Engineered immune cells take on childhood brain cancer in first human trial

NCT ID NCT06946680

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This early-phase study tests a new treatment for children and young adults with aggressive brain tumors called high-grade glioma and DIPG. The therapy uses the patient's own immune cells, modified in a lab to better recognize and attack tumor cells. The main goals are to see if the treatment is safe and possible to deliver. About 24 participants will be enrolled.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

brain cancer diffuse intrinsic pontine glioma glioblastoma glioma malignant glioma pediatric high-grade glioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Florida Health Children's Hospital

    Gainesville, Florida, 32608, United States