University Of Florida

This pilot study is testing whether a computer system using artificial intelligence (AI) can help doctors find the best doses of anti-rejection drugs for people who have received a kidney transplant. The goal is to protect the new kidney from damage while using the lowest effecti…

This study aims to find the best dose of a blood-thinning drug (cangrelor) for heart patients waiting for surgery. It will test if adjusting the dose based on a simple blood test keeps patients in a safer range compared to a standard fixed dose. The goal is to better control blee…

This study is testing whether a non-invasive light and sound therapy can help older adults who are worried about their memory but do not yet have a diagnosis of dementia. For three months, participants will use a device that delivers flickering sensory stimulation at home. Resear…

This study is testing a new 'adaptive' brain stimulation device for adults with spinocerebellar ataxia type 6 (SCA6), a rare genetic disorder that causes worsening problems with balance and coordination. Five participants will have a device surgically implanted in their brain to …

This early-stage study is testing a personalized RNA vaccine approach for children and young adults with recurrent medulloblastoma, a type of brain tumor. Researchers will create vaccines from each patient's own tumor RNA to train their immune system to fight the cancer. The main…

This study is testing whether giving patients high levels of oxygen soon after a severe spinal cord injury is safe and practical. It will involve 12 adults who are on a ventilator within 24 hours of their injury. The main goal is to see if this oxygen treatment can be delivered a…

This study is testing whether a single dose of the medication methylphenidate (Ritalin) can help young adults who misuse alcohol by reducing their cravings and brain reactions to alcohol-related pictures. Researchers will give participants either the medication or a placebo and u…

This study aims to test a new computer tool designed to help emergency room doctors identify patients at high risk for Hepatitis C and HIV. The tool uses a smart algorithm to analyze patient records and pop up an alert for doctors, suggesting they offer a screening test. Research…

This study is testing whether short, educational videos can help new mothers prevent their babies from developing obesity. Fifty mothers in a Florida home-visit program will watch videos about healthy feeding, sleep, and activity over one year. Researchers will compare the babies…

This study is testing a new behavioral support program designed for men who use stimulants and are at high risk for HIV. The goal is to see if the program helps participants reduce their drug use and start taking PrEP, a daily pill that prevents HIV infection. Researchers will en…

This study is testing if a single session of rehabilitation before using a breathing machine (ventilator) can prevent muscle weakness that makes it hard to breathe independently later. Researchers will compare two methods—breathing muscle training and gentle electrical spine stim…

This study is testing a new support program called PINPOINT to help women with diabetes or obesity get screened for cervical cancer. It will work with 20 women who are overdue for screening to see if the program is practical and well-liked. Participants will either receive the ne…

This study is testing whether a non-invasive ear stimulation device can help people feel less anxious during stressful performance situations. Researchers will randomly assign 200 healthy adults to use either an active or inactive version of the device while preparing a speech or…

This study is testing whether breathing muscle training can prevent weakness and breathing problems in adults newly diagnosed with breast cancer who are planning surgery. Researchers will compare breathing exercises to guided imagery relaxation techniques to see which helps more.…

This small, early-stage study is checking if a specially prepared, safer version of the traditional kava plant supplement can help improve walking ability, strength, and sleep quality in adults over 70 who have trouble sleeping and are not very active. Researchers will give 40 pa…

This study is testing whether three new patterns of deep brain stimulation (DBS) are safe and comfortable for people with Parkinson's disease to use at home. The study involves 60 people who already have a stable DBS implant. Each participant will try one of the new stimulation p…

This study is testing if a shorter, 5-week virtual brain training program is just as good as the standard 8-week program for older adults with mild cognitive impairment (MCI). Researchers want to see if the shorter version can still help improve memory, thinking, daily life, and …

This study aims to see if combining two treatments—a special light therapy called photobiomodulation and a topical pain-relief gel (diclofenac)—works better than light therapy alone for reducing inflammation, pain, and improving function in people with knee osteoarthritis. Resear…

This study is testing whether combining a non-invasive brain stimulation technique with virtual reality balance and walking exercises can improve mobility in people with mild cognitive impairment. It will involve 30 adults, half with and half without cognitive issues, who will co…

This study aims to understand how a focused ultrasound treatment changes brain activity in people with essential tremor, a condition causing shaky hands. Researchers will use special brain scans and movement tests on 10 participants before and after treatment to see how brain net…

This study aims to better understand the gum problems and success rates of a common dental device used in children. Researchers will follow 50 children, aged 3-9, who need a 'distal shoe' space maintainer after losing a baby molar too early. The goal is to identify what causes co…