Baylor College Of Medicine

This early-phase study is testing the safety of a new treatment for people with recurrent or treatment-resistant brain tumors that have a specific marker called HER2. Doctors take a patient's own immune cells (T cells), modify them in a lab to better recognize and attack the canc…

This study is testing a new treatment for cancers linked to the human papillomavirus (HPV) that have returned or not responded to standard therapies. Researchers take a patient's own immune cells, grow them in a lab, and engineer them to better recognize and attack HPV-infected c…

This early-phase study is testing a new type of cell therapy called AGAR T cells in children and young adults with solid tumors that have come back or haven't responded to standard treatments. Doctors take a patient's own immune cells, modify them in a lab to better recognize and…

This early study tested whether adding a drug called AZA to standard steroid treatment could better control a serious complication called graft-versus-host disease (GVHD) that affects the gut after a transplant. The goal was to see if this combination was safe and could protect t…

This study is testing whether a protein supplement called carnitine can reduce artery stiffness in teenagers who are at risk for future heart problems. Researchers will give carnitine or a placebo to 90 teens with high triglycerides for six months to see if it improves artery hea…

This study is comparing two ways to perform a delicate surgery on unborn babies with spina bifida, a serious spinal cord defect. Doctors are testing if using a collagen patch during a minimally invasive 'fetoscopic' repair leads to a stronger, thicker closure of the defect compar…

This early-stage study is testing a new combination treatment for children and young adults with advanced osteosarcoma or neuroblastoma that has come back or hasn't responded to standard therapies. Doctors take a patient's own immune cells, genetically modify them to better recog…

This study is testing whether Invisalign clear aligners are a safe and effective way to straighten teeth for people with Osteogenesis Imperfecta (OI), also known as brittle bone disease. Traditional braces are often too risky for people with OI because their tooth enamel is fragi…

This is an early-stage safety study testing a new type of cell therapy for adults with certain recurring B-cell blood cancers (like lymphoma, myeloma, or CLL) that have not responded to standard treatments. Doctors take a patient's own immune cells (T cells), genetically modify t…

This early-stage study is testing a new type of cell therapy for acute myeloid leukemia (AML) that has returned or not responded to standard treatments. Doctors take a patient's own immune cells (T cells), modify them in a lab to better recognize and attack the leukemia cells, an…

This early-phase study tests a new cell therapy for patients whose Hodgkin's or Non-Hodgkin's lymphoma has returned. Doctors take a patient's own immune cells, genetically modify them in a lab to better recognize and attack cancer cells, and then infuse them back. The main goal i…

This is an early-stage safety study testing a new type of treatment for patients whose B-cell lymphoma or leukemia has returned or not responded to standard therapies. Doctors take a patient's own immune cells (T cells), genetically modify them in a lab to better recognize and at…

This study is testing a modified bone marrow transplant procedure for adults and children with serious blood cancers and disorders. The goal is to treat the underlying disease while reducing the risk of a dangerous complication called graft-versus-host disease. Researchers use a …

This study tests a new treatment for cancers linked to the Epstein-Barr virus (EBV) that have come back or haven't responded to standard care. Doctors are using a bank of pre-made immune cells from healthy donors, which are specially trained to attack EBV-infected cancer cells, a…

This study is testing a new cell therapy for lymphoma that has come back after treatment and is linked to Epstein-Barr virus (EBV). Researchers are giving patients special immune cells (T cells) that have been genetically modified to resist a substance released by the tumor and t…

This early-stage study is testing a new therapy for people with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) that has returned or persists after standard treatment, including a stem cell transplant. Researchers take immune cells (T cells) from the patient's orig…

This early-stage study is testing a new type of treatment called CATCH T cells in adults with advanced solid tumors that have a specific marker (GPC3). Doctors take a patient's own immune cells, genetically modify them in a lab to better recognize and attack cancer, and then infu…

This early-stage study is testing a new treatment called GAP T cells in children and young adults with liver cancer that has come back or hasn't responded to standard treatments. Doctors take a patient's own immune cells, genetically modify them in a lab to recognize and attack c…

