Scientists track inflammation marker after sleeve gastrectomy
NCT ID NCT07655739
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at 40 adults who had sleeve gastrectomy surgery for obesity. Researchers measured blood levels of fractalkine, a protein involved in inflammation, before and three months after surgery. The goal was to see how fractalkine levels change and whether those changes relate to how much weight people lose.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help explain how weight loss surgery reduces inflammation and improve understanding of obesity.
- What could go wrong
- This is a small, completed observational study with only 40 participants. Results may not apply to everyone and do not test a new treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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40 people
The number who actually took part.
- Started
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Sep 2025
- Finished
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Feb 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with a body mass index (BMI) ≥40 kg/m² or a BMI ≥35 kg/m² in the presence of at least one obesity-related comorbidity who were planned for Laparoscopic Sleeve Gastrectomy.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * • Age ≥18 years * • Elective laparoscopic sleeve gastrectomy * • Provision of written informed consent for study participation and scheduled follow-up assessments Exclusion Criteria: * • Active infection or acute inflammatory condition * • Autoimmune or chronic inflammatory disease * • History of malignancy * • Chronic liver or kidney disease * • Pregnancy or lactation * • Corticosteroid or immunosuppressive therapy * • Major postoperative complications * • Missing data or incomplete sampling
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Elazig Fethi Sekin City Hospital
Elâzığ, 23100, Turkey (Türkiye)
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