OBESITY & OVERWEIGHT

This study looked at how the drug tirzepatide works in real-world settings for two groups: people who regained weight after bariatric surgery and people with obesity preparing for surgery. Researchers tracked weight and health changes over six months in 254 adults. The goal was t…

This study tested a daily injection called ROSE-010 in 40 overweight or obese women to see if it reduces how much they eat at lunch. The drug is similar to natural hormones that control appetite. The goal is to help manage weight by curbing hunger and increasing fullness.

This study looked at how well adults with obesity or complicated overweight follow and tolerate different very-low-calorie ketogenic diets. Participants chose one of four diet plans, ranging from natural foods to meal replacements, and were followed for about 26 weeks. The goal w…

This study tested a web-based tool called WeDosify that helps doctors manage dosing of the weight-loss drug semaglutide for adults with overweight or obesity. Twenty participants who had recently started semaglutide used the tool over three months. The main goal was to see if the…

This study tested whether personalized diet advice based on a person's gut bacteria could help adults with obesity make healthier food choices and improve gut health. Fifty participants in Colombia were split into two groups and followed for 12 weeks. Researchers measured changes…

This study looked at whether intermittent fasting or a Mediterranean diet helps overweight and obese adults lose weight and improve body composition. About 100 people took part. Researchers measured changes in body fat, weight, and nutrition knowledge to see which approach worked…

This study tested a very low-calorie ketogenic diet (VLCKD) in 17 adults with obesity to see how it changes body weight and energy use over 24 hours. Participants followed the diet for a set period, and researchers measured their body composition and metabolism. The goal was to u…

This study looked at whether weight-loss surgery (laparoscopic sleeve gastrectomy) helps adults over 65 with severe obesity and related conditions like type 2 diabetes, high blood pressure, sleep apnea, or knee arthritis. Sixty patients chose either surgery or standard care (diet…

This study looked at whether adding a protein supplement to a small meal on fasting days helps young men with overweight lose body fat while preserving muscle. Twenty-six men aged 21 to 35 followed a 4-week alternate-day fasting plan. One group ate a small meal with a protein sha…

This study tested a 12-week diet and lifestyle program called the SWW Method in 85 women aged 35-75. The program included intermittent fasting, a high-protein diet, and other healthy habits. Researchers measured changes in blood sugar (HbA1c), weight, and body mass index (BMI) co…

This study looked at whether taking Korean ginseng extract for eight weeks could help healthy adults feel less tired and improve their exercise performance. Sixty adults aged 20 to 50 took either the ginseng extract or a placebo daily. Researchers measured changes in strength, ox…

This study tested whether special food supplement capsules that release nutrients in the lower gut can increase appetite-regulating hormones and reduce food intake. Twenty adults with obesity took either the active supplement or a placebo on two separate days. Researchers measure…

This study looked at whether changing how often women eat (meal frequency) can improve their confidence in sticking to a diet and reduce stress. 72 women aged 25-55 with a history of weight cycling (repeated weight loss and regain) and a BMI between 25-35 took part. The goal was …

This study looked at whether teaching mindful eating skills to adults with obesity can reduce hedonic hunger—the desire to eat for pleasure rather than hunger. 82 participants either followed a weight-loss diet alone or added mindful eating training. Researchers measured changes …

This small study tested whether gummy candies made with maqui berry could help overweight adults control their blood sugar after eating a carb-rich meal. Ten participants ate white bread alone or with the maqui gummies on separate days, and their blood sugar and antioxidant level…

This study tested a new 'hook technique' for one-hand mask ventilation in 375 obese adults (BMI 30-40). The goal was to see if it works better than traditional methods for getting air into the lungs during procedures. Researchers measured chest rise, oxygen levels, and other brea…

This study tested whether a dietary supplement called NatureU Burn can help healthy adults feel fuller after a meal. Fourteen people took either glucose alone or glucose plus the supplement, then rated their fullness and hunger over four hours. The goal was to see if the suppleme…

This study looked at whether standing on a vibrating platform while doing foot exercises could help overweight and obese young adults (ages 18-35) improve ankle strength, balance, and body awareness. Twenty-six people completed 24 supervised sessions over 8 weeks. The results may…

