the eye stable and protect delicate cells. Researchers followed 69 adults who had cataract surgery with the gel. The gel worked well in most cases, and serious complications were rare. The results support…

This study tested a special toric lens implant (RayOne EMV Toric) in 274 adults with cataracts and mild corneal astigmatism. Participants had cataract surgery and received either the toric lens or a standard monofocal lens. The goal was to see if the toric lens safely reduces blu…

This study tested a special intraocular lens (Vivity EDOF) in 10 adults who had cataracts and mild keratoconus, a condition that thins and bulges the cornea. All participants received the lens in both eyes during standard cataract surgery. The goal was to see if the lens could pr…

This study followed 105 adults who received a special lens implant (Mini Toric Ready) during cataract surgery to also correct astigmatism. Researchers measured how well the lens improved vision and stayed in place at least one year after the procedure. The goal was to confirm the…

This study tested a new type of artificial lens, called the AT ELANA 841P, for people having cataract surgery. 284 adults with cataracts in both eyes received either the new lens or a standard lens. Researchers measured how well patients could see at different distances and check…

This early study tested a new device that aims to treat cataracts without surgery. Eleven adults with moderate cataracts were enrolled to see if the device is safe and can improve vision. The main goal was to check for eye discomfort and changes in cataract severity. Results are …

This study tested a device called REVISYON SDS 100 to see if it can safely improve vision in people with age-related cataracts without surgery. 114 adults with moderate cataracts used the device, and researchers measured changes in eyesight and cataract severity. The goal was to …

This study tested a gel called MINIVISC® PLUS, used during eye surgeries like cataract removal and glaucoma surgery to protect delicate tissues and keep the eye stable. Researchers checked if the gel was safe and worked well in 134 patients. The main focus was on eye pressure aft…

This study tested whether a steroid implant (Ozurdex) or anti-VEGF injections (Avastin, Lucentis, or Eylea) work better to prevent worsening of diabetic macular edema after cataract surgery. Sixteen adults with diabetes and pre-existing eye swelling received one treatment before …

This study tested toric intraocular lenses (IOLs) in 236 children aged 3 to 8 who had cataracts and at least 2.0 diopters of astigmatism. All children had cataract surgery and received the special lens implant. Researchers tracked their vision and eye health for three years to se…

This study tested a device that combines a bimatoprost implant with a special intraocular lens to treat both cataracts and glaucoma or high eye pressure. Twenty-four participants received the implant during cataract surgery. The main goals were to see if it lowers eye pressure an…

This study tested a single injection of dexamethasone (Dexycu) given during cataract surgery to control eye inflammation. Researchers compared 263 patients who received the injection to an external control group. The main goal was to see how many patients had no signs of inflamma…

This trial compares a telemedical device called Occyo One to the standard slit lamp exam for detecting complications after cataract surgery. About 365 patients scheduled for cataract surgery will have their eyes imaged with Occyo One before and after surgery. A remote ophthalmolo…

This study tested whether adding dexmedetomidine or dexamethasone to a local anesthetic mixture improves pain control and patient satisfaction during cataract surgery. 75 adults undergoing eye surgery received one of the two additives or a placebo. The main goal was to see how lo…

This study looked at 43 cataract surgery patients to see if a special lens (low cylinder toric IOL) improves vision more than a standard lens. The goal was to find out if the toric lens leads to better eyesight without glasses. Results focus on distance vision and how much astigm…

This study tested a newer trifocal lens implant (Clareon PanOptix Pro) against an older one (Clareon PanOptix) in 71 adults having cataract surgery in both eyes. Each person got one of each lens, so their eyes could be compared directly. The goal was to see if the newer lens prov…

This study tested whether giving mannitol (a sugar solution) through a vein before cataract surgery improves eye pressure and the depth of the front chamber of the eye. Sixty adults aged 30-80 who were having cataract surgery took part. Half received mannitol and half received a …

This study tested whether using the Systane iLux device—which applies heat and pressure to the eyelids—before cataract surgery could improve dry eye symptoms. Thirty adults scheduled for cataract surgery received the treatment in one eye. Researchers measured changes in tear film…

This study looked at whether a melt tablet containing midazolam and ketamine works as well as IV sedation for keeping people calm and pain-free during cataract surgery. Over 1,100 adults aged 55-80 took part. Researchers measured sedation levels, pain scores, and whether extra pa…

