University Of Florida

This study tested whether a virtual coach delivered through a patient portal could help obese patients lose weight before ventral hernia surgery. Researchers compared the virtual coach approach to usual care for 32 patients over six months. The goal was to see if this digital too…

This study tested whether an inhaled medication called treprostinil could help people with sarcoidosis who have two related lung problems: scarring (interstitial lung disease) and high blood pressure in the lungs (pulmonary hypertension). The goal was to see if this targeted, inh…

This study tested a new method for storing donor lungs before a transplant. Researchers wanted to see if keeping lungs at a specific cold temperature (10°C) overnight allowed them to safely delay the transplant surgery until morning. They compared the outcomes of 45 patients who …

This study looked at whether a different way of taking a common steroid medicine (prednisone just twice a week instead of daily) could help boys with Duchenne muscular dystrophy (DMD) maintain muscle strength while causing fewer side effects like weight gain. It also tested if a …

This study tested different clear aligner techniques to see which works best for rotating canine teeth. Researchers compared three approaches: special attachments on teeth, tooth reshaping (IPR), and a combination of both. The trial involved 80 adults with rotated canine teeth wh…

This study tested whether trained community health workers could help adults with high blood pressure who struggle to afford healthy food. 75 participants from specific Florida zip codes were randomly assigned to receive either basic information, educational sessions, or educatio…

This study tested a computer-based decision support tool designed to help doctors and patients work together on chronic pain treatment plans. It involved 39 patients with chronic musculoskeletal pain and a history of opioid use from primary care clinics. The main goal was to see …

This study tested two ways to help people maintain weight loss using phone support. After participants lost at least 5% of their weight in a program, they received follow-up calls either monthly or only when an algorithm predicted they were at high risk for regaining weight. The …

This study tested whether minocycline, a common antibiotic, could help lower blood pressure in people whose high blood pressure was not controlled by three or more standard medications. Researchers gave 34 participants increasing doses of minocycline over six months to see if it …

This study tested whether adding calcium to standard oral rehydration solution (ORS) could reduce the severity and duration of acute watery diarrhea in adults. Researchers compared the new calcium-enhanced ORS against the standard WHO formula in 396 adults with diarrhea in Bangla…

This study tested whether a weight loss medication (phentermine/topiramate) could help control kidney stone formation in people who are obese and have diabetes or pre-diabetes. Over 18 months, researchers compared the medication against standard treatments in a small group of 19 …

This project tested a new nighttime service to help sick children in Ghana get care faster. Parents could call a hotline, and trained medical staff would assess the child by phone, visit their home if needed, and deliver medications. The goal was to treat common childhood illness…

This study tested whether a specific probiotic (Lactobacillus johnsonii N6.2) is safe and can help preserve the body's ability to make insulin in children and teenagers with type 1 diabetes. Researchers wanted to see if this probiotic could improve gut health and the immune syste…

This study tested whether changing the suction pattern on a breast pump could help mothers of babies in intensive care produce more milk. Researchers compared three different pump settings over seven days for 96 mothers who were struggling to make enough milk after their milk had…

This study tested if sending personalized text messages could help mothers of critically ill newborns in intensive care pump breast milk more often and produce more of it. Researchers sent some moms text messages with their personal breast milk sodium level (a sign of pumping fre…

This study tested whether a breathing treatment called acute intermittent hypoxia (AIH) could help improve swallowing safety in people with chronic traumatic brain injury. Participants were adults with mild-to-moderate brain injuries who received either the breathing treatment pl…

This study tested an electronic conversation aid designed to help patients and their doctors work together to decide if a thyroid nodule needs a biopsy. It involved 107 adults with thyroid nodules to see if using the tool was practical and acceptable. The main goal was to see if …

This study tested whether taking a daily supplement called beta-glucan, a fiber from baker's yeast, could improve the body's immune response to the seasonal flu vaccine. It involved 78 healthy adults aged 50 and older. Participants took either the supplement or a placebo pill for…

This study tested if a special heated and humidified oxygen therapy could better prevent lung complications in patients recovering from major head and neck surgery, compared to standard oxygen therapy. It involved 56 patients who had surgery requiring a temporary breathing tube (…

This study tested whether a mobile app could help families become more active and prevent weight gain. Researchers worked with 30 parent-child pairs who weren't getting enough exercise to try the app for 12 weeks. The main goal was to see if families found the app easy to use and…

