University Of Florida

This study tested a probiotic called Lactobacillus johnsonii N6.2 in 30 children and teens with type 1 diabetes. The goal was to see if it is safe and if it can help preserve the body's ability to produce insulin by improving gut health. Participants took the probiotic for 24 wee…

This study tested whether a virtual coach, accessed through a patient portal, could help people with obesity lose weight before ventral hernia surgery. Researchers compared weight loss over six months between those using the coach and those receiving usual care. The goal was to s…

This study tested whether keeping donor lungs at 10°C (instead of the usual ice-cold temperature) allows lung transplants to be scheduled during daytime hours instead of overnight. Forty-five people receiving their first lung transplant took part. The main goal was to see if this…

This study tested an inhaled drug called treprostinil in 5 people with sarcoidosis who also had high blood pressure in the lungs and lung scarring. The goal was to see if the drug could improve blood flow and exercise ability. The treatment is meant to manage symptoms and slow di…

This study tested whether adding calcium to standard oral rehydration solution (ORS) helps adults with severe watery diarrhea, including cholera, recover faster. 396 adults aged 18-60 with acute diarrhea were randomly assigned to receive either calcium-enriched ORS or standard OR…

This study tested whether the weight-loss drug phentermine/topiramate could help control uric acid kidney stones in people with obesity and type 2 diabetes or pre-diabetes. 19 participants were randomly assigned to either the drug or standard care (citrate, allopurinol, diet) for…

This study tested whether community health workers can help adults with high blood pressure who also struggle to afford food. 75 participants received support to eat more fruits and vegetables and manage their blood pressure. The goal was to see if this approach is practical and …

This study tested whether minocycline, an inexpensive antibiotic, can lower blood pressure in people whose hypertension does not respond to standard medications. Researchers gave 34 adults with resistant hypertension low or high doses of minocycline to see if it reduced daytime b…

This study looked at whether giving steroids twice a week (instead of daily) and adding exercise training could help boys with Duchenne muscular dystrophy (DMD) keep their muscle strength longer. The goal was to find a way to reduce side effects from daily steroids while still sl…

This study tested a mobile health tool called AIM2ACT designed to help adolescents aged 12-15 with poorly controlled asthma and their caregivers better manage the condition. The goal was to see if using the app improves asthma control, measured by a standard questionnaire. The st…

This study tested two ways to help people maintain weight loss after an initial program. 255 adults with obesity who lost at least 5% of their body weight were randomly assigned to receive either monthly phone coaching or coaching only when a computer algorithm predicted they wer…

This study tested a computer-based decision support tool in primary care clinics. The tool was designed to help doctors and patients with chronic pain work together to choose treatment plans. The goal was to see if using this tool would lead to more shared decision-making and pot…

This study tested a mobile app called Family Fit designed to help parents and their children (ages 9-12) become more physically active and prevent weight gain. A total of 30 parent-child pairs used the app, and researchers measured how often they used it and how much they liked i…

This study tested whether giving warm, moist oxygen at a high flow rate through a tracheostomy tube can prevent lung complications (like pneumonia or collapsed lungs) after major head and neck surgery. 56 adults who had surgery with a tracheostomy were randomly assigned to receiv…

This study looked at whether a 12-week supervised aerobic exercise program can help mid-life adults with opioid use disorder feel less pain and move better. Only 6 people took part, so the main goal was to see if such a program is possible to run. The results will help design lar…

This study looked at whether 12 weeks of respiratory strength training could improve swallowing and breathing in people with Friedreich's ataxia. One participant completed the program, with tests before and after to measure lung function, swallowing, and muscle activity. The goal…

This pilot study tested whether taking krill oil supplements for 12 weeks could help older adults (age 60+) with long-term hip, knee, or lower back pain. The main goal was to see if people would stick with the supplement and find it acceptable. The study also measured changes in …

This study tested a smartphone-based prayer program called PUSH (Pray Until Something Happens) to see if it could help adults with sickle cell disease feel less stress and pain. 40 people who had pain and used opioids took part. They listened to guided prayer recordings on their …

This study tested whether drinking 100% orange juice every day for 12 weeks could improve skin health in women. Twenty women with fair skin participated. Researchers measured how the skin reacted to UV light, moisture loss, and redness to see if orange juice helped protect agains…

This study tested whether adding a special daily-activity program to usual home rehabilitation helps frail older adults improve tasks like bathing and dressing. 47 people aged 65+ with multiple health conditions took part. The program aimed to make everyday activities easier and …

This study tested a group breathwork program for adults with chronic musculoskeletal pain. Researchers wanted to see if the program was practical and liked by participants, and if it could help reduce pain intensity and interference. The study involved 35 people and focused on fe…

This study looked at whether a 4-week course of self-administered oxytocin nasal spray can reduce pain and improve daily function in older adults with knee osteoarthritis. Researchers compared the spray to a placebo in 83 participants to see if it works and to understand how it a…

This study looked at whether a discreet, hands-free wearable breast pump could help Black mothers of critically ill infants in the NICU pump more often and produce more milk. Forty Black mothers were randomly assigned to use either the wearable pump with a tracking app or a stand…

This study tested different breast pump suction patterns to see which helps mothers of critically ill infants produce more milk. 96 mothers participated. The goal was to find the most effective way to help these mothers provide enough milk for their babies.

This study tested a home-based digital exercise program for older adults who survived sepsis. 21 participants were assigned to either the exercise program or standard care. The goal was to see if remote exercise could safely improve physical function after hospital discharge.

