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Senile cataract
MONDO:0004847A cataract with no obvious cause occurring in persons over 50 years old.
51 clinical trials for this condition and its sub-types.
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New lens implant shows promise for cataract patients
Disease control CompletedThis study tested a new lens called 621 in 105 adults having cataract surgery. The lens was implanted during standard surgery to replace the cloudy natural lens. Researchers checked how well patients could see 6 months after surgery and monitored for any safety issues. The goal w…
Phase: NA • Sponsor: Carl Zeiss Meditec AG • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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New lens aims to sharpen vision after cataract surgery
Disease control CompletedThis study tested a new type of artificial lens, called the AT ELANA 841P, for people having cataract surgery. 284 adults with cataracts in both eyes received either the new lens or a standard lens. Researchers measured how well patients could see at different distances and check…
Phase: NA • Sponsor: Carl Zeiss Meditec, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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New device aims to sharpen vision without surgery in cataract patients
Disease control CompletedThis study tested a device called REVISYON SDS 100 to see if it can safely improve vision in people with age-related cataracts without surgery. 114 adults with moderate cataracts used the device, and researchers measured changes in eyesight and cataract severity. The goal was to …
Phase: NA • Sponsor: Edinburgh Biosciences Ltd • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Warm compress device shows promise for dry eyes before cataract surgery
Symptom relief CompletedThis study tested whether using the Systane iLux device—which applies heat and pressure to the eyelids—before cataract surgery could improve dry eye symptoms. Thirty adults scheduled for cataract surgery received the treatment in one eye. Researchers measured changes in tear film…
Phase: NA • Sponsor: George Washington University • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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New lens offers sharper sight at every distance after cataract surgery
Symptom relief CompletedThis study tested three types of artificial lenses implanted during cataract surgery to see which gives the best vision at far, middle, and near distances. 197 people with cataracts in both eyes received one of the three lens types. The goal was to improve vision and reduce the n…
Sponsor: Sakarya Yenikent State Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Eye drops may ease pain in second cataract surgery
Symptom relief CompletedThis study tested whether anti-inflammatory eye drops (pranoprofen or prednisolone acetate) can reduce pain during second-eye cataract surgery compared to standard lubricating drops. 126 adults aged 50 and older who had already had one cataract surgery received the drops before t…
Phase: PHASE4 • Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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New eye gel passes safety test in cataract surgery trial
Symptom relief CompletedThis study tested a new gel called PRO-149 used during cataract surgery to protect the eye. 36 adults with age-related cataracts received either the new gel or a standard gel during their operation. The main goal was to check safety by measuring changes in eye cell count and pres…
Phase: NA • Sponsor: Laboratorios Sophia S.A de C.V. • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Which eye scanner is best for cataract surgery? new study puts two devices to the test
Knowledge-focused CompletedThis study compared two devices that measure the eye before cataract surgery to help pick the right lens implant. 144 Thai adults had both measurements taken on the same day. The goal was to see which device more accurately predicted the patient's vision one month after surgery.
Phase: NA • Sponsor: Walailak University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Eye muscle measurements may flag risky cataract surgeries
Knowledge-focused CompletedThis study looked at 30 men taking alpha-blocker drugs for urinary symptoms who were scheduled for cataract surgery. Researchers used a special eye scan to measure the thickness of iris muscles and pupil size. The goal was to see if these measurements could predict intraoperative…
Sponsor: University Hospital Olomouc • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Eye fluid analysis may predict Post-Surgery dry eye
Knowledge-focused CompletedThis study analyzed tear and eye fluid samples from 100 cataract surgery patients to find biomarkers that could predict dry eye disease after surgery. Researchers used advanced chemical analysis to look for clues in the eye's surface cells and inner fluid. The goal is to better u…
Phase: NA • Sponsor: University Hospital, Tours • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Diabetes may worsen eye cell loss after cataract surgery, study finds
Knowledge-focused CompletedThis study looked at 100 people aged 40 and older who had cataract surgery. Half had type 2 diabetes and half did not. Researchers measured changes in the thin cell layer on the inside of the cornea before and after surgery to see if diabetes affects recovery. The goal is to help…
Phase: NA • Sponsor: Al-Azhar University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Cataract lens still clear after 2 years? study checks for glistening
Knowledge-focused CompletedThis study checked how well a specific intraocular lens (CT LUCIA 621P) holds up at least two years after cataract surgery. Researchers looked for tiny fluid-filled bubbles called glistening and measured vision in 33 patients. The goal was to see if the lens remains safe and clea…
Sponsor: Carl Zeiss Meditec AG • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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AI eye chatbot matches doctors in taking patient history
Knowledge-focused CompletedThis study tested whether a large language model (like ChatGPT) could collect medical history and suggest eye tests as well as doctors do. 172 patients with non-emergency eye problems took part. The AI's performance was compared to standard care, with senior specialists checking …
Phase: NA • Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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New lens design aims for better stability after cataract surgery
Knowledge-focused CompletedThis study tested a new type of artificial lens (HOYA AF-1 NY-60) used during cataract surgery. The lens is designed to stay in place better and reduce clouding behind the lens. Researchers looked at how well the lens performed in 42 people with normal, short, or long eyes. The s…
Phase: NA • Sponsor: Vienna Institute for Research in Ocular Surgery • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC