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Scientists track inflammation marker after sleeve gastrectomy

NCT ID NCT07655739

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 40 adults who had sleeve gastrectomy surgery for obesity. Researchers measured blood levels of fractalkine, a protein involved in inflammation, before and three months after surgery. The goal was to see how fractalkine levels change and whether those changes relate to how much weight people lose.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help explain how weight loss surgery reduces inflammation and improve understanding of obesity.
What could go wrong
This is a small, completed observational study with only 40 participants. Results may not apply to everyone and do not test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

40 people

The number who actually took part.

Started

Sep 2025

Finished

Feb 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with a body mass index (BMI) ≥40 kg/m² or a BMI ≥35 kg/m² in the presence of at least one obesity-related comorbidity who were planned for Laparoscopic Sleeve Gastrectomy.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * • Age ≥18 years * • Elective laparoscopic sleeve gastrectomy * • Provision of written informed consent for study participation and scheduled follow-up assessments Exclusion Criteria: * • Active infection or acute inflammatory condition * • Autoimmune or chronic inflammatory disease * • History of malignancy * • Chronic liver or kidney disease * • Pregnancy or lactation * • Corticosteroid or immunosuppressive therapy * • Major postoperative complications * • Missing data or incomplete sampling

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Conditions

The condition(s) this trial relates to.

Inflammation morbid obesity Obesity obesity disorder Overweight Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Elazig Fethi Sekin City Hospital

    Elâzığ, 23100, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.