Senile cataract

This early study is testing a robot-assisted system for cataract surgery in 30 adults aged 40 to 75. The robot is designed to help surgeons be more precise and improve safety compared to standard surgery. The main goal is to check for any eye-related side effects. If it works wel…

This study is testing a new device called the Veritas Vision System for cataract surgery. The goal is to see if it uses less energy and causes less damage to the cells on the inside of the eye. Researchers will follow 50 adults for 3 months after surgery to check eye health and v…

This study tests a new type of lens implant (extended depth of focus IOL) for people with age-related cataracts. The lens is designed to provide clear vision at multiple distances, potentially reducing the need for glasses after surgery. About 220 adults will be randomly assigned…

This study compares standard monofocal intraocular lenses (IOLs) with enhanced monofocal IOLs in 461 people having cataract surgery. The goal is to see if the enhanced lenses improve vision at intermediate distances, like reading a computer screen, while maintaining good distance…

This study compares two types of advanced lens implants (Clareon Vivity and PureSee) used in cataract surgery. Researchers want to see which lens provides better vision at far, intermediate, and near distances. The trial involves 80 adults aged 50 and older who need cataract surg…

This study investigates whether a small RNA molecule called tRF-31 is linked to the severity of age-related cataracts. Researchers will collect lens tissue from 200 adults undergoing routine cataract surgery and measure tRF-31 levels. The goal is to see if higher or lower levels …

This study screens people with eye diseases to see if they can join other research studies at the National Eye Institute. No treatment is given. Participants undergo eye exams, blood tests, and other procedures to diagnose or evaluate their condition. The goal is simply to determ…

This study looks at whether dry eye disease affects the accuracy of corneal measurements needed for cataract surgery planning. 400 cataract patients will be divided into those with and without dry eye. Those with dry eye will use sodium hyaluronate eye drops for two weeks. Resear…

This study tests a special camera that takes super-detailed pictures of the back of the eye (the retina). The goal is to see if this technology can find eye diseases earlier than standard methods. Up to 1,000 people aged 12 and older, with or without eye disease, will have their …

This study looks at 300 people having cataract surgery to see if where the surgeon places the phacoemulsification tip (the tool that breaks up the cataract) affects early healing. Researchers will use a special camera during surgery to track the tip's location and then measure co…

This study aims to learn more about eye diseases by observing and providing standard care to up to 1,000 people over 5 years. Participants receive regular eye exams, tests, and treatments as needed. The goal is to better understand how eye diseases progress and are inherited, not…

This study follows 60,000 people with cataracts, including those with high myopia (severe nearsightedness), to see how their vision changes after cataract surgery. Researchers will also look at genetic and environmental factors that might affect cataract development and surgical …

This study compares two different machines used during cataract surgery to see which one uses less ultrasound energy. The researchers will measure the total energy delivered into the eye while removing the cloudy lens. Thirty adults with cataracts in both eyes will take part, wit…

This study tracks 400 adults with cataracts to see how three different toric intraocular lenses rotate after surgery. Rotation is measured at several follow-up visits over three months. The goal is to find which lens stays most stable and help doctors choose the best option for e…

This study tests whether artificial intelligence can create simple summaries of eye doctor notes that are easier for patients to understand. About 460 English-speaking adults receiving eye care will get either standard notes or notes plus an AI-generated plain language summary. P…

This study tests a new 4D microscope-integrated OCT system for the first time in people during eye surgery. Researchers want to see if the system is easy to use, safe, and can clearly show eye structures. Five adults having eye surgery will take part. The goal is to improve imagi…

This study gathers standard eye movement and pupil data from 200 healthy volunteers, children, and people with eye or brain conditions using a VR headset called neos™. The headset shows images and tracks where participants look, how their pupils react, and how their eyes move. Th…

This study tests a new, more comfortable eye camera (WiSLO) designed for children and adults. Researchers want to see if it takes better pictures and is less bothersome than current cameras. About 42 people with or without eye disease will have their eyes photographed with both t…