Baylor College Of Medicine

This study tested a new vaccine (Sm-TSP-2) to protect against intestinal schistosomiasis, a parasitic disease common in parts of Africa. Healthy adults in Uganda received different doses of the vaccine, with or without an immune booster, to check safety and whether it reduces inf…

This study tested a new vaccine to prevent hookworm infection in 39 healthy adults who had never had hookworms. Participants received different versions of the vaccine and were then exposed to hookworms in a controlled setting to see if the vaccine could protect them. The main go…

This study tested whether trained peer mentors (ages 20-35) could help young adults (ages 17-25) with type 1 diabetes better control their blood sugar and smoothly transition from pediatric to adult diabetes care. The 144 participants were randomly assigned to receive the peer me…

This study tested a new treatment for people with HPV-related cancers that came back or didn't respond to standard care. Researchers took immune cells (T cells) from patients' blood, trained them to attack HPV-infected cancer cells, and gave them back. The goal was to find a safe…

This study looked at whether adding human milk cream to breast milk or donor milk could help very low birth weight preterm infants (weighing 750-1250 grams) get enough calories to grow better. Researchers measured the calorie content of the milk and tracked the babies' weight, le…

This study looked at whether adding a cream supplement made from human milk to the diet of extremely premature infants (weighing 500-1250 grams) could shorten their hospital stay. 210 babies were randomly assigned to receive either standard human milk or human milk with extra cre…

This study tested a new way of giving chemotherapy called dose-adjusted EPOCH-R in children with certain B-cell cancers (DLBCL, PMBCL, or PTLD). The goal was to see if it is safe and could improve cure rates while reducing side effects, as it has in adults. Only 4 children took p…

This study tested a new treatment for children with high-risk neuroblastoma, a type of cancer. Researchers took the children's own immune cells (T cells) and modified them to better recognize and attack cancer cells. Some of these cells were also trained to fight a common virus t…

This early-phase study tested a new approach for people with advanced B-cell non-Hodgkin lymphoma or chronic lymphocytic leukemia (CLL) that had returned or not responded to standard treatments. Researchers took patients' own immune cells (T cells) and added a special receptor (a…

This study tested a new experimental therapy using special immune cells (T cells) trained to attack five proteins found on pancreatic cancer cells. It included 37 patients whose cancer had returned, not gone away, or who could not have standard chemo. The main goals were to see i…

This study tested a program called THRIVE for 75 hospitalized adults with HIV who were not regularly seeing a doctor. The program provided support to help them attend follow-up appointments after leaving the hospital. The goal was to improve viral load control and reduce anxiety …

This study tested whether adding a prescription sleep medication (lemborexant) to a standard alcohol use disorder drug (naltrexone) could help reduce alcohol cravings and improve sleep. It involved 8 adults with both alcohol use disorder and insomnia. Researchers compared the com…

This study tested whether adding acupuncture to standard anti-nausea medication can better prevent nausea and vomiting after gallbladder removal surgery. 270 adults scheduled for laparoscopic cholecystectomy received either acupuncture at specific points plus standard drugs, or s…

This study tested whether mailing HPV self-test kits to women who rarely or never get screened for cervical cancer could increase participation. Over 2,400 underserved minority women in Texas received either a mailed kit or usual care. The goal was to see if at-home testing makes…

This study tested a special anxiety program designed for autistic children and teens ages 7 to 17. The program was offered in community care centers to make it easier to access. Researchers wanted to see if the program was practical and helpful for reducing anxiety symptoms. The …

This study tested if a mobile app with guided imagery therapy could help children aged 7 to 12 with chronic belly pain. Four children used the app for 8 weeks, listening to 10-15 minute sessions five days a week. The goal was to see if the app could reduce pain and anxiety. The s…

This study looked at a newer biopsy method called fine needle biopsy (FNB) for diagnosing pancreatic masses. Researchers wanted to see if FNB could provide better tissue samples than the standard method, fine needle aspiration (FNA), without needing a cytologist on site. The stud…

This study looked at whether giving very small premature babies (under 1000 grams at birth) a diet with extra protein helps them grow better and build more muscle. The babies received only human milk with added protein based on individual needs. The goal was to see if this approa…

This early-phase trial tested adding atovaquone (a drug usually used to prevent pneumonia) to standard chemotherapy for children, teens, and young adults with newly diagnosed acute myeloid leukemia (AML). The main goals were to see how often doses had to be skipped due to side ef…

This study looked at how very low birth weight babies (under 1250 grams) are fed donor human milk in the NICU. The goal was to see if current feeding practices follow guidelines and to check for electrolyte imbalances that can cause serious symptoms. The study involved 150 premat…

This study looked at 178 children who had their tonsils removed to treat sleep apnea. After surgery, they wore a special monitor to track oxygen levels. The goal was to find out how often oxygen drops happen after children go home from the hospital.

This study looked at whether adding extra vitamin D to the formula of preterm infants (born 28-34 weeks) helps them reach healthy vitamin D levels and improves bone health. 39 babies participated, receiving either standard or extra vitamin D in their formula. The main goal was to…

This study tested a program that used a Fitbit activity tracker and text messages to help Hispanic teenagers with obesity become more active and improve their sleep. The study included 43 teens aged 14-16 who owned a cellphone. The main goal was to see if the program was practica…

This study looked at 163 children aged 7-12 with chronic belly pain (like irritable bowel syndrome) to see if simple tests could predict whether they would benefit more from cognitive behavioral therapy (CBT) or a low FODMAP diet. The goal was to personalize treatment and avoid t…