Senile cataract
MONDO:0004847A cataract with no obvious cause occurring in persons over 50 years old.
51 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Could these eye drops replace cataract surgery?
Disease control ENROLLING_BY_INVITATIONThis study tests an experimental eye drop called ZOC2017217 in 40 people with age-related cataracts. Participants will use the drops twice a day for 24 weeks to see if it improves vision and lens clarity compared to a placebo. The goal is to find a non-surgical option for catarac…
Phase: PHASE2 • Sponsor: Ocusun Ophthalmic Pharmaceutical (Guangzhou) Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New lens aims to match top cataract implant in vision quality
Disease control OngoingThis study compares a new domestic trifocal lens (D615L) to the Zeiss AT LISA tri 839MP for people having cataract surgery. 90 adults with age-related cataracts will receive one of the two lenses and be followed for 6 months to measure vision at different distances. The goal is t…
Sponsor: Shanghai 10th People's Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New cataract lens aims to sharpen vision at Arm's length
Symptom relief ENROLLING_BY_INVITATIONThis study looks at how well a new type of lens, called Clareon TruPlus, helps people see clearly at intermediate distances (like a computer screen) after cataract surgery. About 50 adults with cataracts in both eyes will get this lens and be tested 12 weeks after surgery. The go…
Sponsor: Colvard Kandavel Eye Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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New study tests best lens combo for cataract surgery – could reduce glare and halos
Symptom relief ENROLLING_BY_INVITATIONThis study compares two types of artificial lens implants used in cataract surgery. Some patients will get a different lens in each eye, while others will get the same lens in both eyes. The goal is to see which approach gives better vision and causes fewer problems like glare, h…
Phase: NA • Sponsor: Brian Shafer • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Which training method produces better eye surgeons?
Knowledge-focused OngoingThis study compares two methods for teaching cataract surgery to ophthalmology residents. One group learns steps in the usual order, while the other learns easier steps first. Researchers will measure how well residents perform surgery and how often complications occur. The goal …
Phase: NA • Sponsor: Sohag University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Could your phone replace a Post-Surgery eye check?
Knowledge-focused ENROLLING_BY_INVITATIONThis study tests whether a smartphone app (WHOeyes) plus a symptom questionnaire can safely replace the standard in-clinic checkup one week after cataract surgery. About 334 people aged 50–80 with uncomplicated cataracts will either use the app at home or come to the clinic. The …
Phase: NA • Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Cataract surgery device showdown canceled before it began
Knowledge-focused TerminatedThis study aimed to compare two different surgical systems for cataract removal in adults with moderate to severe cataracts. The goal was to see which system was safer and more efficient. However, the study was withdrawn before any participants were enrolled, so no results are av…
Phase: NA • Sponsor: Alcon Research • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Cataract device safety tracked over 20 months in extension study
Knowledge-focused ENROLLING_BY_INVITATIONThis study follows 61 people who previously used the REVISYON SDS 100 device for mild-to-moderate cataract. Researchers will check for side effects and measure vision changes over about 20 months. No new treatment is given; the goal is to see if the device stays safe and works we…
Sponsor: Edinburgh Biosciences Ltd • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Free eye tests aim to catch vision loss early in harlem and washington heights
Knowledge-focused OngoingThis study offers free vision screenings to underserved adults over 40 living in affordable housing in Harlem and Washington Heights. The goal is to find eye problems like glaucoma, cataracts, and diabetic retinopathy early and connect people with follow-up care. About 749 partic…
Phase: NA • Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Could a common diabetes drug slow cataracts?
Knowledge-focused OngoingThis pilot study looks at whether metformin, a standard diabetes medicine, gets into the lens capsule of the eye and can slow the growth of lens cells that cause cataracts. Researchers will collect blood and lens tissue from 40 people with type 2 diabetes and age-related cataract…
Phase: NA • Sponsor: Vienna Institute for Research in Ocular Surgery • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:29 UTC