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Shedding light on a Fat-Related protein after stomach surgery

NCT ID NCT07335549

Knowledge-focused Sponsor: Saglik Bilimleri Universitesi Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 40 people with severe obesity who had laparoscopic sleeve gastrectomy, a type of weight-loss surgery. Researchers measured levels of a protein called isthmin in the blood before surgery and three months after. The goal was to see if isthmin, which is linked to metabolism and appetite, changes after significant weight loss. The study is purely observational and does not test any drug or treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could clarify how isthmin levels change after weight-loss surgery, pointing toward new ways to understand or treat obesity-related metabolic issues.
What could go wrong
This is a small, completed observational study with only 40 participants. It measures a biomarker (isthmin) and does not test a treatment, so it cannot directly lead to a therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

40 people

The number who actually took part.

Started

Jul 2025

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

BMI \> 40 kg/m2 without comorbidity who are planned for Laparoscopic Sleeve Gastrectomy

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Being over 18 years of age * Being diagnosed with severe obesity * Patients who do not wish to participate in the study Exclusion Criteria: * Patients under 18 years of age * Overweight patients with a Body Mass Index \<40 kg/m2 and no comorbidities * Patients with rheumatological diseases (rheumatoid arthritis, SLE, etc.) * Patients with chronic kidney and liver failure * Patients diagnosed with Diabetes Mellitus * Patients with malignancy * Patients who do not wish to participate in the study

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Conditions

The condition(s) this trial relates to.

morbid obesity Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Adipokines Obesity & overweight Sleeve gastrectomy

Contacts and locations

Locations

  • Elazig Fethi Sekin City Hospital

    Elâzığ, 23100, Turkey (Türkiye)

More trials for these conditions

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