This study tested whether personalized text message reminders could help mothers of critically ill infants in the NICU pump more breast milk. 122 mothers participated, receiving real-time biomarker-based texts to encourage pumping. The goal was to see if this approach increased m…

This study tested whether using nerve blocks with sedation instead of general anesthesia and opioids is safer and provides better pain control for high-risk patients needing an upper leg amputation. The study included 30 adults with conditions like diabetes, heart disease, or lun…

This study tested whether breathing low-oxygen air in short bursts (acute intermittent hypoxia) can boost the brain's ability to improve swallowing safety in people with chronic mild-to-moderate traumatic brain injury. Five adults completed the trial, which paired the breathing t…

This study tested a 4.5-hour somatic psychoeducational program for healthcare providers to see if it could improve their mental and physical health. 31 nurses participated, completing surveys and giving saliva samples before, one week after, and one month after the program. Resea…

This study tested whether the antidepressant fluoxetine could reduce depression, anxiety, and other mental health problems in people who had surgery for broken bones after a serious injury. About 68 adults took part. The goal was to see if a short course of medication, given by s…

This study tested a special breathing program called Guided Respiration Mindfulness Therapy for adults with chronic low back pain. Nineteen people took part in eight weekly one-hour breathing sessions. The goal was to see if the therapy was practical and liked by participants, an…

This study tested whether a guided relaxation program on a tablet could help adults with sickle cell disease better manage pain and stress while in the hospital. 46 participants used the program to listen to and view calming scenes. The goal was to see if this simple, drug-free a…

This study tested whether regular supportive phone calls could improve mental health in older adults who receive meal services and may feel lonely or isolated. Over 670 participants aged 55+ either received 8 weeks of 'warm calls' from trained helpers or were in a comparison grou…

This study looked at gut tissue from 35 people with and without high blood pressure who were already scheduled for a colonoscopy. Researchers grew mini-guts in the lab to compare gene activity and growth patterns. The goal was to understand if gut differences are linked to hypert…

This study tested how a very low-carbohydrate ketogenic diet compares to a Mediterranean diet for bone health and muscle function in older adults. Researchers enrolled 12 postmenopausal men and women to see if the diets affect bone metabolism and muscle decline. The goal was to g…

This study followed 378 people with moderate-to-severe Lewy body dementia and their caregivers for up to three years. Researchers used questionnaires and brief checkups to track symptoms, quality of life, and caregiver experiences as the disease progressed. The goal was to find c…

This study looked at brain signals in 21 people with essential tremor or Parkinson's disease during deep brain stimulation (DBS) surgery. Researchers placed temporary recording strips on the brain's surface to measure electrical activity. The goal was to better understand how tre…

This study tested whether using a special two-angle ultrasound (biplane) helps doctors give numbing medicine to children more accurately than the usual single-angle method. It involved 46 boys having circumcision surgery. The goal was to see if the biplane approach leads to fewer…

This small pilot study tested whether drinking beet juice could improve blood vessel and breathing muscle function in older adults with coronary artery disease. Eight participants completed the trial, which was designed mainly to see if a larger study is possible. Results are pre…

This study tested whether wearing Invisalign aligners for only 3 days (instead of the usual 7) could still move teeth predictably. Forty healthy adults with mild crowding participated. Researchers compared tooth movement accuracy and speed between the two wear schedules to see if…

This study looked at how limiting eating to certain hours of the day (time-restricted eating) affects energy use and daily body rhythms in overweight adults aged 65 and older. Researchers used wearable rings and blood tests to track changes in metabolism, sleep, and activity. The…

This study looked at 29 boys with autism aged 6 to 8 to understand how sensory interventions change the brain. Researchers used MRI scans and behavior tests before and after treatment. The goal was to find out which therapies work best for each child, helping them participate mor…

This study looked at whether a dietary fiber from baker's yeast (beta-glucan) can improve how well the flu vaccine works in healthy adults aged 50 and older. 78 participants took either the supplement or a placebo before getting their flu shot. Researchers measured antibody level…

This study tested a mixed-reality simulator that uses a virtual coach to teach a life-saving emergency procedure called REBOA. The goal was to see if the virtual coach could train people as well as a human instructor. Fourteen adults participated, and the study compared how quick…

This study tested a digital conversation aid to help patients and doctors make shared decisions about thyroid biopsy. Researchers enrolled 107 adults with thyroid nodules to see if using the tool during clinic visits was practical. The goal was to gather information for a future …

This study looked at whether the way a catheter is pushed off the needle during IV insertion changes how much the needle tip moves. 80 healthcare workers with IV experience tested three techniques: one-handed, two-handed, and two-person. The goal was to find which method causes t…

This study aimed to find a way to measure frataxin mRNA in blood and spinal fluid from people with Friedreich's ataxia. The researchers used tiny particles called exosomes to detect the mRNA. Ten adults with the disease provided samples during one visit. If successful, this metho…

This study looked at how sleep affects balance and thinking in healthy adults aged 65 and older. Over six weeks, 18 participants wore an OURA ring and kept a sleep diary while doing balance and memory tests. The goal was to understand daily connections between sleep, mobility, an…

This pilot study looked at how a single dose of methylphenidate (Ritalin) changes attention and cravings when people with both ADHD and alcohol use disorder see alcohol-related images. 31 young adults completed brain scans, EEG, and behavioral tests after taking either the drug o…

This study followed 53 ICU patients who had severe abdominal infections to understand why some become frail, weak, and disabled long after leaving the hospital. Researchers measured changes in muscle loss, mobility, and overall health over 12 months. The goal was to define the na…

This study tested a new service that lets parents in Ghana get medical help for their sick children at night by phone, with medicines delivered to their home. The goal was to see if this approach is safe and practical for treating common childhood illnesses like pneumonia and dia…

This study looked at 80 adults with rotated canine teeth to see which method works best with clear aligners: special attachments, a technique called IPR (slightly shaving tooth sides), or both. Researchers used 3D scans to measure how accurately the teeth moved. The goal is to he…