Eye implant could offer long-term pressure control for glaucoma patients

NCT ID NCT03891446

Completed Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time

Summary

This study looks at the long-term safety and effectiveness of bimatoprost SR, a tiny implant placed in the eye that slowly releases medication to lower eye pressure. It includes people with open-angle glaucoma or ocular hypertension who have already used bimatoprost SR in earlier studies. Researchers will track how long the implant works before retreatment is needed and monitor for any side effects over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: bimatoprost SR, an eye implant that slowly releases medication to lower eye pressure
What this could lead to: If successful, this could confirm that bimatoprost SR is a safe, long-lasting option for controlling eye pressure, reducing the need for daily eye drops.
What could go wrong: This is an extension study, so it builds on earlier results. Possible side effects include eye irritation or inflammation, and the implant may not work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

ocular hypertension open-angle glaucoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OCULAR HYPERTENSION OPEN ANGLE GLAUCOMA

Contacts and locations

Show contact details

Locations

AOU Policlinico G. Rodolico - San Marco /ID# 240305

Catania, 95123, Italy
ASL 2 Abruzzo Lanciano-Vasto-Chieti /ID# 240217

Chieti, 67100, Italy
Addenbrookes Hospital /ID# 240351

Cambridge, Cambridgeshire, CB2 2QQ, United Kingdom
Advancing Vision Research /ID# 240288

Smyrna, Tennessee, 37167, United States
Albemarle Clinical Trials LLC /ID# 240219

Elizabeth City, North Carolina, 27909, United States
Angeles Eye Institute /ID# 250397

Culver City, California, 90232, United States
Arizona Eye Center - West Ray Road /ID# 240239

Chandler, Arizona, 85224, United States
Arizona Glaucoma Specialists /ID# 240212

Phoenix, Arizona, 85050-4265, United States
Asan Medical Center /ID# 240286

Seoul, Seoul Teugbyeolsi, 05505, South Korea
Asheville Eye Associates /ID# 240202

Asheville, North Carolina, 28803, United States
Asian Eye Institute /ID# 240213

Makati City, 1200, Philippines
Asian Eye Institute /ID# 240214

Makati City, 1200, Philippines
Azienda Ospedaliera di Perugia - Ospedale S. Maria della Misericordia /ID# 240310

Perugia, 06156, Italy
Azienda Ospedaliero Universitaria Pisana /ID# 240301

Pisa, 56126, Italy
Bergstrom Eye Research LLC /ID# 240257

Fargo, North Dakota, 58103, United States
Bnai Zion Medical Center /ID# 240297

Haifa, 3339419, Israel
Bostan Diagnostic Eye Center /ID# 240268

Cairo, Egypt
Bruce Segal, MD /ID# 240292

Delray Beach, Florida, 33484-6540, United States
CHU Bordeaux - Hopital Pellegrin /ID# 240316

Bordeaux, New Aquitaine, 33076, France
Capital Eye Specialists /ID# 240259

Wellington, 6011, New Zealand
Centre Ophtalmologique Pôle Vision /ID# 240256

Écully, Rhone, 69130, France
Centro Oftalmologico Macula Diagnostico and Tratamiento /ID# 240269

Lima, LIMA 27, Peru
Centrum Diagnostyki i Mikrochirurgii Oka - LENS sp. z o.o /ID# 240248

Olsztyn, Warmian-Masurian Voivodeship, 10-424, Poland
Charlotte Eye Ear Nose And Throat Associates- Southpark /ID# 240339

Charlotte, North Carolina, 28210, United States
Chicago Eye Specialists /ID# 240270

Bedford Park, Illinois, 60638, United States
Clinica De Oftalmologia Nova Campinas /ID# 240271

Campinas, São Paulo, 13092-108, Brazil
Clinica Privada de Ojos /ID# 240272

Mar del Plata, Buenos Aires, 7600, Argentina
Clinica de Oftalmologia Sandiego /ID# 240233

Medellín, Antioquia, 050016, Colombia
Clinical Eye Research of Boston LLC /ID# 240203

Winchester, Massachusetts, 01890, United States
Clinical ophthalmology hospital n.a. V.P. Vihodtsev. /ID# 240253

Omsk, Omsk Oblast, 644024, Russia
Coastal Research Associates /ID# 240192

Roswell, Georgia, 30076, United States
Colorado Eye Institute /ID# 248910

Colorado Springs, Colorado, 80924-7003, United States
Consultorio Oftalmologico Dr. Fabian Lerner /ID# 240247

CABA, Buenos Aires, 1122, Argentina
DCT Shah Eye Research Institut /ID# 240306

Mission, Texas, 78572, United States
Duplicate_Ain Shams University Hospital /ID# 240338