This study is looking at whether a simple oral care treatment can help babies born with gastroschisis, a condition where the intestines are outside the body. Researchers are observing 27 infants to see if gently applying the mother's breast milk (or sterile water if milk isn't av…

This study is testing a new treatment for advanced sarcoma, a type of cancer. Doctors take a patient's own immune cells (T-cells), genetically modify them in a lab to recognize and attack cancer cells, and then infuse them back into the patient. The main goals are to find the saf…

This early-phase study is testing the safety of a new cell therapy for patients whose blood cancer (like leukemia or lymphoma) has come back after a stem cell transplant from a donor. Doctors take immune cells (T cells) from the donor, genetically modify them in a lab to better r…

This early-stage study is testing a new type of cell therapy for patients with EBV-positive nasopharyngeal cancer that has returned or not responded to standard treatments. Doctors take a patient's own immune cells, modify them in a lab to better recognize and attack cancer cells…

This study is testing if a non-invasive headband device, already approved for migraines, can help reduce seizures in veterans with epilepsy that doesn't respond well to medication. 24 veterans will try using the device along with their usual care to see if it lowers how often the…

This study is testing a new, advanced ultrasound otoscope device to see if it can accurately diagnose middle ear infections in children. Researchers are collecting images and data from 300 children who are already scheduled for ear tube surgery. They will compare the device's rea…

This study is testing if mailing a simple, at-home HPV test kit can help more Asian and Asian American women get screened for cervical cancer. It focuses on women in a safety-net healthcare system who are overdue for their regular screening. The goal is to see if this convenient,…

This study is testing whether chewing xylitol gum during pregnancy can improve oral and vaginal bacteria, reduce gum inflammation, and potentially benefit infant development. Researchers in Malawi are enrolling 80 pregnant women who will chew either xylitol or placebo gum daily f…

This study is testing whether a brief home visitation program can help pregnant women and new mothers. It aims to help them connect to community resources, feel more confident about their health, and reduce stress. The program is delivered by trained non-nurse visitors and is bei…

This study is testing two different online therapy programs designed to help parents support their children with anxiety or obsessive-compulsive disorder (OCD). It involves 100 children aged 7-13 in Texas and compares these parent-led, therapist-supported online programs to a sim…

This study aimed to see if adding ear acupuncture during surgery could help patients use fewer opioid painkillers after having an ankle fracture repaired. It planned to compare patients who received the acupuncture along with standard pain control to those who received standard c…

This study aimed to see if adding ear acupuncture during wrist fracture surgery could help patients use fewer opioid painkillers afterward. It planned to compare two groups of adults getting the same surgery and standard pain plan, with only one group receiving the acupuncture. T…

This study aimed to see if a pill containing synthetic THC, the main active part of cannabis, could safely help reduce chronic pelvic pain in women with endometriosis. It was a small, early-stage trial where some participants would have received the THC pill and others a placebo …

This study aims to better understand dental and jaw alignment problems in people with moderate to severe Osteogenesis Imperfecta (brittle bone disease). Researchers will use 3D scans and X-rays to measure teeth misalignment and neck defects in 75 participants over time. The goal …

This study aims to see if a new urine test can help doctors better understand and classify different types of Osteogenesis Imperfecta (OI), a rare condition that makes bones break easily. Researchers will collect urine samples from 25 people with OI who have specific genetic muta…

This study aims to learn if certain markers in blood or saliva can help identify men who are at higher risk for developing HPV-related cancers, particularly in the throat. Researchers are enrolling 1,500 men to collect samples and track them over time to understand the link betwe…

This study aims to understand how premature babies grow and develop after they go home from the hospital, specifically those who were fed an exclusive human milk diet. Researchers will follow 51 very small premature infants who received donor human milk in the NICU, checking thei…

This study aims to understand why people with osteogenesis imperfecta (brittle bone disease) often develop serious breathing problems. Researchers will examine 18 adults with the condition through medical history, questionnaires, physical exams, and lung imaging tests. The goal i…

This study is checking on children who were very premature babies to see if the amount of protein they received in their hospital milk diet affects their growth, body composition, and brain development by age 2. It follows up on 120 infants who were part of an earlier hospital st…