DIABETES

This study tested whether the pill glyburide works as well as insulin shots for managing gestational diabetes in pregnant women. Over 900 women participated, and researchers looked at baby health issues like high birth weight, low blood sugar, and jaundice. The goal was to see if…

This study tested whether a personalized lifestyle program could help people with insulin resistance, obesity, diabetes, high blood pressure, or high cholesterol. Forty adults from a family medicine clinic were first assigned to either nutrition counseling or exercise counseling.…

This study tested a program to help South Asian adults with uncontrolled diabetes lower their blood sugar. The program used health coaches, a patient registry, and referrals to community resources. 859 participants were followed for 6 months to see if their HbA1c levels dropped b…

This study looked at whether getting blood sugar under control for a short time before major abdominal surgery can lower the risk of problems or death in adults with uncontrolled diabetes. 53 people took part. The goal was to see if this approach helps them spend more days at hom…

This study tested whether bringing HIV and chronic disease care into the community and linking it with microfinance groups helps people stay in care and keep the virus under control. About 1,200 adults with HIV in rural Kenya took part. The goal was to see if easier access to car…

This study looked at whether treating gum disease (periodontitis) can improve blood sugar control in adults with diabetes. 91 participants were randomly assigned to receive either gum treatment right away or after the study ended. The main goal was to see if the treatment lowered…

This study tested a healthy eating and exercise program to help people with early Type 2 diabetes achieve remission. 35 adults with diabetes and overweight participated, with some getting the program and others receiving usual care. The goal was to see if the program could lead t…

This study tested a program called Family Check-Up Heart for new moms and their babies. The goal was to help moms improve their heart health after pregnancy by managing weight and other risks. About 117 moms who were eligible for Medicaid took part. The program added heart-health…

This study tested two drugs—hydralazine-ISDN and metformin—in 1,100 people with chronic heart failure and reduced heart function. The goal was to see if these drugs could lower the risk of death or hospital stays due to worsening heart failure. Participants took either the study …

This study tested a fully automated system that delivers both insulin and glucagon to manage blood sugar in adults with type 1 diabetes. Over 12 months, 243 participants used the dual-hormone closed loop system or standard care. The goal was to see if this approach improves time …

This study tested a new wearable device that measures blood sugar continuously for up to 5 days in 247 adults with diabetes. Participants wore the sensor and a standard monitor while checking their blood sugar with fingersticks. The goal was to see if the new sensor is safe and a…

This study tested whether a program of diet, aerobic exercise, and balance training could improve nerve function and balance in people with prediabetes or early type 2 diabetes. About 61 participants were assigned to either the program or standard care. The goal was to see if the…

This study tested a new method to diagnose diabetes using a special laser technique called SERS, combined with gold nanoparticles and machine learning. Researchers analyzed blood samples from 52 adults (both healthy and with confirmed diabetes) to see if the technique could tell …

This study tested a new automated screening tool called OPTDR01 to detect diabetic retinopathy, a leading cause of vision loss, in people with diabetes. The tool is designed for use in primary care settings to make screening more accessible, especially for underserved groups. Res…

This study tested a program that gives free healthy food to people at risk for diabetes. The goal was to help them stick with a diabetes prevention plan and make lasting changes to their diet and lifestyle. 61 adults with high blood sugar took part. Researchers tracked how many c…

This study tested a new method called inforatio to help heal diabetic foot ulcers. Doctors made tiny cuts in the wound to trigger the body's natural healing response. 100 adults with diabetes took part. The goal was to see if this technique helps ulcers heal completely.

This pilot study tested whether a 12-week foot-ankle exercise program is better than walking for adults with type 2 diabetes. The goal was to see if it could help with nerve pain, stress, and quality of life. 108 people took part, and the study focused on whether such a larger tr…

This study tested whether the drug acarbose, adjusted using continuous glucose monitoring (CGM), can reduce pain in adults with painful diabetic neuropathy and unstable blood sugar. 170 participants used a CGM device and took acarbose or a placebo for 4 weeks. The goal was to see…

This study looked at whether quercetin, a natural substance found in foods like onions and apples, can change how the body absorbs sugar. Researchers gave 24 adults with obesity or obesity plus type 2 diabetes either quercetin or a placebo during a sugar-drink test. They measured…

This study looked at how lifestyle changes like diet and exercise affect blood sugar in 61 adults with diabetes. Researchers used advanced tests (genomics, proteomics, metabolomics, microbiomics) to find the key biological pathways involved. The goal was to build a model that cou…

This pilot study tested whether combining health information technology with practice facilitation (coaching) helps clinics refer more people with diabetes to diabetes self-management education and services (DSMES). The study involved 22 clinics and measured referral and attendan…

This study tested a 12-week program where people with overweight or obesity who were already taking weight-loss medication (GLP-1s) used a Fitbit and worked with a health coach. The goal was to see if this approach could help them become more active and improve their health. The …

This study checked whether acetaminophen (Tylenol) interferes with a new type of continuous glucose monitor worn under the skin. 31 adults with diabetes wore the device for three days and took the painkiller on the last day. Researchers compared the sensor's readings to standard …

This study looked at how vitamin E is absorbed and used by women who are normal weight, overweight, or have type 2 diabetes. Researchers measured vitamin E levels in blood and tissues after meals with different amounts of fat and vitamin E. The goal was to understand how much vit…

This study looked at whether teaching mothers about their family's health history (like heart disease, diabetes, and cancer) could help them encourage healthier eating and exercise in their families. About 310 adults took part, completing surveys and using a special tool to learn…

This study looked at how different diets affect the number of calories people burn and their risk for diseases like diabetes and heart problems after losing weight. About 234 adults with overweight or obesity took part. Researchers measured total calories burned using special wat…

This pilot study tested whether continuous glucose monitors (CGMs) can help track blood sugar levels in hospitalized adults with diabetes. Forty patients wore a CGM device during their hospital stay to see if it could catch dangerous highs and lows better than standard checks. Th…

This study looked at how eating a high fat diet for just 5 days affects the way muscles use sugar and fat. The researchers studied 11 healthy, non-obese men to see if a high fat diet causes muscle to become less flexible in handling energy sources, similar to what is seen in peop…

This study examined 200 patients who had surgery to remove plaque from their carotid arteries. Researchers identified bacteria living inside the plaques and tracked whether certain bacteria were linked to complications like stroke or re-narrowing of the artery. The goal was to le…

This study examined whether viral infections and diabetes during pregnancy increase the risk of congenital heart defects in babies. Researchers analyzed blood and stool samples from 114 women to detect viruses and immune responses. The goal was to gather knowledge for future larg…

This study followed 514 people with stable coronary artery disease for 18 months. Researchers measured how well their bodies processed fats (triglycerides) and sugar after meals. The goal was to see if these measurements could predict who would have a heart attack or die from hea…

This study tested a new AI system called X Life that gives personalized health advice to people with type 2 diabetes or prediabetes. The system uses data from continuous glucose monitors, activity trackers, and sleep sensors. Twenty participants used the system to see if it was e…

This study looked at 120 people having hand or wrist surgery to see if nerve blocks last longer in those with kidney failure or diabetes. Researchers measured how long numbness lasted after the block. The goal was to understand how metabolic diseases affect nerve block recovery.