Gut check: do supplements curb hunger?
NCT ID NCT07491835
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether two different doses of dietary supplements (DIM and Perilla oil) delivered to the lower gut can reduce appetite and food intake in adults with obesity. Sixteen participants fasted, took capsules, and had blood tests and hunger ratings over 8 hours. The goal was to see how these nutrients affect appetite-regulating hormones and eating behavior.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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16 people
The number who actually took part.
- Started
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Oct 2023
- Finished
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Nov 2023
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged 18 years or over * BMI 30-40 kg/m² * No prior bowel surgery * Not taking medications for Type II diabetes * Willing to consume standardised test meals * Able to understand the study information sheet and instructions in English * Able to provide written informed consent Exclusion Criteria: * BMI outside the range of 30-40 kg/m² * Major gut surgery involving removal of any part of the gastrointestinal tract * Known major bowel disease * Currently taking medication for Type 1 or Type 2 diabetes * Currently taking medication for weight loss (e.g., semaglutide) * Unable to understand English or provide informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Wingate Institute of Neurogastroenterology
London, E1 2AJ, United Kingdom
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Other studies related to the condition(s) this trial covers.
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