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Religious fasting twice a week could reshape gut health and curb appetite in obesity

NCT ID NCT07703865

Disease control Sponsor: University of Muhammadiyah Jakarta Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This study looks at whether a traditional Islamic practice—fasting from dawn to sunset every Monday and Thursday for 8 weeks—can improve gut health, appetite control, and body composition in obese adult men. Participants follow the fast without any other diet changes, while researchers measure gut bacteria byproducts, hunger hormones, and body fat. The goal is to see if this culturally rooted fasting pattern offers health benefits beyond weight loss alone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Monday-Thursday Sunnah dry fasting (no food or water from dawn to sunset, ~13 hours, twice weekly for 8 weeks)
What this could lead to
If effective, this religiously motivated fasting pattern could offer a sustainable, culturally acceptable way to improve gut health and manage weight in obese men.
What could go wrong
This is a small, early study without blinding or randomization, so results may not be reliable or generalizable. The dry fasting may also pose risks like dehydration or electrolyte imbalance.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

74 people

The number who actually took part.

Started

Sep 2025

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

19 years and older

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male, age ≥ 19 years * BMI ≥ 25 kg/m² (Asia-Pacific obesity criteria) * Waist circumference \> 90 cm * No regular intermittent fasting practice in the prior month * No antibiotic use in the prior month * Not currently enrolled in any dietary or weight loss program * Muslim and willing to perform Monday-Thursday Sunnah fasting * Residing in DKI Jakarta and surrounding areas (Bogor, Depok, Tangerang) Exclusion Criteria: * Diagnosed type 2 diabetes mellitus on oral antidiabetic agents, insulin, or GLP-1 receptor agonists * Coronary heart disease * Chronic kidney disease * Uncontrolled hypertension * Regular use of probiotics, prebiotics, fiber supplements, omega-3, or herbal supplements * Regular use of lipid-lowering agents, orlistat, appetite suppressants, or hormonal medications * Excessive alcohol consumption * Vegetarian diet * Active smoker

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Conditions

The condition(s) this trial relates to.

Intermittent Fasting Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Gut microbiota Obesity / overweight

Contacts and locations

Locations

  • Faculty of Medicine and Health, Universitas Muhammadiyah Jakarta

    South Tangerang, Banten, 15419, Indonesia

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