One drop before the laser: could this simple step save your sight?

NCT ID NCT07729189

Completed Disease control Sponsor: CMH Multan Institute of Medical Sciences Source: ClinicalTrials.gov ↗

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This trial tests whether a single drop of timolol maleate, given just before Nd:YAG laser capsulotomy, can prevent a short-term rise in eye pressure. The study includes adults who developed clouding of the lens capsule months after cataract surgery. Half receive the timolol drop; the other half receive standard care. Eye pressure is measured before and one hour after the laser to see if the drop makes a difference.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: a single drop of 0.5% timolol maleate eye solution given just before laser surgery
What this could lead to: If it works, a single drop before laser treatment could become a simple, low-cost way to protect eyes from pressure spikes.
What could go wrong: This is a small, early-stage trial. The benefit may be small or not apply to all patients. Timolol can cause side effects like eye irritation or slowed heart rate.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Capsule Opacification cataract ocular hypertension prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CAPSULE OPACIFICATION OCULAR HYPERTENSION

Contacts and locations

Locations

CMH Institute of Medical Sciences

Multan, Punjab Province, 66000, Pakistan

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