New study aims to predict end of life in lewy body dementia

NCT ID NCT04829656

Completed Knowledge-focused Sponsor: University of Florida Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study followed 378 people with moderate-to-severe Lewy body dementia and their caregivers for up to three years. Researchers collected surveys and some physical exams to track symptoms, caregiver stress, and quality of life. The goal was to find clues that signal when a person is in their last six months of life, so families and doctors can better prepare and provide comfort.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors and families better predict when someone with Lewy body dementia is nearing the end of life, leading to more compassionate and timely care.
What could go wrong: This is an observational study, not a treatment trial, so it won't directly change the course of the disease. The findings may not apply to everyone with DLB, especially those outside the U.S.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

dementia Lewy body dementia Lewy Body Disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEMENTIA WITH LEWY BODIES

Contacts and locations

Locations

Mayo Clinic

Rochester, Minnesota, 55905, United States
University of Florida

Gainesville, Florida, 32608, United States
University of Miami

Miami, Florida, 33136, United States
University of Michigan

Ann Arbor, Michigan, 48105, United States
University of Virginia

Charlottesville, Virginia, 22903, United States

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