New biomarker could help monitor treatments for rare nerve disease

NCT ID NCT06496451

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 25 times

Summary

This study aimed to find a way to measure frataxin mRNA in blood and spinal fluid from people with Friedreich's ataxia. The researchers used tiny particles called exosomes to detect the mRNA. Ten adults with the disease provided samples during one visit. If successful, this method could help doctors monitor whether treatments are working to increase frataxin levels in the brain.

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Contacts and locations

Locations

  • University of Florida

    Gainesville, Florida, 32608, United States

Conditions

Explore the condition pages connected to this study.