Hidden risks for Women's eye surgery: floppy iris syndrome under the microscope

NCT ID NCT07687407

Completed Knowledge-focused Sponsor: Başakşehir Çam & Sakura City Hospital Source: ClinicalTrials.gov ↗

First seen Jul 07, 2026 · Last updated Jul 09, 2026 · Updated 2 times

Summary

This study looks at why some women develop a condition called Intraoperative Floppy Iris Syndrome (IFIS) during cataract surgery. IFIS makes the iris unstable, complicating surgery and raising risks. Researchers are examining factors beyond medication—such as medical history and prior surgeries—that may increase risk in women aged 50 and older. The goal is to better predict and prevent this complication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help identify women at higher risk for floppy iris during cataract surgery, allowing surgeons to take extra precautions.
What could go wrong: This is an observational study, not a treatment trial. It may find associations but cannot prove cause and effect.

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Conditions

The condition(s) this trial relates to.

cataract intraoperative floppy iris syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INTRAOPERATIVE FLOPPY IRIS SYNDROME

Contacts and locations

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Locations

Başakşehir Çam and Sakura City Hospital

Istanbul, 34, Turkey (Türkiye)

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