Could these eye drops replace cataract surgery?
NCT ID NCT07395986
First seen Jun 27, 2026 · Last updated Aug 12, 2026 · Updated 6 times
Summary
This study tests an experimental eye drop called ZOC2017217 in 40 people with age-related cataracts. Participants will use the drops twice a day for 24 weeks to see if it improves vision and lens clarity compared to a placebo. The goal is to find a non-surgical option for cataracts.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ZOC2017217 eye drops
- What this could lead to
- If successful, this could lead to a non-surgical treatment for age-related cataracts, potentially improving vision without the need for surgery.
- What could go wrong
- This is an early Phase 2 pilot study with only 40 participants, so results may not apply to everyone. The eye drops may not improve vision significantly, and there could be side effects like eye irritation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Advanced Vision Research Institute
Longmont, Colorado, 80503, United States
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Bergstrom Eye Research
Fargo, North Dakota, 58103, United States
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Catalina Eye
Tucson, Arizona, 85712, United States
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Cincinnati Eye Institute - Blue Ash
Blue Ash, Ohio, 45242, United States
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Clayton Eye Clinical Research, LLC
Morrow, Georgia, 30260, United States
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Cornea and Cataract Consultants of Arizona
Scottsdale, Arizona, 85255, United States
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East West Eye Institute - Torrance
Torrance, California, 90505, United States
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Erie Retina Research
Erie, Pennsylvania, 16505, United States
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Global Research Management
Glendale, California, 91204, United States
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ICON Eye Care
Grand Junction, Colorado, 81501, United States
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Inland Eye Specialists
Hemet, California, 92545, United States
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Levenson Eye Associates
Jacksonville, Florida, 32204, United States
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North Bay Eye Associates, Inc.
Petaluma, California, 94954, United States
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Oculus Research - Cary
Cary, North Carolina, 27518, United States
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R and R Eye Research, LLC
San Antonio, Texas, 78229, United States
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Rand Eye Institute
Deerfield Beach, Florida, 33064, United States
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Springfield Clinic
Springfield, Illinois, 62703, United States
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United Medical Research Institute
Inglewood, California, 90301, United States
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Valley Retina Institute P.A.
Laredo, Texas, 78041, United States
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Valley Retina Institute P.A.
McAllen, Texas, 78503, United States
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Verum Research
Eugene, Oregon, 97401, United States
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