This study tested whether a single steroid injection given during cataract surgery works as well as standard steroid eye drops to control inflammation afterward. 72 adults aged 50 and older having routine cataract surgery took part. The goal was to see if the injection could simp…

This study tested a numbing injection given around both eyes to see if it safely controls pain during cataract surgery. Fifty adults received the injection, and researchers measured their pain and satisfaction. The goal was to find a better way to keep patients comfortable during…

This study tested three types of artificial lenses implanted during cataract surgery to see which gives the best vision at far, middle, and near distances. 197 people with cataracts in both eyes received one of the three lens types. The goal was to improve vision and reduce the n…

This study looked at the safety and effectiveness of a special lens (aspicio™) implanted during cataract surgery. Thirty adults who already had the lens were checked at least 3 months after surgery. The goal was to see how well they could see at different distances and if there w…

This study tested a special lens implanted during cataract surgery to see if it improves vision at far, middle, and close distances. Thirty adults with cataracts received the lens in both eyes. Researchers measured their vision and satisfaction 1 and 3 months after surgery.

This study tested whether giving older adults structured education on eye drop use and self-care after cataract surgery improves recovery. Eighty participants aged 65 to 85 were split into two groups: one received routine care, the other added periodic education sessions. Researc…

This study tested a special type of artificial lens (TECNIS Eyhance IOL) in 62 adults aged 45-75 who had cataract surgery. The goal was to see how well the lens helps people see clearly at different distances, from close up to far away. Researchers measured vision at nine distanc…

This study looked at 40 people over 45 who had cataract surgery with a special lens that helps with both near and far vision. Half of them had the surgery with digital assistance, and half without. The goal was to see if the digital help led to better vision or more satisfaction …

This study tested whether anti-inflammatory eye drops (pranoprofen or prednisolone acetate) can reduce pain during second-eye cataract surgery compared to standard lubricating drops. 126 adults aged 50 and older who had already had one cataract surgery received the drops before t…

This study tested whether a tiny eye insert called DEXTENZA, placed after cataract surgery, works better than standard eye drops alone for reducing pain and swelling. Fifty adults having cataract surgery took part. The insert slowly releases medicine over time, aiming to improve …

This study looked at whether a structured counseling session over the phone before cataract surgery could lower patients' anxiety and improve their recovery. 128 adults scheduled for cataract surgery took part. Half received the extra phone counseling, while the other half got st…

This study tested two different eye drop treatments for people with dry eye disease who were having cataract surgery. One group used a single medication (rebamipide), while the other used a combination of two medications (diquafosol and cyclosporine). The goal was to see which ap…

This study looked at two different artificial lenses used during cataract surgery to see which one gives better vision at near, middle, and far distances. 80 adults with cataracts received one of the two lenses. The goal was to find out if one lens helps people see better without…

This study tested whether a short, fast-paced video lesson (called Pecha Kucha) given before cataract surgery could improve how well patients recover. 61 adults were split into two groups: one got the video, the other got standard care. Researchers measured recovery quality using…

This study tested whether warming bupivacaine (a numbing drug) to body temperature before injecting it around the eye improves its effects for cataract surgery. 120 adults having cataract surgery received either room-temperature or warmed bupivacaine. Researchers measured how fas…

This study looked at 138 adults who had cataract surgery in both eyes. It compared two types of artificial lens implants used with a mini-monovision technique, where one eye is set for distance and the other for near vision. The goal was to see which lens gave better vision at di…

This study tested a 'gas bubble technique' to reduce damage to the cornea's inner layer after cataract surgery in 80 patients with hard cataracts. The approach aimed to help corneal cells recover and reduce swelling. Results focused on cell loss and safety, offering a potential w…

This study tested two different lens approaches for cataract surgery: one group got two different extended-depth-of-focus lenses (one in each eye), and the other got the same trifocal lens in both eyes. The goal was to see which caused fewer halos and better vision. 36 adults hav…

This study tested a new gel called PRO-149 used during cataract surgery to protect the eye. 36 adults with age-related cataracts received either the new gel or a standard gel during their operation. The main goal was to check safety by measuring changes in eye cell count and pres…

This study tested two different trifocal lens implants used during cataract surgery to see which one gives better vision. 87 people who needed cataract surgery in both eyes received one type of lens in each eye. The main goal was to measure how clearly they could see letters on a…

This study tested a special laser device (CAPSULaser) to create a precise opening in the lens capsule during cataract surgery in 24 patients with intumescent cataract, a type of dense cataract that can make surgery tricky. The goal was to see if the laser could make the opening m…

