Brain scans track Alzheimer's clues over decades
NCT ID NCT00950430
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study uses special brain scans (PET imaging) to measure amyloid buildup—a protein linked to Alzheimer's—in healthy older adults, people with mild memory problems, and those with dementia. Participants receive scans every 2-3 years for up to 20 years to see how amyloid changes over time and relates to memory decline. The goal is to improve early diagnosis and understanding of Alzheimer's and related dementias.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Pittsburgh Compound B (C-11 PiB) and F-18 FDG
What this could lead to
If successful, this could lead to better early detection and tracking of Alzheimer's and other dementias, helping doctors diagnose and monitor these diseases more accurately.
What could go wrong
This is an observational imaging study, not a treatment trial. It may not directly improve patient outcomes, and results may take many years to yield practical benefits.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Mayo Clinic
Rochester, Minnesota, 55905, United States