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Protein powder during fasting may save your muscles while you shed pounds

NCT ID NCT07241689

Disease control Sponsor: Nanyang Technological University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether taking a protein supplement on fasting days during a 4-week alternate-day fasting program could help young men with overweight lose fat while keeping muscle. Twenty-six men aged 21 to 35 either ate a small meal (400-600 kcal) or the same meal plus a whey protein shake on fasting days. Researchers measured body composition, blood sugar, and blood pressure before and after the program.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
whey protein powder (25 g protein, 125 kcal)
What this could lead to
If it works, this could point toward a way to lose weight while preserving muscle, which may help manage obesity.
What could go wrong
This is a small, early study with only 26 young men, so results may not apply to others. The fasting regimen is strict and may be hard to follow long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

26 people

The number who actually took part.

Started

Jan 2018

Finished

Mar 2018

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 35 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male * 21 to 35 years old * Do not smoke or use tobacco products (including shisha) * Have a body mass index (BMI = body mass in kilograms divided by the square of height in metres) of 23 or greater Exclusion Criteria: One cannot participate in or will be released from this study if any of the following conditions or situations applies to them: * Unable to adhere to requirements regarding physical activity and diet as stated in the methods * Failed an exercise stress test * Have any health condition(s) that would be made worse by fasting * Taking long-term prescribed medication(s) for heart, blood (including blood glucose and blood pressure), lung (except controlled asthma), liver, kidney or joint condition(s) * Taking other long-term prescribed medication (including traditional Chinese Medicine and other alternative medicine) that are known to affect any of the measurements in this study * Allergic or intolerant to milk and soy (the protein supplement that participant may be required to consume, contains milk proteins and traces of soy lecithin and lactose) * Have an artificial electrical implant such as a defibrillator or pacemaker

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Conditions

The condition(s) this trial relates to.

Intermittent Fasting Obesity obesity disorder Overweight platelet-type bleeding disorder 10 Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Obesity & overweight

Contacts and locations

Locations

  • Nanyang Technological University

    Singapore, Singapore

More trials for these conditions

Other studies related to the condition(s) this trial covers.