This study tested a new type of artificial lens (TECNIS Next-Generation) in 245 adults with cataracts in both eyes. The goal was to see if the new lens provides better vision at intermediate and near distances compared to a standard lens. Participants received the lens during rou…

This study tested a new type of lens (EDOF) for people having cataract surgery, comparing it to a standard lens. The goal was to see if the new lens could improve vision at different distances while being safe. 250 adults aged 45 and older with cataracts took part, and the result…

This study tested whether listening to music through headphones during cataract surgery could reduce anxiety and prevent high blood pressure. Over 300 patients took part, with some listening to music and others wearing silent headphones. The goal was to see if a simple, non-drug …

This study tested whether letting patients pick their own aromatherapy scent (lavender, geranium, lemongrass, or sandalwood) could lower anxiety before eye surgery. 64 adults undergoing short eye procedures chose their preferred scent or received an odorless placebo patch. Resear…

This study investigates whether using a lower, more natural eye pressure during cataract surgery reduces trauma to the cornea compared to traditional high-pressure methods. The Active Sentry device helps maintain stable pressure by sensing changes in the eye. Researchers will mea…

This study tested whether surgeons can safely use an Apple Vision Pro headset to view a microscope during cataract and other eye surgeries. 45 adults having elective eye surgery took part. The goal was to see if the headset is safe and comfortable for the surgeon, not to change h…

Cataracts cloud the eye's lens and can lead to blindness if untreated. This study compared two common surgical techniques—Divide-and-Conquer and Subluxation—to see which causes less damage to the cornea's inner cell layer. 294 adults having cataract surgery took part, and researc…

This study looked at 307 cataract patients who received a special lens called TECNIS PC IOL to correct both cataracts and presbyopia (age-related blurry near vision). Researchers collected information from medical records and questionnaires to see how well patients saw, how satis…

This study checked how accurate a new formula (Barrett TAL) is at picking the right lens power for cataract surgery. Over 500 people had their vision measured before and after surgery. The goal was to see if the formula helps more people get near-perfect vision without glasses af…

This study compared two devices that measure the eye before cataract surgery to help pick the right lens implant. 144 Thai adults had both measurements taken on the same day. The goal was to see which device more accurately predicted the patient's vision one month after surgery.

This study tested four different approaches to find and treat eye diseases like cataracts, glaucoma, and diabetic retinopathy in communities in Nepal. Over 87,000 people aged 50 and older took part. The goal was to see which method—comprehensive screening, cataract camps, communi…

This pilot study tested whether giving a sedative pill (alprazolam) before cataract surgery works as well as IV sedation (midazolam) in adults 65 and older. Twenty participants were randomly assigned to one of the two approaches, and researchers measured how well their thinking a…

This study looked at the costs of cataract surgery done in a doctor's office versus an ambulatory surgery center. Researchers analyzed data from 76 patients who had routine cataract surgery. The goal was to see which setting is more cost-effective.

This study looked at 30 men taking alpha-blocker drugs for urinary symptoms who were scheduled for cataract surgery. Researchers used a special eye scan to measure the thickness of iris muscles and pupil size. The goal was to see if these measurements could predict intraoperative…

This completed study looked at how well people see and how satisfied they are after getting the TECNIS Odyssey lens in both eyes during cataract surgery. Forty patients aged 50 and older were checked at least three months after surgery. Researchers measured vision at different di…

This study checked how well two different devices (OA-2000 and Pentacam AXL) agree when measuring the eye before cataract surgery. 94 cataract patients had their eyes measured once with each device. The goal was to see if the devices give the same numbers for lens power and eye s…

This completed study looked at 80 people having routine cataract surgery in both eyes. Researchers compared two different phacoemulsification devices (Quatera 700 and Centurion) to see how they affected corneal thickness and how long it took to remove the lens. The goal was to ga…

This study tested a new device called the EYESTAR 900, which uses light to take detailed measurements of the eye's shape. 29 people with healthy eyes, corneal scarring, or irregular astigmatism took part. The goal was to see how well the new scanner measures eye geometry compared…

This study looked at two different eye scanners (ARGOS and IOLMaster 700) used to measure the length of the eye in people with dense cataracts. Researchers wanted to see if the newer scanner could get accurate measurements more often, potentially reducing the need for a more invo…

This study followed 609 nearsighted adults who had lens surgery to see if a natural eye change called posterior vitreous detachment (PVD) affects their risk of retinal detachment. Participants were grouped by whether they had PVD before surgery or not, and were monitored for up t…

This study compared two different optical devices that measure the eye before cataract or presbyopia surgery. 133 patients had their eyes measured with both devices to see if the measurements matched. The goal was to help doctors choose the best tool for planning lens implants.

