New study aims to predict end of life in lewy body dementia

NCT ID NCT04829656

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study followed 378 people with moderate-to-severe Lewy body dementia and their caregivers for up to three years. Researchers collected surveys and some physical exams to track symptoms, caregiver stress, and quality of life. The goal was to find clues that signal when a person is in their last six months of life, so families and doctors can better prepare and provide comfort.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help doctors and families better predict when someone with Lewy body dementia is nearing the end of life, leading to more compassionate and timely care.

What could go wrong

This is an observational study, not a treatment trial, so it won't directly change the course of the disease. The findings may not apply to everyone with DLB, especially those outside the U.S.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

dementia Lewy body dementia Lewy Body Disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • University of Florida

    Gainesville, Florida, 32608, United States

  • University of Miami

    Miami, Florida, 33136, United States

  • University of Michigan

    Ann Arbor, Michigan, 48105, United States

  • University of Virginia

    Charlottesville, Virginia, 22903, United States