This early-stage study tested whether a new probiotic bacterium, Phascolarctobacterium faecium, is safe and well-tolerated in 20 adults, including healthy-weight individuals and those with overweight or early blood sugar issues. Participants took the bacterium daily for 15 days a…

This study looked at whether adding TECAR therapy or shock wave therapy to standard lymphedema care helps reduce leg swelling in severely obese women. Forty-five women received either standard care alone or combined with one of the two extra treatments over four weeks. Researcher…

This study looked at over 450,000 adults with obesity and type 2 diabetes who were already taking a GLP-1 or SGLT2 drug. Researchers compared what happened when they added another diabetes medicine early (within 90 days) versus not adding one. The goal was to see if early add-on …

This study looked at whether a simple CT scan before weight-loss surgery can help predict when the surgeon might need to change their plan during the operation. Researchers reviewed data from 288 patients who had surgery for obesity. They found that certain measurements from the …

This study examined if the type of diabetes medication taken before a cancer diagnosis affects survival and complications after cancer in adults with obesity and type 2 diabetes. Researchers analyzed health records from over 200,000 people, comparing those who used GLP-1 receptor…

This study looked at over 11,500 adults with overweight or obesity who used a breath-biofeedback mobile health program called Key to Health. Researchers wanted to see how much weight people lost and kept off after two years of using the app. The study did not test a new treatment…

This study looked at how walking exercise and changes in body fat relate to brain structure in 22 overweight adults with headaches. Participants either followed a diet plus a 12-week walking program or diet alone. Brain scans and body fat measurements were taken before and after …

This study followed 22 adults with obesity who underwent a standard diet and lifestyle program to lose weight. Researchers measured weight loss, body fat distribution, and metabolic changes over 12 months. The goal was to better understand how the body adapts during weight loss, …

This study looked at two weight-loss medicines, cagrilintide and semaglutide, given either together in one injection or as two separate shots. The goal was to see how the different methods affect medicine levels in the blood. Forty adults with overweight or obesity received weekl…

This study looked at 821 first-year university students in Spain to understand how their physical activity and sitting habits relate to obesity and muscle/joint health risks. Researchers used questionnaires to measure activity levels and body mass index (BMI) to classify weight. …

This study looked at 40 severely obese adults who had laparoscopic sleeve gastrectomy, a type of weight-loss surgery. Researchers measured blood levels of isthmin, a hormone made by fat tissue, before and after surgery to see if it changes. The goal is to better understand how th…

This study tested whether adding moderate aerobic exercise to Ramadan fasting helps overweight adults lose more body fat and improve heart health markers. 28 participants were split into two groups: one fasting only, the other fasting plus supervised exercise. Researchers measure…

This completed Phase 1 study tested a single injection of petrelintide, a drug being developed for weight management, in 48 adults with a BMI of 27 or higher. The goal was to see if different concentrations of the same dose change how the body absorbs and processes the drug, and …

This study looked at how a single dose of the experimental drug VCT220 behaves in 16 people with moderate kidney problems compared to 16 people with normal kidneys. The goal was to see if kidney function changes drug levels and safety. Results will help doctors decide the right d…

This study looked at 150 adults with normal weight, overweight, or obesity to see if a nutrition plan based on both genes and body measurements works better than one based only on body measurements. Participants followed a six-month diet plan, and researchers tracked changes in w…

This study tested whether two different doses of dietary supplements (DIM and Perilla oil) delivered to the lower gut could reduce appetite and food intake in 16 adults with obesity. Participants fasted, took capsules, and had blood drawn every 30 minutes to measure hunger hormon…

This study looked at how sleep quality, when people eat, and gut bacteria are connected to obesity. It included 133 adults with different body weights and sleep issues. The goal was to understand these links and test a simple e-health tool to help people make healthier lifestyle …

This study looked at how losing at least 10% of body weight changes the heart's shape and function in people who are overweight or obese and have heart risk factors. Researchers used heart scans and blood tests to measure these changes. The goal was to understand if weight loss c…