This study tested whether a discreet, hands-free, wearable breast pump could help Black mothers of critically ill newborns produce more breast milk. Researchers compared the wearable pump with a tracking app against a standard mechanical pump in 40 mothers. The goal was to see if…

This study tested whether adding a special program focused on daily tasks (like dressing and moving around) to standard home health therapy could help frail older adults regain their independence. Researchers compared two groups of patients over 65: one received the new program p…

This study tested whether using targeted nerve blocks with sedation is a safer and more effective way to control pain during leg amputation surgery compared to general anesthesia. It focused on high-risk patients with conditions like diabetes, heart disease, and lung disease. The…

This small pilot study tested whether taking krill oil supplements could help older adults with long-term joint or back pain. Researchers enrolled 40 participants aged 60 and over to see if the supplement was practical to study and might improve pain levels and physical function.…

This study tested a short educational program designed to help healthcare workers, specifically nurses, manage work-related stress. Thirty-one nurses participated in a 4.5-hour program over three weeks, which included lessons on breathing, movement, and stress management. Researc…

This study tested whether a 12-week program of breathing exercises could help people with Friedreich's ataxia swallow more safely and breathe better. Researchers measured lung strength and swallowing ability before and after the training in one participant. The goal was to see if…

This study tested whether an 8-week program of supportive phone calls could improve mental health for older adults at risk of loneliness and depression. Researchers enrolled 671 adults aged 55+ who were receiving meal services from senior centers. Participants received weekly 'wa…

This study tested whether a simple, non-drug approach could help adults with sickle cell disease manage pain and stress while in the hospital. Researchers had 46 patients try a tablet program with guided relaxation videos to see if it was practical and helpful. The goal was to se…

This small study explored whether a supervised 12-week exercise program could help adults being treated for opioid use disorder. It aimed to see if regular aerobic exercise could reduce their pain and improve their ability to move. The main goal was to test if this type of progra…

This study tested whether a nasal spray containing oxytocin, a natural hormone, could safely reduce pain and improve daily function in older adults with knee osteoarthritis. Over 80 participants used the spray or a placebo daily for four weeks. Researchers measured changes in pai…

This small pilot study tested whether drinking orange juice daily could improve skin health and reduce signs of aging. Twenty women drank either orange juice or a look-alike placebo drink for 12 weeks. Researchers measured changes in skin redness from sun exposure, hydration, ela…

This study aimed to better understand what happens as people with Lewy body dementia approach the end of life. Researchers followed 378 patient-caregiver pairs for three years through questionnaires and check-ins every six months. The goal was to identify signs that could predict…

This study tested whether a computer-based virtual coach could train medical staff as effectively as a human instructor for a critical emergency procedure called REBOA, which is used to stop life-threatening bleeding. Fourteen healthcare trainees practiced the procedure on a mixe…

This study aimed to find a new way to measure a specific biological signal (frataxin mRNA) in the blood and spinal fluid of people with Friedreich's ataxia. Researchers tested 10 adult patients to see if this measurement could serve as a useful tool to track the disease and monit…

This study aimed to understand how essential tremor happens in the brain and how deep brain stimulation (DBS) therapy helps control it. Researchers recorded brain signals from 21 people with essential tremor or Parkinson's disease while they were having DBS surgery. By listening …

This small pilot study aimed to gather initial information on how two different diets affect bone health and muscle function in older adults. Researchers compared a very low-carb ketogenic diet to a Mediterranean diet over six weeks in 12 participants. The goal was to collect ear…

This small, early-stage study aimed to understand if a single dose of methylphenidate (Ritalin) could change how people with both alcohol use disorder and ADHD react to alcohol-related images and cravings. Researchers gave 31 young adults either the medication or a placebo and us…

This study aimed to find the safest way to slide the plastic tube (catheter) off the needle during an IV start. Researchers watched how much the needle tip moved when nurses used one hand, two hands, or had a helper do it. The goal was to identify which technique causes the least…

This study aimed to understand if there are differences in the gut lining of people with high blood pressure compared to those without it. Researchers analyzed small tissue samples taken during routine colonoscopies from 35 adults. They looked at gene activity and grew mini-gut m…

This study aimed to understand how sensory-based activities might change brain structure in children with autism. Researchers used MRI scans and behavioral tests on 29 boys aged 6-8 years to see if they could predict which sensory interventions might work best for different child…

This study aimed to understand how sleep quality is connected to balance and mental sharpness in healthy adults over 65. For six weeks, 18 participants wore a sleep-tracking ring and visited a lab weekly for balance and memory tests. The goal was to gather information to help dev…