CATARACT

This study tests a tiny implant that releases medication to lower eye pressure in people with glaucoma or high eye pressure who are also having cataract surgery. About 400 participants will receive either the implant during surgery or standard eye drops. The goal is to see if the…

This study is checking the safety of the IC-8 Apthera lens implant after treating a common side effect called posterior capsule opacification (PCO), where the lens capsule becomes cloudy. About 435 adults who already have this lens and develop PCO will be followed for up to 2 yea…

This study compares two different trifocal toric lens implants used during cataract surgery to correct cataracts, astigmatism, and presbyopia (difficulty seeing up close). About 138 adults with regular corneal astigmatism will receive one of the two lenses. The main goal is to se…

This study tests a special cleaning tool, called the Tran cannula, during cataract surgery for people with a type of glaucoma linked to flaky material in the eye. The goal is to see if it lowers eye pressure better than simply using more fluid to wash the eye. About 58 adults wil…

This study tests whether special eye drops made with stem cells can help people with dry eye disease and cataracts. The drops aim to reduce inflammation and repair the eye's surface. About 300 adults aged 18 to 80 will take part. The study will check if the drops improve tear fil…

This study tests a tiny implant that releases medication to lower eye pressure in people with glaucoma or high eye pressure who are also having cataract surgery. About 400 participants will receive either the implant during surgery or standard eye drops. The goal is to see if the…

This study tests a vision screening program in Danish general practice for people over 70 with at least one chronic condition. The goal is to see if the screening can catch vision problems early and refer patients to eye specialists. About 460 participants will be recruited, and …

This study looks at whether placing a small support ring (capsular tension ring) during cataract surgery helps keep the artificial lens more stable in people who also have retinitis pigmentosa (RP). Each of the 88 participants will get the ring in one eye only, so the other eye s…

This study looks at whether a multimedia education program (like videos and interactive materials) can reduce anxiety and improve self-care knowledge in people having cataract surgery. About 118 adults will be randomly assigned to receive either standard instructions or the multi…

This study tests a new robotic system called ORYOM to help surgeons perform cataract surgery. About 20 people aged 55 to 80 who need cataract surgery will take part. The main goal is to see if the robot can safely complete the surgery without switching to a manual method.

This early-stage study tests the safety of an eye injection called EO2002 given during cataract surgery. It is for adults with cataracts and low corneal cell counts. The main goal is to see if the treatment is safe and well-tolerated.

This study compares two types of advanced lens implants used during cataract surgery: Clareon Vivity and PureSee. The goal is to see which lens provides better vision at different distances (near, far, and in between). Eighty adults aged 50 and older who need cataract surgery in …

This study looks at how well a new type of artificial lens (Clareon PanOptix Pro) works for people who have had LASIK or PRK surgery for nearsightedness and now need cataract surgery. About 40 adults aged 45 and older will get the lens in both eyes. Researchers will check their v…

This study tests whether a medication given as a nose spray (dexmedetomidine) can help keep blood pressure stable in older adults with high blood pressure who are having cataract surgery. About 126 people aged 65 and older will take part. The goal is to see if the spray reduces d…

This study compares three sedation methods (dexmedetomidine, propofol, or both) in 1,000 adults having cataract surgery. The goal is to see which approach provides the best sedation with the fewest side effects like low blood pressure or nausea. All participants will also receive…

This study tests a special lens for cataract surgery in 30 people aged 50+ who previously had LASIK for nearsightedness. The lens aims to improve vision at all distances and boost satisfaction. Researchers will measure how well patients see and how often they need glasses after s…

This study compares two types of special lenses (Rayone EMV and Vivinex Impress XY1-EM) implanted during cataract surgery to see which provides better vision at intermediate distances, like arm's length. About 100 adults with age-related cataracts will receive both lenses (one in…

This study tests whether keeping the eye at a lower pressure during cataract surgery leads to less swelling and clearer vision right after the procedure. About 105 people having cataract surgery will get a different pressure level in each eye. Both surgical systems used are alrea…

This study looks at a new dual-mode phacoemulsification system used during cataract surgery. Researchers want to see if it reduces surgery time and damage to the eye's inner lining. About 50 adults having age-related cataract surgery will take part. They will be checked 3 months …

This study looks at how general anesthesia changes blood pressure and eye pressure in people aged 65-85 having cataract surgery. Researchers will also check if a patient's frailty level is linked to these changes. The goal is to better understand risks for older patients during s…

This study tests whether surgeons can safely use an Apple Vision Pro headset during cataract and other eye surgeries. About 30 adults having elective eye surgery will take part. The goal is to see if the headset improves the surgeon's view and comfort without causing complication…

This study aims to understand how well people with high myopia (severe nearsightedness) see after cataract surgery, and what genetic or environmental factors affect their results. Researchers will compare 60,000 patients with high myopia, age-related cataracts, or other vision pr…

This study compares three AI chatbots (ChatGPT 4o, GPT-5, and DeepSeek) to see how well they can read eye scan reports and recommend the right lens for cataract surgery. Researchers will check if the AI's predictions match those of eye doctors. No patients receive any treatment—i…

This study collects information from 300 people who have had or will have cataract surgery with one of three lens types. The goal is to compare how well people see at different distances after surgery. No new treatments are being tested—just observing and recording outcomes.

This study compares two different surgical systems used during combined cataract and vitrectomy surgeries. Researchers will measure how efficient each system is, including setup and teardown time, and ask surgeons to rate their experience. The goal is to see which system works be…

This study looks at how three different toric intraocular lenses (special lenses that correct astigmatism) rotate after cataract surgery. Researchers will track 400 adults who need cataract surgery and a toric lens, measuring lens rotation at several follow-up visits over three m…

This study looks at fluid and tissue samples from the eyes of people with glaucoma and cataracts, and compares them to samples from cataract patients without glaucoma. The goal is to find unique molecular patterns linked to glaucoma that could lead to better diagnosis or monitori…

This study looks at 90 cataract patients who also have an epiretinal membrane (a thin scar on the retina). Researchers want to see if a special "functional" lens implant helps vision more than a standard lens. Participants will have their vision tested before and after surgery to…

This study looks at how fluid drains from the eye during cataract or glaucoma surgery. By measuring eye pressure during the operation, doctors hope to better predict and improve recovery. About 150 adults having surgery at Mount Sinai will take part.

This study compares newer laser techniques for cataract or nearsightedness surgery to see which one reduces inflammation and helps eyes heal better. Researchers will measure natural antioxidants in tears and eye fluid before and after surgery in 1000 adults. The goal is to find o…

This study tests a new microscope that shows live 3D images inside the eye during surgery. It includes up to 262 people with various eye conditions like retinal detachment, cataracts, or macular holes, as well as healthy volunteers. The goal is to see if this technology helps sur…

This study looks at how different types of lens implants used in cataract surgery affect vision quality. Researchers will use special eye scans to measure the internal optics of the eye in 80 adults who have already had cataract surgery. The goal is to understand which lens desig…

This study collects detailed eye measurements from 400 people with cataracts using a new device called Unity DX. The goal is to gather data to improve future cataract surgery planning. No treatment or medication is given—just measurements during a single visit.