Baylor College Of Medicine

This early-stage trial tests whether adding vitamin C to standard steroid treatment can help people with gastrointestinal graft-versus-host disease (GVHD), a serious complication after a donor stem cell transplant. GVHD occurs when donor cells attack the patient's body, especiall…

This early-phase study tests a new treatment for people with certain blood cancers (like acute myeloid leukemia) that have come back or not responded to standard care. Researchers take a patient's own immune cells, modify them in the lab to recognize and attack cancer cells carry…

This early-phase trial tests a new type of cell therapy called HTR2 T cells in people with metastatic breast cancer that has HER2 protein on its surface and has not responded to standard treatment. The therapy uses a patient's own immune cells, modified to better recognize and at…

This early-phase study tests a new type of cell therapy for people with certain cancers (lymphoma, myeloma, and solid tumors like kidney cancer and sarcoma) that have returned or not responded to standard treatments. The therapy uses the patient's own T cells, which are modified …

This early-phase trial tests a new treatment for people with T-cell leukemia or lymphoma that has come back. The therapy uses donor T cells that are engineered in a lab to recognize and attack cancer cells carrying a protein called CD7. The study aims to find a safe dose and see …

This early-phase trial tests a new treatment for children with a rare and aggressive brain tumor called atypical teratoid rhabdoid tumor (ATRT) that has come back or not responded to standard therapy. The treatment uses the patient's own immune cells, modified in the lab to bette…

This study tests whether injections of platelet-rich plasma (PRP), made from a patient's own blood, can stop hair loss and promote regrowth in women with central centrifugal cicatricial alopecia (CCCA), a scarring hair loss condition common in women of African descent. About 56 w…

This early-phase study tests a new combination of two types of immune cells—NK cells and CAR-T cells—for people whose neuroblastoma or osteosarcoma has returned or not responded to standard treatments. The cells are modified to better recognize and fight cancer and to survive lon…

This study compares two approved cyclosporine eye drops (Vevye® and a generic) to see which one better increases mucus-producing cells in the eyes of people with dry eye disease. Sixty adults will use the drops daily for 8 weeks and have eye exams every 2 weeks. The goal is to fi…

This study tests whether a mobile app with guided imagery therapy can reduce chronic abdominal pain in children aged 7 to 12. Participants listen to 10-15 minute sessions five days a week for eight weeks, alongside their usual care. The goal is to see if this approach lowers pain…

This study tests a web-based support program (Hospital GamePlan4Care) for caregivers of veterans with dementia who are moving from a skilled nursing facility back home. About 55 caregivers will receive either tailored online training and phone coaching or standard education mater…

This study will test whether a disposable endoscope works well for certain stomach and esophagus procedures (e-POEM and g-POEM) in 40 adults with achalasia or gastroparesis. The goal is to see if the single-use scope is effective, safe, and easy for doctors to use. All participan…

This study aims to understand the brain and behavior patterns in people with severe obsessive-compulsive disorder (OCD) or bipolar disorder who are already scheduled for deep brain stimulation (DBS) surgery. Researchers will use wearable devices like smartwatches and rings to tra…

This study checks if a quick, painless skin scan can accurately measure how many fruits and vegetables toddlers eat. Researchers will compare the skin scan results with blood tests and food diaries from 150 healthy 2-year-olds. If the skin scan works well, it could give doctors a…