Baylor College Of Medicine

This study tested different versions of an experimental hookworm vaccine in healthy adults who had never had hookworm. Participants received three vaccine shots or a placebo, and were later exposed to a small, controlled dose of hookworm larvae to see if the vaccine prevented inf…

This study tested a new vaccine designed to prevent schistosomiasis, a serious disease caused by parasitic worms. Researchers gave the vaccine to 290 healthy adults in Uganda to check if it was safe and if it could protect them from getting infected. They tested different doses a…

This study tested whether adding a prescription sleep medication (lemborexant) to a standard alcohol treatment drug (naltrexone) could help people with alcohol use disorder. The goal was to see if the combination reduced alcohol cravings and improved sleep quality better than the…

This early study tested whether a drug called atovaquone could be safely given alongside standard chemotherapy to children and young adults newly diagnosed with acute myeloid leukemia (AML). Researchers wanted to see if patients could tolerate the combined treatment and to measur…

This study tested whether giving very small premature babies (under 1000g) a high-protein human milk diet would help them grow better and develop healthier body composition compared to a standard protein diet. Researchers randomly assigned 118 infants to receive either the high-p…

This early-phase study tested the safety of a modified chemotherapy regimen, called dose-adjusted EPOCH-R, in children with aggressive B-cell cancers like diffuse large B-cell lymphoma. The treatment involved giving some drugs as a continuous infusion over four days and adjusting…

This early-phase study tested a new gene therapy approach for patients whose non-Hodgkin lymphoma or chronic lymphocytic leukemia had returned or didn't respond to standard treatments. Researchers modified patients' own immune T-cells in the lab to better recognize and attack the…

This study tested whether adding extra vitamin D to special formula for preterm babies helps them maintain healthy vitamin D levels and supports bone development. Researchers compared two different vitamin D amounts in 39 premature infants born between 28-34 weeks. They measured …

This study tested an experimental therapy using a patient's own immune cells, specially grown in a lab to recognize and attack pancreatic cancer. It involved 37 adults whose cancer had returned, was not responding to standard treatments, or who were scheduled for surgery. The mai…

This study tested a peer support program for young adults (ages 17-25) with type 1 diabetes as they move from pediatric to adult healthcare. Trained mentors, who also have type 1 diabetes, provided guidance and shared their own experiences over 12 months. The main goal was to see…

This study tested a new treatment for children with high-risk neuroblastoma, a serious childhood cancer. Researchers modified patients' own immune cells to better recognize and attack cancer cells, hoping these 'supercharged' cells would last longer in the body than previous vers…

This study tested if adding a concentrated cream made from human milk to regular breast milk helps very small premature babies gain weight better. It involved 78 infants born weighing between 1.6 and 2.8 pounds. Babies were randomly assigned to receive either milk with the extra …

This study tested a new counseling program called THRIVE for people with HIV who were hospitalized and had not been regularly seeing their HIV doctor. The program aimed to help 75 participants overcome feelings of avoidance and stigma so they would continue their outpatient HIV c…

This study tested whether adding a calorie-boosting cream made from human milk to the diet of very premature babies could help them leave the hospital earlier. Researchers compared 210 tiny babies who received the cream supplement to those who did not. They also checked if the cr…

This study tested if mailing HPV self-test kits to women's homes could help more underserved women get screened for cervical cancer. Researchers compared three different outreach methods, including phone calls and mailed kits, to see which worked best. The goal was to find a prac…

This study tested if a simple program could help prevent type 2 diabetes in Hispanic teenagers with obesity. Researchers gave 43 teens a Fitbit and sent them encouraging text messages for 12 weeks to help them move more and sleep better. The main goal was to see if this tech-base…

This study tested whether a special therapy program for anxiety could work well in local community centers for autistic children and teens. Researchers adapted a proven talk therapy to be more accessible and studied if families and clinics could use it. The goal was to see if thi…

This study tested whether adding acupuncture during gallbladder removal surgery helps prevent nausea and vomiting afterward. Researchers compared patients who received standard anti-nausea medications alone versus those who also received acupuncture at specific points during thei…

This small pilot study tested whether a mobile app with guided relaxation sessions could help children with chronic stomach pain. Kids aged 7-12 with functional abdominal pain disorders used the app for 8 weeks, listening to 10-15 minute sessions most days. Researchers measured c…

This study aimed to find out if simple body measurements could predict which of two common treatments would work better for children with chronic stomach pain. Researchers tested 163 children aged 7-12 to see if their heart rate, gut bacteria, or other body signals could show whe…

This study observed very small premature babies receiving donor human milk in the hospital to understand if current feeding practices are safe. Researchers tracked 150 infants weighing 1250 grams or less to check for electrolyte imbalances that can cause serious health problems. …

This study observed children who stayed overnight in the hospital after having surgery to treat sleep apnea. Researchers monitored their oxygen levels to better understand which patients actually need this overnight monitoring and which could safely go home sooner. The goal is to…