Cairo, Egypt
Duplicate_Emory University /ID# 240328

Atlanta, Georgia, 30322-1013, United States
Duplicate_Lakeside Vision Center /ID# 240204

Irvine, California, 92604, United States
Duplicate_Martel Eye Medical Group /ID# 240291

Rancho Cordova, California, 95670-2968, United States
Duplicate_NHS Lothian /ID# 240318

Edinburgh, EH3 9HE, United Kingdom
Duplicate_Optimum Profesorskie Centrum Okulistyki Sp. z o.o. /ID# 240307

Gdansk, Pomeranian Voivodeship, 80-809, Poland
Duplicate_Seoul National University Hospital /ID# 240262

Seoul, 03080, South Korea
Duplicate_Tulane University /ID# 240327

New Orleans, Louisiana, 70112-2699, United States
Emerson Clinical Research Institute - Falls Church /ID# 240274

Falls Church, Virginia, 22046, United States
Eskisehir Osmangazi University Medical School /ID# 240225

Eskişehir, 26480, Turkey (Türkiye)
Eye Associates of Fort Meyers /ID# 240218

Fort Myers, Florida, 33901, United States
Eye Associates of New Mexico /ID# 240216

Albuquerque, New Mexico, 87109, United States
Eye Associates of North Jersey /ID# 250445

Dover, New Jersey, 07801-1629, United States
Eye Specialty Group /ID# 240241

Memphis, Tennessee, 38120, United States
Eye associates /ID# 240265

San Antonio, Texas, 78229, United States
Fraser Eye Center /ID# 240245

Fraser, Michigan, 48026, United States
Fundacion Oftalmologica Nacional /ID# 240226

Bogotá, Bogota D.C., 110231, Colombia
Fundacion Oftalmologica de Santander - FOSCAL /ID# 240634

Bucaramanga, Santander Department, 681004, Colombia
Galilee Medical Center /ID# 251967

Nahariya, Northern District, 2210001, Israel
Glaucoma Care Center /ID# 250978

Livingston, New Jersey, 07039, United States
Glaucoma associates/consultants of the capital region /ID# 240195

Slingerlands, New York, 12159, United States
Hamilton Glaucoma Center Shiley Eye Center UCSD /ID# 240196

La Jolla, California, 92093, United States
Horizon Eye Specialists & Lasik Centers /ID# 240255

Sun City, Arizona, 85351, United States
Hospital Clinico San Carlos /ID# 240303

Madrid, 28040, Spain
Hospital Oftalmologico Medicina dos Olhos /ID# 240277

Osasco, São Paulo, 0601-8180, Brazil
Hospital Sao Paulo /ID# 240278

São Paulo, 04023-062, Brazil
Hospital Universitario Austral /ID# 240331

Pilar, Buenos Aires, 1629, Argentina
Hospital Universitario Reina Sofia /ID# 240322

Córdoba, 14004, Spain
Hospital Universitario Virgen Macarena /ID# 240325

Seville, 41009, Spain
Hospital de Olhos de Mato Grosso Do Sul /ID# 240276

Campo Grande, Mato Grosso do Sul, 79002-075, Brazil
Houston Eye Associates /ID# 240340

Houston, Texas, 77025, United States
IN Univ School of Medicine /ID# 240294

Indianapolis, Indiana, 46202-2884, United States
International Research Center /ID# 240346

Tampa, Florida, 33603, United States
Internationale Innovative Ophthalmochirurgie /ID# 240232

Düsseldorf, North Rhine-Westphalia, 40212, Germany
Keystone Research LTD /ID# 240185

Austin, Texas, 78731-4203, United States
Klinika Diagnostyki i Mikrochirurgii Jaskry /ID# 240258

Lublin, Lublin Voivodeship, 20-079, Poland
Kovach Eye Institute /ID# 250442

Elmhurst, Illinois, 60126-2821, United States
Legacy Devers Eye Institute /ID# 240210

Portland, Oregon, 97210, United States
Levenson Eye Associates- Riverside Park Place /ID# 240209

Jacksonville, Florida, 32204, United States
Logan Ophthalmic Research Inc. /ID# 240280

Tamarac, Florida, 33321, United States
M&M Eye Institute /ID# 240236

Prescott, Arizona, 86301, United States
Maharaj Nakorn Chiang Mai Hospital /ID# 240194

Chiang Mai, 50200, Thailand
Marmara Universitesi Pendik Egitim ve Arastirma Hastanesi /ID# 240296

Istanbul, 34899, Turkey (Türkiye)
MedEye Associates /ID# 240333

Miami, Florida, 33143, United States
Medical Center Ophthalmology Associates /ID# 240208

