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Can a steroid outperform a standard antiemetic to stop Post-Surgery sickness?

NCT ID NCT07086118

Symptom relief Sponsor: Alexandria University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 24, 2026 · Last updated Aug 25, 2026 · Updated 1 time

Summary

This trial tests whether a single dose of dexamethasone, a steroid, can prevent nausea and vomiting after cataract surgery better than metoclopramide, a standard antiemetic. About 210 adults aged 40-80 undergoing cataract surgery will receive one of the two drugs or a placebo before the procedure. The goal is to see if dexamethasone reduces the number of patients who feel sick afterward, which could improve recovery and lower the risk of serious eye complications.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dexamethasone and metoclopramide
What this could lead to
If dexamethasone works better, it could offer a simple way to prevent post-surgery nausea and vomiting, improving patient comfort and reducing rare but serious eye complications.
What could go wrong
This is a single trial with 210 participants, so results may not apply to everyone. Both drugs have side effects, and dexamethasone may not prove superior to the standard treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

210 people

The number who actually took part.

Started

May 2025

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age: 40-80 years, both sexes. * ASA physical status class I to III. Exclusion Criteria: * history of motion sickness * patients with gastrointestinal disorders or gastro-oesophageal reflux * patients taking medications with known antiemetic activity * previous postoperative vomiting * allergy to bupivacaine * allergy to metoclopramide or dexamethasone

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Conditions

The condition(s) this trial relates to.

cataract

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cataract Dexamethasone

Contacts and locations

Locations

  • Alexandria University

    Alexandria, Egypt

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