This study looked at how well the Clareon Vivity and Vivity Toric intraocular lenses work in people who already had cataract surgery. Researchers measured vision at different distances in 155 participants. The goal was to confirm the lenses perform as expected and support their u…

This study tested a device called IOLMASTER 700 TK to see if it can more accurately measure the eye's curvature in people who had laser vision correction and now need cataract surgery. Researchers compared four different lens calculation methods in 155 adults. The goal was to imp…

This study looked at how accurately the Alcon Vision Suite with Argos biometer predicts the right lens power for people having cataract surgery. 106 adults aged 45 and older who chose either Clareon PanOptix or AcrySof Vivity lenses took part. The goal was to see if the device he…

This study analyzed tear and eye fluid samples from 100 cataract surgery patients to find biomarkers that could predict dry eye disease after surgery. Researchers used advanced chemical analysis to look for clues in the eye's surface cells and inner fluid. The goal is to better u…

This study looked at 100 people aged 40 and older who had cataract surgery. Half had type 2 diabetes and half did not. Researchers measured changes in the thin cell layer on the inside of the cornea before and after surgery to see if diabetes affects recovery. The goal is to help…

This study checked how well a specific intraocular lens (CT LUCIA 621P) holds up at least two years after cataract surgery. Researchers looked for tiny fluid-filled bubbles called glistening and measured vision in 33 patients. The goal was to see if the lens remains safe and clea…

This study observed 5000 cataract surgery patients to see if using a special handpiece (Active Sentry) makes the procedure safer. The handpiece helps control pressure inside the eye during surgery, which may reduce the amount of energy needed and lower the risk of complications. …

This study looked at 102 cataract patients whose corneas have a higher-than-normal back curve (posterior corneal elevation ≥15 µm). Researchers compared 13 different formulas used to calculate the right lens power for surgery, to see which one gives the most accurate vision resul…

This study tested whether a large language model (like ChatGPT) could collect medical history and suggest eye tests as well as doctors do. 172 patients with non-emergency eye problems took part. The AI's performance was compared to standard care, with senior specialists checking …

This study looked at whether a central monitoring station outside the operating room could safely replace having an anesthesia nurse in each room during eye surgeries like cataract removal. Researchers compared the rate of complications (like high blood pressure or low oxygen) be…

This study looked at 400 people aged 60-90 who had cataract surgery. They received either a white or yellow artificial lens. Researchers wanted to see if the color of the lens affected sleep time, sleep quality, and mood two months after surgery. The idea is that blue light filte…

This study looked at how stable a Clareon artificial lens stays in the eye after cataract surgery. It included 34 people with either very short or very long eyes. The researchers measured changes in eye structure and vision results, but no new treatment was tested.

This study looked at why some people lose cells on the inner surface of their cornea after having a special lens implant for severe nearsightedness. Researchers compared fluid and tear samples from 126 patients having lens removal or routine cataract surgery. The goal was to see …

This study tested a new type of artificial lens (HOYA AF-1 NY-60) used during cataract surgery. The lens is designed to stay in place better and reduce clouding behind the lens. Researchers looked at how well the lens performed in 42 people with normal, short, or long eyes. The s…

This completed study tested a virtual eye model system (VEMoS) to help personalize cataract and refractive surgery. Researchers collected eye measurements from over 500 participants, including those having surgery and those with healthy eyes. The goal was to find which measuremen…

This study looked at 41 adults aged 50-90 who had cataract surgery with a special lens that corrects astigmatism. Doctors compared two methods of marking the eye before placing the lens: a digital marker and a conventional manual marker. The goal was to see which method gives bet…

This study tested whether a computer-based tutorial (CatInfo) given before the doctor visit helps cataract surgery patients understand the procedure better and shortens the time needed for the doctor to explain it. 90 adults scheduled for cataract surgery were randomly assigned t…

This completed study followed over 18,000 Taiwanese Buddhists to see if a vegetarian diet is linked to a lower risk of chronic diseases like dementia, depression, heart disease, stroke, gout, cataracts, gallstones, and urinary tract infections. Researchers compared health records…