San Antonio, Texas, 78240-1502, United States
Midwest Vision Research Foundation at Pepose Vision Institute /ID# 250402

Chesterfield, Missouri, 63017, United States
Montefiore Hospital /ID# 240324

The Bronx, New York, 10467-2404, United States
Nature Coast Clinical Research - Crystal River /ID# 240334

Crystal River, Florida, 34429, United States
North Bay Eye Associates Inc. /ID# 248912

Petaluma, California, 94954-2387, United States
Ocni klinika Pardubice /ID# 240347

Pardubice, 530 02, Czechia
Oftalmika sp. z o.o. /ID# 240201

Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-631, Poland
Oftalmología Global /ID# 240244

Rosario, Santa Fe Province, 2000, Argentina
Oftar Mendoza /ID# 240308

Mendoza, 1019, Argentina
Oklahoma Eye Surgeons /ID# 250430

Oklahoma City, Oklahoma, 73112, United States
Ophthalmic Consultant Centres /ID# 240205

Mississauga, Ontario, L4W 1W9, Canada
Ophthalmic Consultants Long Island /ID# 240211

Oceanside, New York, 11572, United States
Pacific Eye Associates /ID# 240234

San Francisco, California, 94115, United States
Peregrine Eye and Laser Institute /ID# 240260

Makati City, 1209, Philippines
Piedmont Eye Center /ID# 240187

Lynchburg, Virginia, 24502, United States
Plano Office /ID# 240243

Plano, Texas, 75093, United States
Pretoria Eye Institute - Private Practice /ID# 240223

Pretoria, Gauteng, 0083, South Africa
Private Practice - Dr. James D. Branch /ID# 240188

Winston-Salem, North Carolina, 27101, United States
Queen Elizabeth II Health Sciences Centre - Victoria General /ID# 240336

Halifax, Nova Scotia, B3H 2Y9, Canada
Rambam Health Care Campus /ID# 240332

Haifa, 3109601, Israel
Rigshospitalet Glostrup /ID# 240330

Glostrup Municipality, Capital Region, 2600, Denmark
Rochester Ophthalmological Group PC /ID# 240290

Rochester, New York, 14618-2616, United States
Rutgers New Jersey Medical School Campus, Doctors Office Center /ID# 240181

Newark, New Jersey, 07103-2425, United States
S. Fyodorov Eye Microsurgery Federal State Institution /ID# 240251

Novosibirsk, Novosibirsk Oblast, 630071, Russia
Sacramento Eye Consultants /ID# 240263

Sacramento, California, 95815, United States
Samsung Medical Center /ID# 240335

Seoul, Seoul Teugbyeolsi, 06351, South Korea
San Antonio Eye Center /ID# 240238

San Antonio, Texas, 78215, United States
Scott and Christie and Associates /ID# 240189

Cranberry Township, Pennsylvania, 16066, United States
Singapore National Eye Centre /ID# 240224

Singapore, 168251, Singapore
Specialty Retina Center /ID# 240254

Coral Springs, Florida, 33067, United States
Tekwani Vision Center /ID# 240220

St Louis, Missouri, 63128, United States
Tel Aviv Sourasky Medical Center /ID# 240311

Tel Aviv, Tel Aviv, 6423906, Israel
Thammasat University Hospital /ID# 240231

Pathum Thani, 12120, Thailand
The Chinese University of Hong Kong /ID# 240283

Hong Kong, Hong Kong
The Clinical Trials Network (CTNx) /ID# 240284

Redding, California, 96001, United States
The Eye Care Institute /ID# 240289

Louisville, Kentucky, 40206-1738, United States
The Eye Research Foundation /ID# 240186

Newport Beach, California, 92663-3637, United States
The Lady Davis Carmel Medical Center /ID# 240293

Haifa, 34362, Israel
Trinity Research Group /ID# 240190

Dothan, Alabama, 36301, United States
Universitaetsklinikum Magdeburg /ID# 240314

Magdeburg, 39120, Germany
Universitair Ziekenhuis Leuven /ID# 240312

Leuven, Vlaams-Brabant, 3000, Belgium
University of Illinois Hospital and Health Sciences System /ID# 250981

Chicago, Illinois, 60607, United States
University of South Florida- Neuroscience Institute /ID# 250980

Tampa, Florida, 33613, United States
Vanderbilt Eye Institute /ID# 252659

Nashville, Tennessee, 37232-0025, United States
Vistar Eye Center /ID# 240198

Roanoke, Virginia, 24011, United States
Wolstan & Goldberg Eye Associates /ID# 240221

Torrance, California, 90505, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.